[LB 544]
AUGUST 2012
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Sub. Code: 4065
SECOND M.B.B.S. DEGREE EXAMINATION
Paper I - PHARMACOLOGY - I
Q. P. Code: 524065
Time: 180 Minutes
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Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on:
| Pages (Max.) | Time (Max.) | Marks (Max.) | |
|---|---|---|---|
| 1. a. Classify the drugs used as peripherally acting skeletal muscle relaxants. b. Discuss in detail the pharmacological actions and toxicity produced by d-Tubocurarine. c. Add a note on the rationale of using Dantrolene sodium in the management of Malignant Hyperthermia. | 16 | 30 | 10 |
| 2. Discuss the role of sympathomimetics in the management of Bronchial asthma. | 8 | 20 | 5 |
II. Write notes on:
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- Drug responses in elderly. 3 8 1.5
- Uroselective a adrenergic blockers. 3 8 1.5
- Selective 5-HT 1B/1D agonist. 3 8 1.5
- Mechanism of action and uses of Nimesulide. 3 8 1.5
- Propofol as an inducing agent. 3 8 1.5
- Role of Ethyl alcohol in Methyl alcohol poisoning. 3 8 1.5
- Management of Status Epilepticus. 3 8 1.5
- Malignant Neuroleptic Syndrome. 3 8 1.5
- Contraindications for Digitalis use. 3 8 1.5
- Mechanism of action and uses of Spironolactone. 3 8 1.5
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III. Short answers on:
- Citrovorum factor rescue. 2 5 1
- Heparin Antagonist. 2 5 1
- 4 extravascular uses of Clonidine. 2 5 1
- Physiological Antagonism. 2 5 1
- Dopaminergic agonist in Parkinsonism. 2 5 1
- Uses of Diazepam. 2 5 1
- Contraindications for ß blockers. 2 5 1
- Mechanism of action and uses of Nitrendipine. 2 5 1
- Consequences of Microsomal inhibition. 2 5 1
- Bupivacaine. 2 5 1
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