[KZ 504]
AUGUST 2011
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Sub. Code: 4055
FIRST M.B.B.S. DEGREE EXAMINATION
Revised (Non-Semester) Regulations
PAPER V - BIOCHEMISTRY - I
Q. P. Code: 524055
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Time: Three hours
Maximum: 100 Marks
Answer ALL questions
I. Essay Questions : (2 x 10 = 20)
- Describe in detail TCA cycle and the energetics of the same. Justify why TCA cycle is called an amphibolic cycle.
- Describe in detail the components and chemiosmotic theory of electron transport chain.
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II. Write Short notes on : (10 x 5 = 50)
- Role of Niacin as Coenzyme.
- Classification of hyperlipidemias and their clinical importance.
- Sphingolipidoses.
- Biochemical role of Vitamin C.
- Cori's cycle and Glucose Alanine cycle.
- High Density Lipoprotein cycle.
- Glycogenolysis.
- Isomerism in carbohydrates.
- Balanced Diet.
- Fructose intolerance.
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III Short Answer Questions : (15 x 2 = 30)
- Markers for lysosomes and mitochondria.
- Fluorosis.
- Role of Apo CII.
- Define metalloenzymes with 2 examples.
- Pulmonary surfactant - Structure and clinical importance.
- Iodine number and its importance.
- What is the function of Lipoprotein lipase?
- Structure of lecithin.
- Net Protein Utilization.
- Chondroitin sulphate - Structure.
- Double Reciprocal plot.
- Alkaline phosphatase as a diagnostic tool.
- What are the different forms of calcium in blood?
- RDA and functions of Iodine.
- Why Arachidonic acid is not considered 'purely' an essential fatty acid?
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