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2019 Scheme
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Q.P. Code: 211001Reg. no.:
Second Professional MBBS Degree Supplementary Examinations
July 2023
Pharmacology - Paper I
(General Pharmacology, ANS, CNS, CVS, Blood, Diuretics, Autacoids, Respiratory System)
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Time: 3 HoursTotal Marks: 100
- Answer all questions to the point neatly and legibly. Do not leave any blank pages between answers
- Indicate the question number correctly for the answer in the margin space
- Answer all parts of a single question together. Leave sufficient space between answers
- Draw table/diagrams/flow charts wherever necessary
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Long Essays (2x15=30)
- A 52-year-old man presented with complaints of tightness and discomfort in middle part of chest, particularly after brisk walking. This is relived within 10 minutes of rest. A diagnosis of Angina pectoris was made by physician after appropriate investigations.
- Mention four different drug groups used in treatment of Angina with two examples each.
- Write the mechanism of action and adverse effects of Nitrates.
- Outline the management of Acute pulmonary edema, with rationale for use of each drug.
- Briefly describe Antiplatelet drugs. (4+3+4+4)
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- A 29-year employee gradually stopped going out, withdrew socially. He felt guilty, worthless and tired all time, lost interest in pleasure and sex and had disturbed sleep. Physician diagnosed him a case of Major depression.
- Enumerate three drug groups with two examples each to treat major depression.
- Write the mechanism of action, uses and adverse effects of Fluoxetine.
- Briefly describe Atypical Antipsychotics (5+5+5)
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Short essays (5x8=40)
- Briefly describe drug biotransformation. Describe microsomal enzyme induction. (4+4)
- Aspirin.
- Classify Diuretics. Briefly describe Frusemide. (4+4)
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- Outline the management of Organophospherous poisoning.
- Write the mechanism of action, therapeutic uses and adverse effects of Pancuronium. (4+4)
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- Briefly describe Adrenaline, Advantage of combining Adrenaline with Lignocaine. Mention the sites where this combination is contraindicated. (4+3+1)
Short answers (5x4=20)
- Pharmacological management of Bronchial Asthma.
- Streptokinase.
- Pharmacotherapy of Alcohol dependence.
- What is the rationale of using Beta-blockers in Glaucoma.
- Therapeutic uses of Anti-histamines.
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Choose the Appropriate Drug and Justify: (2x1=2)
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- Codein / Bromhexine in dry cough.
- Alpha Methyl Dopa / Losartan in pregnancy induced hypertension.
Name the following (Two examples for each): (8x1=8)
- Drugs used in Absence seizures.
- Prodrugs.
- Drugs used to treat Bipolar illness.
- Drugs administered transdermally.
- Drugs used to treat Morphine poisoning.
- Uricosuric agents.
- Prostaglandin analogues.
- Aldosterone antagonist.
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