FirstRanker Logo

FirstRanker.com - FirstRanker's Choice is a hub of Question Papers & Study Materials for B-Tech, B.E, M-Tech, MCA, M.Sc, MBBS, BDS, MBA, B.Sc, Degree, B.Sc Nursing, B-Pharmacy, D-Pharmacy, MD, Medical, Dental, Engineering students. All services of FirstRanker.com are FREE

📱

Get the MBBS Question Bank Android App

Access previous years' papers, solved question papers, notes, and more on the go!

Install From Play Store

Download MBBS 2nd Year Pharmacology Paper I Important Questions

Download MBBS (Bachelor of Medicine and Bachelor of Surgery) 2nd Year Pharmacology Paper I Important Questions (Question Bank)

This post was last modified on 19 June 2021

MBBS 2nd Year (Second Year) Important Questions (Question Bank)


FirstRanker.com

MBBS Second Year Pharmacology Paper-I Important Question Bank

Essay Questions:

--- Content provided by FirstRanker.com ---

  1. Classify anti-hypertensive drugs. Discuss in detail about the management of hypertensive emergency and urgency. Which anti-hypertensives are to be avoided in pregnancy and Why?
  2. a) Define Biotransformation reaction. b) Explain phase I and phase II reaction with suitable examples. c) Importance of Enzyme induction and enzyme inhibition.
  3. a) Classify Anticonvulsant drugs. b) Mechanism of action and pharmacological action of Benzodiazipines. c) Therapeutic uses and adverse effects of Benzodiazipines.
  4. i) Define drug and dose. ii) Factors modifying drug action.
  5. i) Classify antiepileptic drugs with examples for each group. ii) Describe mechanism of action, adverse effects and therapeutic indications of Diphenyl hydantoin. iii) Role of Topiramate in epileptic patients.
  6. --- Content provided by⁠ FirstRanker.com ---

  7. (i) Classify antihypertensive drugs. (ii) Discuss the mechanism of action & therapeutic uses of Angiotensin receptor blockers. (iii) Outline briefly about hypertensive emergencies and urgencies.
  8. (i) Classify adrenergic drugs. (ii) Discuss the therapeutic uses of adrenergic drugs. (iii) Outline the adverse effects and contraindications of Adrenaline.
  9. (i) Classify anticholinersterases (ii) Discuss the mechanism of action and indications of reversible anti-cholisterases (iii) Outline the management of acute organophosphorous poisoning.
  10. (i) Enumerate the various sedative and hypnotic drugs. (ii) Discuss the mechanism of action, uses and adverse effects of benzodiazepines. (iii) Briefly discuss the management of acute barbiturate poisoning.
  11. a) Classify antiepileptic drugs. b) Discuss in detail about the mechanism of action, kinetics, adverse effects and uses of phenytoin. c) How will you manage a known epileptic with three months of enorrhoea.
  12. --- Content provided by‍ FirstRanker.com ---

  13. a) Classify ß blockers. b) Discuss the pharmacological actions, kinetics, adverse effects and Usesof propronalol. c) Mention the role of beta blockers in thyrotoxicosis.
  14. Discuss the role of sympathomimetics in the management of Bronchial asthma.
  15. a. Classify the drugs used as peripherally acting skeletal muscle relaxants. b. Discuss in detail the pharmacological actions and toxicity produced by d-Tubocurarine. c. Add a note on the rationale of using Dantrolene sodium in the management of Malignant Hyperthermia.
  16. a. Classify antiparkinsonian drugs. b. Write about on Dopaminergic agonists.
  17. a. Classify adrenergic drugs based on therapeutic uses. b. Discuss about the pharmacological action adverse effects and uses of adrenaline.
  18. --- Content provided by​ FirstRanker.com ---

  19. Discuss the drug therapy of Anticholinesterase poisoning.
  20. a) Classify the drugs used for the treatment of Parkinsonism. b) Discuss the Pharmacological actions, Adverse effects & Interactions of Levodopa.
  21. a) Classify antianginal drugs. b) Discuss the mechanism of action and therapeutic uses of Glyceryl trinitrate.
  22. a) Classify Diuretics b) Discuss the mechanism of action, therapeutic uses and complications of Frusemide.
  23. Enumerate antiepileptic drugs. Discuss the pharmacology of drugs acting on GABA receptors.
  24. --- Content provided by​ FirstRanker.com ---

  25. Define Biotransformation. Describe briefly the various biotransformation reactions.
  26. Classify Non-steroidal anti inflammatory drugs. Write the mechanism of action, pharmacological actions, therapeutic uses and adverse effects of Salicylates.
  27. Discuss various factors modifying a drug's actions. Write briefly about Pharmacogenetics.
  28. Classify Sedative - Hypnotics. Discuss the mechanism of action, uses and adverse effects of Benzodiazepines. Write briefly on Flumazenil.
  29. Classify beta blockers. Mention the advantages of selective over non selective beta blockers. Discuss the adverse effects of beta blockers.
  30. --- Content provided by⁠ FirstRanker.com ---

  31. Classify antianginal drugs. Discuss the mechanism of action, uses and adverse effects of nitrates.
  32. Classify drugs used in the treatment of parkinsonism. Explain the mechanism of action and adverse effects of levodopa. What is the rationale for use of carbidopa with levodopa? Write briefly on selegiline.
  33. Classify anti-epileptic drugs. Discuss the mechanism of action, adverse effects and therapeutic uses of phenytoin. Briefly discuss the drug therapy of status epilepticus.
  34. Classify anti-arrhythmic drugs. Write in detail about mechanism of action, pharmacokinetics, clinical uses and adverse effects of amiodarone.
  35. Classify anti-hypertensive drugs. Discuss the adverse effects and therapeutic uses of beta blockers. Discuss the drug therapy of hypertensive emergency.
  36. --- Content provided by⁠ FirstRanker.com ---

  37. A 45 year old male patient is brought to the emergency with c/o seizure episode associated with loss of consciousness. He is a known epileptic for past 2 years with history of recurrent tonic clonic seizures. a. Enumerate the drugs used in treatment of Epilepsy. b. Discuss in detail the pharmacology of Valproic acid. c. Write briefly on the management of Status Epilepticus

Short Answer Questions:

  1. Local routes
  2. Treatment of Glaucoma
  3. Balance anaesthesia
  4. --- Content provided by⁠ FirstRanker.com ---

  5. Selective serotonin re-uptake inhibitors
  6. Osmotic diuretics
  7. Caverdilol
  8. Mechanism of action and uses of antiplatelet drugs
  9. Atarvostatin
  10. --- Content provided by‌ FirstRanker.com ---

  11. Iron preparations and uses
  12. Pre-anesthetic medication
  13. Pro drug
  14. Rationale for use of dopamine in cardiogenic shock
  15. Therapeutic range
  16. --- Content provided by‍ FirstRanker.com ---

  17. Controlled release drugs
  18. Postural hypotension
  19. Zero order kinetics
  20. Mast cells modulators
  21. Mucolytic drugs
  22. --- Content provided by‌ FirstRanker.com ---

  23. Dissociative anesthesia
  24. COX-Inhibitors
  25. Mention four drugs bound to plasma albumin
  26. What is Rupatadine? Mention one indication for it
  27. Mention two Leukotriene antagonists used in bronchial asthma
  28. --- Content provided by‌ FirstRanker.com ---

  29. What is fomepizole? Mention one indication for it
  30. Mention any four preanaesthetic medicants
  31. Mention four angiotensin receptor blockers
  32. Drugs used in anaphylactic shock
  33. Mention two non benzodiazepine hypnotics
  34. --- Content provided by‌ FirstRanker.com ---

  35. Mention two selective dopamine agonists used in Parkinson's disease
  36. Give two examples for physiological functional antagonism
  37. Classification and therapeutic uses of a (Alpha) - blockers
  38. Pharmacotherapy of migraine
  39. Thiazide diuretics - Mechanism of action, adverse effects and uses
  40. --- Content provided by​ FirstRanker.com ---

  41. Drug therapy of chronic gout
  42. Heparin - mechanism of action, adverse effects and indications
  43. Therapeutic uses of prostaglandins
  44. Treatment of organophosphorus poisoning
  45. Drugs to be avoided in elderly and their safer alternatives
  46. --- Content provided by⁠ FirstRanker.com ---

  47. Treatment of Myocardial infarction
  48. Enumerate statins Write about mechanism of action and indications of statins
  49. Newer drug delivery system
  50. Therapeutic uses of atropine and its substitutes
  51. Therapeutic uses of H antihistaminics
  52. --- Content provided by⁠ FirstRanker.com ---

  53. Centrally acting skeletal muscle relaxants
  54. Complications of spinal anaesthesia
  55. Phenytoin sodium
  56. Amiodarone
  57. Flurosemide
  58. --- Content provided by​ FirstRanker.com ---

  59. Heparin
  60. Mast cell stabilizers
  61. Mention four drugs delivered by transdermal patches
  62. Define Plasma half life Mention two drugs with long Plasma half life
  63. Mention four methods of prolongation of drug action
  64. --- Content provided by FirstRanker.com ---

  65. What is competitive antagonism?
  66. Define Teratogenicity Mention four Teratogenic drugs
  67. Mention four drugs used in the treatment of Glaucoma
  68. Mention four therapeutic uses of Prostaglandins
  69. Mention four contraindications for Aspirin
  70. --- Content provided by FirstRanker.com ---

  71. Give four examples for DMARDs
  72. Mention four examples for HMG-CoA reductase inhibitors
  73. Mechanism of action of Disulfiram
  74. What is potentiation of drug action? Mention two examples?
  75. What is Eutetic mixture? Mention its indications
  76. --- Content provided by‌ FirstRanker.com ---

  77. Mention two uses, two advantages and two disadvantages of thiopentone sodium
  78. What is first order kinetics?
  79. What is fixed dose combination? Give two examples
  80. Mention two selective Cox- inhibitors What are the advantages?
  81. What are antitussives? Give two examples
  82. --- Content provided by FirstRanker.com ---

  83. Mention thiazide diuretics Mention two uses of thiazides
  84. What is the mechanism of action and uses of Montelukast?
  85. Mydriatics
  86. Drugs used in prophylaxis of migraine
  87. Receptor antagonism of drugs
  88. --- Content provided by‌ FirstRanker.com ---

  89. Sublingual route of administration
  90. Blood-Brain barrier
  91. Therapeutic uses of loop diuretics
  92. Parenteral iron therapy
  93. Epsilon amino-caproic acid
  94. --- Content provided by FirstRanker.com ---

  95. Therapeutic uses of prostaglandin analogues
  96. Uricosuric agents
  97. Essential drugs
  98. Microsomal enzyme inducers
  99. Antagonism
  100. --- Content provided by​ FirstRanker.com ---

  101. Pre anesthetic medication
  102. Therapeutic uses of morphine
  103. Treatment of Alzheimers disease
  104. Glyceryl trinitrate
  105. Inhaled steroids
  106. --- Content provided by⁠ FirstRanker.com ---

  107. Lignocaine
  108. Osmatic diuretics
  109. Define pharmacogenomics
  110. Orphan drugs
  111. Mechanism of action of digoxin
  112. --- Content provided by‌ FirstRanker.com ---

  113. Loading dose
  114. First dose effect
  115. Name two sialogoges
  116. Drugs used in acute gout
  117. Mention four Atypical anti psychotics
  118. --- Content provided by‌ FirstRanker.com ---

  119. Mention two uses of Dinoprostone
  120. Name two central sympatholytic agents write two uses
  121. Citrovorum factor rescue
  122. Heparin Antagonist
  123. extravascular uses of Clonidine
  124. --- Content provided by‍ FirstRanker.com ---

  125. Physiological Antagonism
  126. Dopaminergic agonist in Parkinsonism
  127. Uses of Diazepam
  128. Contraindications for ß blockers
  129. Mechanism of action and uses of Nitrendipine
  130. --- Content provided by​ FirstRanker.com ---

  131. Consequences of Microsomal inhibition
  132. Bupivacaine
  133. Drug responses in elderly
  134. Uroselective a adrenergic blockers
  135. Selective -HT B/D agonist
  136. --- Content provided by​ FirstRanker.com ---

  137. Mechanism of action and uses of Nimesulide
  138. Propofol as an inducing agents
  139. Role of Ethyl alcohol in Methyl alcohol poisoning
  140. Management of Status Epilepticus
  141. Malignant Neuroleptic Syndrome
  142. --- Content provided by⁠ FirstRanker.com ---

  143. Contraindications for Digitalis use
  144. Mechanism of action and uses of Spironolactone
  145. What is cumulation
  146. Drug therapy for vertigo
  147. Omalizumab
  148. --- Content provided by‍ FirstRanker.com ---

  149. Therapeutic Index
  150. Modafinil
  151. Amakacin
  152. Uses Erthropoietin
  153. Name four Angiotensin Receptor blockers
  154. --- Content provided by​ FirstRanker.com ---

  155. Esmolol
  156. Mention four adverse effects of Phenytoin
  157. Fixed dose ratio combinations
  158. Newer drug delivery system
  159. Pentazocine
  160. --- Content provided by‌ FirstRanker.com ---

  161. Potassium channel Openers
  162. Therapeutic use of atropine
  163. Adverse effect of high ceiling diuretics
  164. Mention the various Iron Preparation
  165. Seletive serotonin Reuptake inhibitors
  166. --- Content provided by⁠ FirstRanker.com ---

  167. Venodilators
  168. Metachlopromide
  169. Specialized active transport mechanism across biological membrane
  170. Beneficial effects of ß blockers in Myocardial infarction
  171. Topiramate
  172. --- Content provided by‌ FirstRanker.com ---

  173. Effects of Aspirin on acid base & electrolyte balance
  174. Mucokinetic agents
  175. Local anaesthetics in the presence of inflammation
  176. Aldehyde dehydrogenase inhibitor
  177. Agents inhibiting Renin-Angiotensin system
  178. --- Content provided by⁠ FirstRanker.com ---

  179. Pharmacovigilance
  180. Glycoprotein IIb/Illa receptor antagonist
  181. merits & demerits of rectal administration of drugs
  182. Sibutramine
  183. Advantages of topical ß blockers over miotics in Glaucoma
  184. --- Content provided by​ FirstRanker.com ---

  185. Uses of Cyproheptadine
  186. Name Leukotriene receptor antagonists & their indications
  187. Thiazides as Antidiuretics
  188. Azelastine
  189. Adenosine in the management of Paroxysmal Supra Ventricular Tachycardia
  190. --- Content provided by‌ FirstRanker.com ---

  191. What are LMW Heparins & enumerate their advantages over regular Heparin
  192. Serotonin and Noradrenaline Reuptake Inhibitors (SNRI)
  193. Mention four antiasthmatic drugs
  194. Enumerate four routes of drug administration
  195. Mention four anti psychotic drugs
  196. --- Content provided by FirstRanker.com ---

  197. Define anaphylaxis with a suitable example
  198. Mention four contraindication for morphine
  199. Mention four drugs for Gout
  200. Give two examples of drugs administered by Transdermal route
  201. Enumerate the methods for prolongation of drug action
  202. --- Content provided by⁠ FirstRanker.com ---

  203. Explain physiological antagonism with one example
  204. Treatment of drug allergy
  205. Drug therapy in myocardial infarction
  206. Complications of General anaesthesia
  207. Therapeutic uses of prostaglandins
  208. --- Content provided by‌ FirstRanker.com ---

  209. Sodium valproate
  210. Aectazolamide
  211. Pre anaesthetic medication
  212. Management of status asthmaticus
  213. Therapeutic uses of cholinergic drugs
  214. --- Content provided by​ FirstRanker.com ---

  215. Osmotic diuretics
  216. Therapeutic uses of atropine and its substitutes
  217. Selective serotonin reuptake inhibitors
  218. Opioid receptors
  219. Ipratropium bromide
  220. --- Content provided by​ FirstRanker.com ---

  221. Ocular hypotensives
  222. Sumatriptan
  223. Treatment of acute gout
  224. Class antiarrhythmics
  225. Losartan
  226. --- Content provided by⁠ FirstRanker.com ---

  227. Bromocriptine
  228. COX-inhibitors
  229. Drug potency vs efficacy
  230. What is iatrogenic disease Give EXAMINATIONples
  231. Eutectic mixture
  232. --- Content provided by⁠ FirstRanker.com ---

  233. Cholinergic crisis
  234. Ebastine
  235. Treatment of acute paracetamol poisoning
  236. Ondansetron
  237. What are the antihypertensives to be avoided in pregnancy Give reasons
  238. --- Content provided by‌ FirstRanker.com ---

  239. Contraindications of heparin
  240. Uses of acetazolamide
  241. Cholinesterase reactivators in organophosphorus poisoning
  242. Heparin versus warfarin
  243. Role of glucocorticoids in bronchial asthma
  244. --- Content provided by‌ FirstRanker.com ---

  245. Drug therapy for chronic gout
  246. Mechanism of action of d-tubocurarine
  247. Drug therapy of Parkinsonism
  248. Mechanism of action and uses of antiplatelet drugs
  249. Pharmacotherapy of migraine
  250. --- Content provided by FirstRanker.com ---

  251. Mechanism of action of Phenytoin
  252. Atypical antipsychotics
  253. Salbutamol
  254. Dicyclomine
  255. Spironolactone
  256. --- Content provided by​ FirstRanker.com ---

  257. Nimesulide
  258. Name four antiarrythmics
  259. Name four peripherally acting skeletal muscle relaxants
  260. Ketorolac
  261. Four adverse effects of furosemide
  262. --- Content provided by FirstRanker.com ---

  263. Mention four uses of aspirin
  264. Mention four uses of furosemide
  265. Succinylcholine apnoease
  266. Types of synergism
  267. Uses of mast cell stabilizers
  268. --- Content provided by‍ FirstRanker.com ---

  269. Pharmacovigilance
  270. Bromhexine
  271. Nasal decongestants
  272. Sodium nitroprusside
  273. Therapeutic uses of alpha blockers
  274. --- Content provided by⁠ FirstRanker.com ---

  275. Mechanism of action of disulfiram
  276. Mechanism of action and therapeutic uses of digoxin
  277. Enumerate statins Write about mechanism of action and indications for statins
  278. Potassium sparing diuretics
  279. First pass metabolism with suitable example
  280. --- Content provided by​ FirstRanker.com ---

  281. Mechanism of action of tramadol
  282. Methanol poisoning
  283. Treatment of Glaucoma
  284. Write four therapeutic uses of prostaglandins
  285. Give two reasons for using morphine in left ventricular failure
  286. --- Content provided by⁠ FirstRanker.com ---

  287. Define plasma half life Give two examples of drugs with short half life
  288. Write two indications and two adverse effects of thiazides
  289. What is phase IV clinical trial?
  290. Mechanism of action, uses and adverse effects of sodium valproate
  291. Management of organophosphorus poisoning
  292. --- Content provided by FirstRanker.com ---

  293. Mechanism of action, uses and adverse effects of ketorolac
  294. Enumerate and discuss the role of inhaled steroids in bronchial asthma
  295. Pharmacogenetics
  296. Thiazide diuretics
  297. Adrenaline
  298. --- Content provided by‍ FirstRanker.com ---

  299. Inhalational corticosteroids
  300. Mention four antitussive drugs
  301. Name four anti-platelet drugs
  302. Mention four drugs used in migraine prophylaxis
  303. Serotonin syndrome
  304. --- Content provided by‌ FirstRanker.com ---

  305. Tachyphylaxis
  306. Name two merits and two demerits of rectal route of administration of drugs
  307. Rationale for using timolol in the treatment of glaucoma
  308. What is dissociative anaesthesia?
  309. Name two selective COX- inhibitors List two advantages in using selective COX- inhibitors
  310. --- Content provided by FirstRanker.com ---

  311. List the two uses of sodium cromoglycate
  312. Pre-anaesthetic medication
  313. Therapeutic uses of adrenergic drugs
  314. Mechanism of action and therapeutic uses of amlodipine
  315. Glycoprotein IIb/Illa receptor antagonist
  316. --- Content provided by‌ FirstRanker.com ---

  317. Mechanism of action and therapeutic uses of spironolactone
  318. Pharmacovigilance
  319. Plasma half life
  320. Alpha blockers
  321. Mast cell stabilizers
  322. --- Content provided by FirstRanker.com ---

  323. Spironolactone
  324. Tramadol
  325. Inhalational steroids in bronchial asthma
  326. Orphan drugs
  327. Name any two drugs used for glaucoma
  328. --- Content provided by‌ FirstRanker.com ---

  329. Mention the mechanism of action and two uses of allopurinol
  330. Mention any four uses of loop diuretics
  331. Write any four antitussives
  332. Write any one use and one adverse effect of abciximab
  333. Teratogenicity
  334. --- Content provided by​ FirstRanker.com ---

  335. Treatment of organophosphorous compound poisoning
  336. Drug therapy for moderate migraine
  337. Potassium channel openers
  338. Dopaminergic agonist in parkinsonism
  339. Ketamine
  340. --- Content provided by‍ FirstRanker.com ---

  341. Phase-III clinical trial
  342. State any one use and one adverse effect of labetalol
  343. Write any two uses and two adverse effects of aspirin
  344. Mention any four mucolytics
  345. Name any two drugs used for conscious sedation
  346. --- Content provided by⁠ FirstRanker.com ---

  347. Write any one use and one adverse effect of ranolazine
  348. What is zero order pharmacokinetics?
  349. Name two second generation anti-histamines and their therapeutic uses
  350. Name two therapeutic uses of cardiac glycosides
  351. List two advantages in using nitrous oxide for general anaesthesia
  352. --- Content provided by‍ FirstRanker.com ---

  353. Rationale of combining L-Dopa and Carbidopa in the treatment of Parkinsonism
  354. Parenteral route of drug administration
  355. Pharmacotherapy of status asthmaticus
  356. Parenteral iron therapy
  357. Discuss the advantages and therapeutic uses of low molecular weight heparin
  358. --- Content provided by‍ FirstRanker.com ---

  359. Therapeutic uses and side effects of furosemide
  360. Mention the mechanism of action, uses and adverse effects of NSAIDs
  361. Give examples of physical Antagonism
  362. Write the mechanism of action and major uses of Frusemide
  363. Enlist the advantages of Low Molecular Weight Heparin over conventional Heparin
  364. --- Content provided by‍ FirstRanker.com ---

  365. Enumerate Opioid Antagonists and their clinical uses
  366. Mention any Potassium channel openers and uses of these drugs
  367. Neprilysin Inhibitors
  368. Intracellular receptors
  369. Pressor agents
  370. --- Content provided by​ FirstRanker.com ---

  371. Mechanism of action, adverse effects and uses of Digoxin
  372. Role of Biologics in Rheumatoid Arthritis
  373. Inhalational Steroids
  374. Depolarising Neuromuscular blockers
  375. Mention adverse effects of theophylline
  376. --- Content provided by⁠ FirstRanker.com ---

  377. List four differences between buspirone and benzodiazepines
  378. Mention four common drug interactions in an alcoholic individual
  379. Adenosine
  380. Define bioavailability Why is it less when the drug is given orally?
  381. Discuss the mechanism of action, uses and techniques of local anaesthetics
  382. --- Content provided by​ FirstRanker.com ---

  383. Compare and contrast conventional and atypical antipsychotics
  384. Discuss the role of vasodilators in acute heart failure
  385. Discuss the mechanism of action, uses and adverse effects of spironolactone

--- Content provided by FirstRanker.com ---


This download link is referred from the post: MBBS 2nd Year (Second Year) Important Questions (Question Bank)