[LR 505]
AUGUST 2020
Sub.Code : 5056
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M.B.B.S. DEGREE EXAMINATION
FIRST YEAR
PAPER VI - BIOCHEMISTRY - II
Q.P. Code: 525056
Time: Three hours
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Maximum: 50 Marks
Answer All Questions
I. Essay: (1 x 10 = 10)
- Write in details about the Importance, Applications and Steps of Polymerase Chain Reaction.
II. Write notes on: (5 x 4 = 20)
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- Collagen
- ABG and Interpretation of Results
- Genetic Code
- a) Name the Enzyme defect in Classical phenyl Ketonuria b) Clinical features of PKU c) Name 2 test to detect PKU
- Cytochrome P 450 enzyme systems- Functions and Properties like Induction by drugs
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III. Short answers on: (10 x 2 = 20)
- Name 2 lab test to detect sickle cell disease.
- Name 2 differences of B form and A form DNA
- a) Normal Creatinine clearance value in Adult b) One condition associated with increased Creatinine clearance
- Form of Folie Acid involved in Purine Synthesis
- a) Normal reference range of a) Blood Urea b) Serum Creatinine c) Urea / Creatinine Ratio d) 24 hours urinary excretion of creatinine in adult.
- a) Expand RFLP b) Clinical uses of RFLP
- Name 2 markers of obstructive of Jaundice.
- Name 2 post translational modification
- Name 2 Antioxidant enzymes
- a) Mineral Required for DNA Polymerase activity b) Rifampian Blocks of Transcription process.
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