Download RUHS MBBS 2nd Year 2016 January Pharmacology Paper I Question Paper

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RUHS Second MBBS (Main) Examination

Pharmacology Paper -I Date: January 2016 Time: 3 hours Max Marks: 40

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Instructions: Attempt all questions. (Use separate answer sheet for each section)

SECTION A

1. Classify drugs used in bronchial asthma. Discuss mechanism of action, adverse effects & clinical status of beta 2 agonist.(A. 223, B. 357) (08)

2. Explain why: (4 x3 = 12)

a) Neostigmine is preferred over physostigmine for the treatment of myasthenia gravis.(A. 120, B. 295)

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b) Benzodiazepines (BZDs) are preferred over barbiturates as sedative hypnotics. (A. 401, 113)

c) Ethanol is used for treatment of methanol poisoning(A. 395, B. 93)

d) Levodopa L-DOPA) is combined with carbidopa(A. 429, B. 228)

SECTION B

3. Write short notes on;

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a) Spinal anaesthesia (A. 369, B.240)

b) Proton pump inhibitors (A. 651,B. 621)

c) Drug antagonism (A. 57, B. 38)

4. Give the suitable answer for the following; (1 x 10 = 10)

a) Enumerate mydriatics. Write their two uses(A. 118, B. 1028)

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b) Define tachyphylaxis. Give suitable examples(A. 70, B. 60)

c) Enumerate methods of prolongation of drug action.

d) Write advantages of second generation anti-histaminics over first generation.(A. 166, B. 320, 324)

e) Define pharmacogenetics with suitable examples. (A. 65, B. 58)

f) Name disease modified antirheumatic drugs. (DMARDs)(A. 210, B. 1039)

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g) Write advantages of sublingual route of drug administration. Name the drugs given by this route

h) Write the drugs used as pre anaesthetic medication. (A. 118, 386, B. 105)

i) Define bio availability. Mention its clinical significance. (A. 16, B. 11)12)

j) Write advantages & disadvantages of fixed dose combination (FDC) of drugs. (A.62)

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