Download RUHS MBBS 1st Year 2015 Feb Biochemistry Paper II Question Paper

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RUHS FIRST YEAR MBBS EXAMINATION

BIOCHEMISTRY- PAPER - II

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Jan/Feb 2015 TIME: 3 HOURS TOTAL MARKS: 50

INSTRUCTIONS:

1. Que. No. 1 and 5 in section A and B are compulsory. Attempt ANY TWO questions from rest of the questions in each section.
2. Use separate answer sheet for each section.

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Section A

Q1. Describe recombinant DNA technology and its application.

Q2. Describe in detail

1. Post-translational modification.
2. Diseases related to DNA damage

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Q3. a) Discuss salient features of codons

b) Discuss Gene therapy & its applications

Q4. Discuss briefly

1. Multiple Myeloma
2. Greenhouse effect

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3. Tumor suppressor genes
4. Cytochrome P- 450

SECTION B

Q5. Discuss regulation of gene expression in prokaryotes with suitable example

Q6. a) Discuss disorders of Acid Base Balance

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b) Discuss allergy and hypersensitivity

Q7. a) Biochemical tests employed for the differential diagnosis of Jaundice

b) Discuss transmission & lab diagnosis of AIDS

Q8. Differentiate between

1. Mutation and polymorphism

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2. Southern and western blotting
3. Gene cloning and PCR
4. ELISA and RIA

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