Download RUHS MBBS 2nd Year 2018 February Pharmacology Paper I Question Paper

www.FirstRanker.com www.FirstRanker.com

RUHS Second MBBS (Main) Examination

Pharmacology Paper -I Date: February 2018 Time: 3 hours Max

--- Content provided by‍ FirstRanker.com ---

Marks: 40

Instructions: Attempt all questions. (Use separate answer sheet for each section)

************************************************************************

SECTION A

1. Enumerate the factors modifying drug action. Explain how liver function, kidney function, cardiac disease and thyroid status modify drug action giving suitable examples. (08)

--- Content provided by​ FirstRanker.com ---

2. Write short notes on (3 x 2 = 6)
   1. Atypical antidepressants(A. 441, B. 195)
   2. Proton pump inhibitors(A. 651, B. 621)
   3. Prostaglandin analogues in treatment of glaucoma(A. 154, B. 1030)
3. Write short notes on;
   1. Moderately severe asthma (A. 232, B. 361)

   --- Content provided by FirstRanker.com ---

   2. Organophosphorous poisoning(A. 110, B. 289)
   3. Migraine

SECTION B

4. Give the suitable answer for the following; (1 x 10 = 10)
   1. Advantages of phosphenytoin over phenytoin(A. 413, B. 127)

   --- Content provided by​ FirstRanker.com ---

   2. Role of placebo in medicine
   3. Clinical implications of zero order kinetics.(A. 31, B. 23)
   4. Levodopa and not dopamine is used in the treatment of Parkinsonism.(A.426, B. 231)
   5. Advantages of 2nd generation antihistaminics over 1st generation antihistaminics.(A. 166, B. 320) Clinical implications of microsomal drug infection.(A. 26, B. 30)
   6. Mechanism of action of lignocaine.(A. 361, B. 241)

   --- Content provided by​ FirstRanker.com ---

   7. Role of sucralfate in therapy of peptic ulcer
   8. Some drugs require therapeutic drug monitoring.(A. 34, B. 24)
   9. Paediatric preparations of tetracyclines are not available in the market.(A.778, B. 689)

www.FirstRanker.com

--- Content provided by​ FirstRanker.com ---