RUHS FIRST YEAR MBBS EXAMINATION
BIOCHEMISTRY- PAPER - I
Jan/Feb 2015 TIME: 3 HOURS TOTAL MARKS: 50
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INSTRUCTIONS:
- Que. No. 1 and 5 in section A and B are compulsory. Attempt ANY TWO questions from rest of the questions in each section.
- Use separate answer sheet for each section.
Section A
Q1. Discuss the alternative pathways for glucose oxidation and their significance. 10
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Q2. Describe in details
- Role of physiological uncoupling proteins in health and disease.
- Ketogenesis and its regulation
Q3.
- How urea is synthesized in body? Discuss its inherited metabolic defects
- Describe catabolism of purines and discuss associated metabolic disorders.
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Q4. Discuss briefly
- Carnitine shuttle
- PEM
- Competitive inhibition
- Homocystinuria
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SECTION B
Q5. Describe the chemistry, sources & daily requirements, functions and deficiency disorders of vitamin A.
Q6. a) Discuss role of different hormones in the regulation of blood glucose
- Describe biochemical and clinical features in different types of porphyrias
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Q7. a) Describe ETC and its inhibitors
- Discuss absorption and metabolism of iron
Q8. Write short notes on
- Folate antagonists
- Balanced diet
- Fluorosis
- Antioxidants
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