Download VNSGU MBBS 2nd Year 2019 Dec Pharmacology Paper I Question Paper

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RAN-3714

SECOND YEAR M.B.B.S. Examination

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December / January - 2019 / 2020

PHARMACOLOGY PAPER I

Time: 2 Hours ] [ Total Marks: 40

? : / Instructions

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Fill up strictly the details of signs on your answer book

Name of the Examination:

SECOND YEAR M.B.B.S.

Name of the Subject:

PHARMACOLOGY PAPER I

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Subject Code No.: 3 7 1 4 Seat No.: Student's Signature

Section -I

Q.I. Answer very briefly : 10

1. Explain synergistic action of drugs giving one example.
2. What is a placebo? Where are placebos used?

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3. Mydriasis produced by phenylephrine is not associated with photophobia. Explain why this is so.
4. Why is Mannitol contraindicated in pulmonary edema?
5. What is redistribution of a drug? Explain giving suitable example.
6. What is a spacer? What are its advantages when used with a Metered dose inhaler (MDI)?
7. Why is adrenaline not used in the treatment of congestive cardiac failure despite having a positive ionotropic effect?

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8. What are orphan drugs? Give one example of an orphan drug.
9. Why loperamide is not given in children below five years of age?
10. Describe the mechanism of action of Alteplase.

RAN-3714 ] [1] [?.?.?. ]

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Q.2. Answer any four : 8

1. Compare and contrast Dopamine & Dobutamine.
2. Enumerate parenteral iron preparations. Mention the indications for parenteral iron therapy.
3. Describe in brief the mechanism of action and adverse effects of ACE Inhibitors.
4. Define 'Zero order kinetics' and 'First order kinetics' of drug elimination. With one suitable example describe their clinical importance.

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5. Describe how a mother should be advised to make and administer 'Home made ORS' to a child suffering from mild dehydration.

Section - II

Q.3. Answer any four of the following: 12

1. Explain the mechanism of action and adverse effects of thiazide diuretics.
2. Explain briefly the significance of plasma protein binding.

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3. Describe briefly with preferred agents the clinical uses of prostaglandin analogues.
4. Write the pharmacotherapy of acute bronchial asthma.
5. Write a short note on pharmacotherapy of myasthenia gravis.

Q.4. Answer any two of the following: 10

1. Classify sympathomimetic agents. Describe the therapeutic uses of sympathomimetics with preferred agent for each use you mention.

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2. Classify drugs used for peptic ulcer. Describe in detail drug therapy of peptic ulcer.
3. Enumerate five antihypertensives from different groups. Describe the mechanism and side effects of each drug that you have mentioned.

RAN-3714] [2] [440]

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