Download MBBS 1st Year 2008 August 524056 Biochemistry II Question Paper

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[KT 505]

AUGUST 2008

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Sub. Code: 4056

FIRST M.B.B.S. DEGREE EXAMINATION

Revised (Non-Semester) Regulations

PAPER VI – BIOCHEMISTRY - II

Q. P. Code: 524056

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Time: Three hours

Maximum: 100 Marks

Answer ALL questions.

Draw Suitable diagrams wherever necessary

I. Essay Questions : (2 x 15 = 30)

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1. Describe the pathways of methionine metabolism. Add a note on metabolic functions of methionine and cysteine.
2. Describe the biosynthesis of purine nucleotide. Add a note on regulation.

II. Write Short notes on : (10 x 5 = 50)

1. Transamination reactions.
2. Renal regulation of pH.

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3. Gout.
4. Mutation.
5. Differences between DNA and RNA.
6. Oncogenes.
7. Post translational modification.

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8. Formation of creatine.
9. Alkaptonuria.
10. Southern blotting.

III. Short Answer Questions : (10 x 2 = 20)

1. Name the buffer systems of blood.

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2. Sources of carbon and nitrogen in purine ring.
3. Wobble hypothesis.
4. Write the enzyme defect in (1) Lesch-Nyhan Syndrome (2) Orotic aciduria.
5. Okasaki fragments.
6. What are Xenobiotics.

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7. Causes of Metabolic acidosis.
8. Name the important compounds formed from Glycine.
9. Inhibitors of protein biosynthesis.
10. Apoptosis.

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