Download RUHS MBBS 2nd Year 2017 January Pharmacology Paper II Question Paper

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RUHS Second MBBS (Main) Examination

Pharmacology Paper -II Date: January 2017 Time: 3 hours Max Marks: 40

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Instructions: Attempt all questions. (Use separate answer sheet for each section)

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SECTION A

1. Answer the following; (08)
   1. Explain the mechanism of action of fluoroquinolones as antimicrobials(A.709, B. 647)
   2. What are Lepra reactions? How are they treated? (A. 786, 761)

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   3. What is the rationale for combining Ampicillin with Sulbactam?(A. 724, B.665)
   4. Enumerate important uses of Metronidazole. (A. 837, B. 784)
2. Explain why: (4 x2=8)
   1. What are the uses of Oral Iron Preparations?(A. 604, B. 496)
   2. Differentiate between Heparin & Warfarin. (A. 624, B. 474)

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   3. Explain the therapeutic use of Oxytocin(A. 329, B. 630)
   4. Explain the rationale of Combining Furosemide with Spironolactone. (A.588, B. 556)
3. Describe the mechanism of action, therapeutic, uses and adverse effects of Angiotensin converting enzyme inhibitors. (A. 500,13. 421) (4)

SECTION - B

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4. Give the suitable answer for the following; (2 x 10 = 10)
   1. Write a note on newer insulin.(A.263, B. 882)
   2. What is HPA Axis Suppression while using Glucocorticoids? Write measures to reduce it.(A. 294, B. 914)
   3. Enumerate selective Estrogen receptor modulators & give their uses. (A.313, B. 939)
   4. Enumerate difference between Carbimazole and Propylthiouracil as antithyroid drugs(A. 25 4, B. 871)
   5. Explain the mechanism of action of combined oral contraceptive pills(A. 323,11 952)

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   6. What is the pharmacological basis of using Glyceryl trinitrate for treatment of angina pectoris? (A. 542, B. 393)
   7. What are the chelating agents? Give two examples (A. 906, B. 1049)
   8. Explain the mechanism of action of Digoxin in treatment of Congestive Cardiac failure(A. 517, B. 445)
   9. Why is Pyridoxine given to patients who are on treatment with isoniazid. (A.776, B. 740)
   10. Discuss the chemoprophylaxis of Malaria(A. 820, B. 765)

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