Download VNSGU MBBS 2nd Year 2020 July Pharmacology Paper I Question Paper

RAN-3714

Second Year M.B.B.S. Examination

July - 2020

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Pharmacology : Paper - I

Time: 2 Hours ] [ Total Marks: 40

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Fill up strictly the details of signs on your answer book

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Name of the Examination:

Second Year M.B.B.S.

Name of the Subject:

Pharmacology: Paper-1

Subject Code No: 3 7 1 4

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Seat No.:

Student's Signature

Section - I

Q.1. Answer very briefly : 10

1. What is Therapeutic Index? Give two examples of a drug with low therapeutic index.

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2. What is the difference between 'side effect' of a drug and 'toxicity' of a drug? Explain giving an example.
3. How does pH of urine affect elimination of a drug in urine?
4. Explain with reasons whether warfarin can be used for initiation of treatment of deep vein thrombosis.
5. Why is Mannitol contraindicated in pulmonary edema?
6. Why is codeine not recommended for the symptomatic treatment of productive cough?

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7. Why is the subcutaneous route not preferred for administration of adrenaline in anaphylactic shock? Which route is preferred?
8. Give two examples of drugs that can be administered as transdermal patches.

RAN-3714] [1] [P.T.O.]

i) Name the acute reaction with metoclopramide. How is it managed?

j) Although aspirin has a short half life; it is given once a day for its antiplatelet effect. Give justification for the same.

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Q.2. Answer any four : 08

1. What is paradoxical tachycardia produced by quinidine? How can it be prevented?
2. Enumerate two advantages & two disadvantages of second generation antihistaminics over first generation antihistaminics.
3. Enumerate parenteral iron preparations. Mention the indications for parenteral iron therapy.
4. Which drugs are used in triple drug therapy in case of relapse of duodenal ulcer? What is the rationale of using three drugs?

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5. Mention two drugs which should not be withdrawn abruptly, giving reasons for the same.

Section - II

Q.3. Answer any four of the following: 12

1. Describe the treatment of acute congestive cardiac failure.
2. Enumerate Low molecular weight heparins. What are their advantages and disadvantages?

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3. Describe with preferred agent, the clinical uses of prostaglandin analogues.
4. Describe the management of organophosphate poisoning.
5. Classify diuretics. Mention the uses and adverse effects of furosamide.

Q.4. Answer any two of the following: 10

1. Enumerate five antihypertensives from different groups. Describe the mechanism and side effects of each drug that you have mentioned.

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2. Enumerate various ß-blockers. Describe their uses giving the pharmacological basis for each use you mention.
3. Enumerate various drugs from different categories used for the treatment of bronchial asthma. Describe their mechanism of action, preferred route of administration and side effects.

RAN-3714] [2] [90]

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