Download KUHS MBBS 2nd Year 202001 May 2022 Pharmacology Paper II Question Paper

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2010 Scheme

Q.P. Code: 202001 Reg. no.: .....................

Second Professional MBBS Degree Supplementary Examinations May 2022

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Pharmacology - Paper II

Time: 2 Hours Max. Marks: 40

• Answer all questions to the point neatly and legibly. Do not leave any blank pages between answers. Indicate the question number correctly for the answer in the margin space
• Answer all parts of a single question together. Leave sufficient space between answers
• Draw table/diagrams/flow charts wherever necessary

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Essays (2x6=12)

1. Classify Thyroid inhibitor drugs. Describe the mechanism of action, and adverse effects of carbimazole. Explain the role of iodides in hyperthyroidism. (2+2+2)
2. A 40 years old female patient admitted to hospital with a complaint of fever with chills and right loin pain since 5 days. She is a known diabetic. Urine microscopy shows plenty of pus cells and gram negative bacilli. Her serum creatinine is moderately elevated. Ultra sonogram of abdomen suggestive of acute pyelonephritis of right kidney.
   • List four groups of drugs with example, useful against gram negative organisms
   • Explain the mechanism of action and two adverse effects of each group
   • Describe the mechanism of action of Fluoroquinolones

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   • Mention the antibiotics to be avoided for the above patient (2+2+1+1)

Short Notes (5x3=15)

3. Cotrimoxazole
4. Doxycycline

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5. Alkylating agents
6. Metoclopramide
7. Short acting insulin analogues

Write the Pharmacological basis for the use of: (3x1=3)

8. Cilastatin with Imipenem

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9. Primaquine in plasmodium vivax malaria
10. Finasteride in benign prostatic hypertrophy

Write two uses and two adverse effects of the following: (3x1=3)

11. Albendazole
12. Rifampicin

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13. Dimercaprol

Choose the appropriate drug and Justify: (2x1=2)

14. Glibenclamide/Glipizide in elderly patients
15. Combined pill/Mini pill as oral contraception

Name the following (Two examples for each) (5x1=5)

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16. Selective estrogen receptor modulators
17. Neuraminidase inhibitors
18. Luminal amoebicides
19. Bisphosphonates used in postmenopausal Osteoporosis.
20. Antimotility drugs used in nonspecific diarrhoeas

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