Download KUHS MBBS 2nd Year 211001 January 2023 Pharmacology Paper I Question Paper

Q.P. Code: 211001                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               & www.FirstRanker.com

2019 Scheme

Second Professional MBBS Degree Regular/Supplementary
Examinations January 2023

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Pharmacology - Paper I
(General Pharmacology, ANS, CNS, CVS, Blood, Diuretics, Autacoids, Respiratory System)
Time: 3 Hours                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  &p>

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Long Essays

1. (a) Classify drugs used for treatment of epilepsy with two examples each.
   

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   (b) Write the mechanism of action, uses and adverse effects of sodium valproate.
   (c) Outline the management of status epilepticus. (2x15=30)
2. A 65-year-old woman presents with swelling over ankle and feet and over the face in morning. Weakness, fatigue, cough at night. A diagnosis of moderate heart failure is made by physician
   (a) Enumerate four drug groups with two examples each to treat heart failure.
   (b) Describe the rationale for using each drug group.
   

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   (c) Mention the other uses and adverse effects of ACE Inhibitors. (6+4+5)

Short essays

1. (a) Classify peripherally acting skeletal muscle relaxants.
   (b) Mention one centrally acting skeletal muscle relaxant with its mechanism of action and indications for use. (5x8=40)
2. Briefly describe kinetics of elimination. Add a note on factors modifying drug action. (4+4)
3. (a) Signs and symptoms of Atropine toxicity. Briefly outline the management.
   

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   (b) Uses of Prostaglandins (4+4)
4. (a) Frusemide.
   (b) Write the pharmacological management of Stage II Hypertension. (4+4)
5. Heparin. (4+4)

Short answers

1. Pharmacological management of Opium (Morphine) dependence. (2+3+3)

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2. Enumerate four therapeutic uses of Adrenaline, with its rationale for use in each condition. (5x4=20)
3. Propofol.
4. Pharmacotherapy of Rheumatoid arthritis.
5. Anxiety disorders.

Choose the Appropriate Drug and Justify:

1. Adrenaline/Noradrenaline in Anaphylactic shock

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2. Levodopa/Benzhexol in chlorpromazine induced Parkinsonism (2x1=2)

Name the following (Two examples for each):

1. Drugs used in productive cough
2. Centrally acting alpha-2 receptor agonists.
3. Microsomal enzyme inhibitors
4. Xanthine oxidase inhibitors

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5. Vasicoselective anticholinergics.
6. Carbonic anhydrase inhibitors in glaucoma
7. Drugs causing tachyphylaxis
8. Drugs used to treat Acute Mania. (8x1=8)

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