Download VNSGU MBBS 2nd Year 2020 July Pharmacology Paper II Question Paper

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RAN-3715

Second Year M.B.B.S. Examination

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July - 2020

Pharmacology : Paper - II

Time: 2 Hours ] [Total Marks: 40

? : / Instructions

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Fill up strictly the details of signs on your answer book.

Name of the Examination:

Second Year M.B.B.S.

Name of the Subject:

Pharmacology: Paper - II

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Subject Code No.: 3 7 1 5

Seat No.:

Student's Signature

Section - I

Q.1. Answer very briefly : 10

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1. What is the rationale of using disulfiram in alcohol de-addiction programme?
2. Explain why Penicillin G is lethal to bacterial cell but non toxic to human cells.
3. Describe the difference between antiseptic and disinfectant. Give one example of each.
4. Why is the duration of action of thiopentone sodium very short?
5. What is superinfection? Name one drug that can cause superinfection.

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6. Which is the adverse effect of phenytoin that helps in adjusting its dose?
7. Give two reasons for using propranolol in thyrotoxicosis.
8. What is Mazzoti reaction? How is it managed?
9. Justify: Imipenum is combined with cilastatin for its use in clinical practice.
10. Mention advantages of liposomal amphotericin B.

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RAN-3715] [1] [P.T.O.]

Q.2. Answer any four : 08

1. Write the mechanism of action and side effects of ergotamine in migraine.
2. Enumerate the advantages of human insulin over regular insulin.
3. Give reason why despite a having a short half life, aminoglycosides are effective for long duration.

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4. Explain the pharmacological basis of using morphine in acute LVF.
5. Explain the term 'additive effect' and 'supraadditive effect' in relation to combination of antimicrobials (AMA) giving suitable examples for each.

Section - II

Q.3. Answer any four of the following : 12

1. Describe the drug therapy of hepatic amoebiasis.

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2. Describe how tricyclic antidepressants are beneficial in a case of depression. How does fluoxetine differ from tricyclic antidepressants in this respect.
3. Write a short note on the management of diabetic ketoacidosis.
4. Briefly describe HAART in relation to HIV infection.
5. Describe the mechanism of action, advantages and disadvantages of use of radioactive iodine in hyperthyroidism.

Q.4. Answer any two of the following : 10

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1. Describe the therapeutic uses of glucocorticoids. Mention the adverse effects of prednisolone when used for long term therapy.
2. Describe the pharmacotherapy of Parkinsonism.
3. Describe the drug therapy of P- falciparum malaria.

RAN-3715] [2] [90]

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