[LE 542]
FEBRUARY 2014
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Sub. Code: 4063
SECOND YEAR MBBS DEGREE EXAMINATION
Paper V - GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code: 524063
Time: Three Hours
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Maximum: 40 Marks
Answer ALL questions.
Draw Suitable diagrams wherever necessary
I. Elaborate on: (2 x 7.5 = 15)
- Define thrombosis, write in detail about pathogenesis, causes, morphology and fate of thrombus.
- 40 yr old male presented with h/o fever, vomiting and diarrhoea. Patient had temperature of 103 degrees F. Weak rapid pulse, hypotension, tachypnoea, cold, clammy, cyanotic skin. Blood culture gram negative bacterial infection positive.
- What is your diagnosis?
- Explain the pathogenesis and morphology.
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II. Write Notes on: (10 x 1.5 = 15)
- Definition and characteristics of types of necrosis.
- Phagocytosis.
- Paraneoplastic syndromes.
- Gaucher's disease.
- Hypersensitivity reaction II
- Morphological changes in apoptosis.
- Vascular events in acute inflammation.
- Chemokines.
- Morphology of infarct.
- Opportunistic infections in AIDS.
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III. Short Answers on: (10 x 1 = 10)
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- Write any two stem cell niches.
- Heinz bodies.
- Types of leprosy.
- Mention the cause of thrombocytopenia.
- Bart haemoglobin.
- Types of wound healing.
- Two inherited disorders of platelets.
- Two oncogenic DNA virus.
- Two tumor suppressor genes.
- Two examples of acute phase proteins.
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