Download MBBS 2nd Year Pharmacology Paper II Important Questions

MBBS Second Year Pharmacology Paper-II Important
Question Bank

Essay Questions:
1. i) Enumerate the antimetabolites used in neoplastic diseases. ii) Write the mechanism of action

--- Content provided by FirstRanker.com ---

and therapeutic uses of Methotrexate. iii) Add a note on treatment of Methotrexate toxicity.
2. i) Classify antithyroid agents. ii) Mention the pharmacological actions and therapeutic uses of
carbimazole. iii) Add a note on radioactive iodine.
3. a) Classify dopamine receptors and mention its agonists and antagonists. b) Write mechanism of
action and pharmacological actions of metaclopramide. c) Therapeutic uses and adverse effects

--- Content provided by FirstRanker.com ---

of metaclopramide.
4. a) Classify anti tubercular drugs. b) Mechanism of action and bacterial spectrum of action of
rifampicin. c) Explain short course treatment of tuberculosis.
5. i) What are the various methods of hormonal contraception? ii) Discuss the mechanism of action
of hormonal contraceptives. iii) Mention the complications of contraceptive use.

--- Content provided by FirstRanker.com ---

6. i) Classify Antiamoebic drugs. ii) Discuss the adverse effects and indications of Nitroimidazoles
used in Amoebiasis. iii) Write briefly on Nitazoxanide.
7. i) Classify Glucocorticoids. ii) Mention Pharmacological actions of Glucocorticoids. iii) Enumerate
adverse effects and uses of Glucocorticoids.
8. i) Enumerate Anti Tubercular Drugs. ii) Write the Mechanism of Action and Adverse effects of

--- Content provided by FirstRanker.com ---

any one standard drug. iii) Write briefly on short course chemotherapy.
9. a. Classify the drugs used for the treatment of fungal infections. b. Explain the mechanism of
action, interactions, adverse effects and uses of Ketoconazole.
10. Discuss the pharmacotherapy of Helicobacter pylori infection.
11. Discuss the mechanism of action, Spectrum of activity and uses of Metronidazole.

--- Content provided by FirstRanker.com ---

12. a. Enumerate and discuss the pharmacology of newer insulin analogues. b. Add a note on insulin
resistance.
13. a. Classify fluroquinolones. b. Explain the mechanism of action and uses of second generation
fluroquinolones.
14. a. Classify Anti Thyroid drugs. b. Adverse effects and uses of propylthiouracil. c. Treatment of

--- Content provided by FirstRanker.com ---

thyroid storm.
15. Classify antimalarial drugs. Describe in detail about Chloroquine resistance Malaria treatment.
16. Classify immunosuppressants. Describe the mechanism of action, adverse effects and
therapeutic uses of calcineurin inhibitors.
17. a. Classify the drugs used for the treatment of peptic ulcer. b. Discuss the mechanism of action

--- Content provided by FirstRanker.com ---

and uses of proton pump inhibitors.
18. a. Classify the drugs used for Diabetes Mellitus. b. Discuss the actions and the available
preparations of insulin.

---

19. Classify Cephalosporins. Discuss the mechanism of action, uses and adverse effects of
Cephalosporins. Write briefly about postantibiotic effect.

--- Content provided by FirstRanker.com ---

20. Classify the drugs used for the treatment of fungal infections. Explain the mechanism of action,
drug interactions, adverse effects and therapeutic uses of Griseofulvin.
21. Classify the drugs used for tuberculosis. Discuss the mechanism of action, pharmacokinetics and
adverse effects of isoniazid.
22. a) Classify Beta lactam antibiotics. b) Mention the mechanism of action, adverse effects and uses

--- Content provided by FirstRanker.com ---

of Penicillins. c) Write briefly about Beta-lactamase inhibitors.
23. Classify drugs used in the treatment of malaria. Outline mechanism of action and advantages of
chloroquine. Write a note on prophylaxis of malaria.
24. Classify drugs used in peptic ulcer. Discuss the mechanism of action, uses and adverse effects of
proton pump inhibitors.

--- Content provided by FirstRanker.com ---

25. Classify anti emetic drugs. How will you manage? i) Motion sickness. ii) Morning sickness. iii)
Drug induced postoperative nausea and vomiting (PONV). iv) Anti cancer chemotherapy induced
vomiting.
26. Classify oral hypoglycemic drugs. Discuss the mechanism of action and adverse effects of
metformin. Why is it used as a first choice drug in type 2 diabetes mellitus patients?

--- Content provided by FirstRanker.com ---

27. Classify anti-tubercular drugs according to clinical utility. How will you treat? a) Newly diagnosed
pulmonary tuberculosis. b) Previously treated pulmonary tuberculosis. c) Multidrug resistant
(MDR) TB.
28. Classify beta lactam antibiotics. Enumerate the mechanism of action, adverse effects and
therapeutic uses of penicillins.

--- Content provided by FirstRanker.com ---

29. Classify antifungal drugs. Write in detail about mechanism of action, pharmacokinetics, clinical
uses and adverse effects of fluconazole.
30. A 35 year old male patient, known hyperthyroid is brought to emergency with c/o palpitation,
tremors and profuse sweating . O/E his pulse rate is 134/ min and BP is 160/100 mm/Hg.ECG
shows sinus tachycardia and a diagnosis of thyroid storm is made. a. How will you manage the

--- Content provided by FirstRanker.com ---

above condition. b. Discuss in detail the pharmacology of thioamides. c. Write briefly on
radioactive Iodine

--- Content provided by FirstRanker.com ---

---

Short Answer Questions:

1. Rationale for giving chloroquine and primaquine in acute vivax malaria
2. Rationale for using clofazimine in lepra reaction

--- Content provided by FirstRanker.com ---

3. Two Uses and Two adverse effects of metronidazole
4. Why ciprofloxacin is contraindicated in children less than yrs of age?
5. Two indications of albendazole
6. Sulfonylureas are not effective in Type I diabetes mellitus
7. What is grey baby syndrome?

--- Content provided by FirstRanker.com ---

8. Rationale for using Bromocriptine in acromegaly
9. Ranitidine is preferred to cimetidine in peptic ulcer
10. Cisplatin
11. INH
12. Management of cerebral malaria

--- Content provided by FirstRanker.com ---

13. Ketoconazole
14. Treatment of scabies
15. Management of diabetic ketoacidosis
16. Selective Estrogen Receptor Modulators (SERMS)
17. Newer insulin preparations

--- Content provided by FirstRanker.com ---

18. Low molecular weight heparins
19. Vitamin ? D
20. British Anti-Lewisite (BAL)
21. Proton pump inhibitors
22. Amikacin

--- Content provided by FirstRanker.com ---

23. Doxycycline
24. Bacterial resistance
25. Chloroquine
26. Carbimazole
27. Combined pill

--- Content provided by FirstRanker.com ---

28. Hormone replacement therapy
29. Fluconazole
30. Cyclosporin
31. DHF reductase inhibitors
32. Antianerboic antibiotics

--- Content provided by FirstRanker.com ---

33. Framycetin
34. Radio-active iodine

---

35. Oxytocin
36. GNRH analogues
37. Diloxanate furate

--- Content provided by FirstRanker.com ---

38. Bromocryptine
39. Vinca alkaloids
40. Folinic acid
41. Pyrazinamide
42. Drugs used in TYPHOID fever

--- Content provided by FirstRanker.com ---

43. Insulin resistance
44. Diethylcarbamazine citrate
45. Methotrexate
46. Prednisolone
47. Propylthiouracil

--- Content provided by FirstRanker.com ---

48. Ranitidine
49. Raloxifene
50. Pyrimethamine
51. Mention two calcineurin inhibitors Mention two uses
52. What is Cisplatin? Mention two uses

--- Content provided by FirstRanker.com ---

53. Name two conditions where multi drug therapy is indicated with antimicrobials
54. Mention two examples each for bacteriostatic and bactericidal drugs
55. What is the mechanism of action of Vinca alkaloids?
56. Which antithyroid drug inhibits hormone release from thyroid? Mention two uses
57. Mention two insulin analogues

--- Content provided by FirstRanker.com ---

58. Mention two Antioestrogens Mention two indications
59. Mention two conditions requiring Hormone replacement therapy What hormones
are given?
60. Name the Mast cell stabilizers What is their role in Bronchial asthma?
61. Adverse effects and uses of Metronidazole

--- Content provided by FirstRanker.com ---

62. Anticancer antibiotics
63. Clarithromycin
64. Insulin Resistance
65. Therapeutic uses of oxygen
66. Bisacodyl

--- Content provided by FirstRanker.com ---

67. Adverse effects of oral contraceptive pills
68. Ketoconazole
69. Iver mectin
70. Bacterial drug resistance

---

71. Mention two Injectable contraceptives

--- Content provided by FirstRanker.com ---

72. Mention two Betalactamase inhibitors and their uses
73. Name two drugs used in Anerobic Infections
74. Mention four Non malarial uses of chloroquine
75. Name two Topical & two systemic drugs used in Psoriasis
76. Write the mechanism of action and uses of Dimercaprol

--- Content provided by FirstRanker.com ---

77. Mention two differences between oxytocin and Ergometrine
78. Rationale in the use of Cotrimoxazole
79. Mention two Monoclonal antibodies and their uses
80. Justify the preference of Ranitidine over Cimetidine
81. Meropenem

--- Content provided by FirstRanker.com ---

82. Adverse effects and uses of lodides
83. Erythrocytic schizontocidal agents
84. Enumerate the serious complications of oral contraceptives
85. Indications for oral hypoglycemic agents
86. Management of functional constipation

--- Content provided by FirstRanker.com ---

87. Gentamicin ? PMMA (Polymethyl methacrylate) chain
88. Management of multi drug resistant Tuberculosis (MDR-TB)
89. Clofazimine in Leprosy
90. Fusion inhibitors in HIV infection
91. Mechanism of action of Cephalosporins

--- Content provided by FirstRanker.com ---

92. Post antibiotic effect
93. Cinacalcet
94. Name two highly selective corticosteroids and give their uses
95. Precautions for use of tetracyclines
96. Special pharmacokinetic properties of Azithromycin

--- Content provided by FirstRanker.com ---

97. Mechanism of action of Paclitaxe
98. Name four antiseborrheics
99. Ondansetron as an antiemetic
100.
Advantages of Artemisinin based Combination Therapy (ACT)

--- Content provided by FirstRanker.com ---

101.
Albendazole in Neurocysticercosis
102.
Oseltamivir
103.

--- Content provided by FirstRanker.com ---

Management of Lepra reaction
104.
Sulfasalazine as an antidiarrhoeal agent
105.
Atosiban

--- Content provided by FirstRanker.com ---

106.
Drugs used for Thyrotoxic crisis
107.
Chemoprophylaxis

---

108.

--- Content provided by FirstRanker.com ---

Ototoxicity produced by Aminoglycosides
109.
Vancomycin
110.
PUVA (Psoralen Ultra Violet A)

--- Content provided by FirstRanker.com ---

111.
Explain the mechanism of action & uses of Calcineurin inhibitors
112.
Bleomycin
113.

--- Content provided by FirstRanker.com ---

Tegaserod
114.
Pharmacotherapy of Gastro Esophageal Reflex Disease
115.
Zoledronate

--- Content provided by FirstRanker.com ---

116.
Emergency Contraception
117.
Gatifloxacin
118.

--- Content provided by FirstRanker.com ---

Name Superactive GnRH agonist & what are their uses
119.
Role of corticosteroids in Tuberculosis management
120.
Centrally acting muscle relaxants

--- Content provided by FirstRanker.com ---

121.
Complication of spinal anaesthesia
122.
Biological Response modifiers
123.

--- Content provided by FirstRanker.com ---

Therapeutic uses of Vitamin A
124.
Newer Macrolides
125.
Post Exposure prophylaxis of Rabies

--- Content provided by FirstRanker.com ---

126.
Dimercaprol
127.
Streptokinase
128.

--- Content provided by FirstRanker.com ---

Drugs for psoriasis
129.
Treatment of Bellodona poisoning
130.
Semi synthetic Penicillin

--- Content provided by FirstRanker.com ---

131.
Imipenem
132.
Name four Topical Anti fungals
133.

--- Content provided by FirstRanker.com ---

Injectable contraceptives
134.
Adverse effects of Aminoglycoside Antibiotics
135.
Oxytocin Antagonist

--- Content provided by FirstRanker.com ---

136.
Uses of Methotrexate
137.
Treatment of lepra reaction
138.

--- Content provided by FirstRanker.com ---

Enfuvirtide
139.
Intra vaginal preparations for Trchomonas Vaginalis
140.
Mechanism of action of ciprofloxacin

--- Content provided by FirstRanker.com ---

141.
Sulfone syndrome
142.
Enumerate the differences between propyl thiouracil and carbimazole
143.

--- Content provided by FirstRanker.com ---

Emergency contraception
144.
Citrovorum factor rescue

---

145.
Enumerate the contraindications of steroids

--- Content provided by FirstRanker.com ---

146.
Super ORS
147.
Mechanism of action of omeprazole
148.

--- Content provided by FirstRanker.com ---

Write the mechanism of action and uses of Ivermectin
149.
Newer formulations of Amphotericin B
150.
Prophylaxis of HIV infection

--- Content provided by FirstRanker.com ---

151.
Menopausal hormone replacement therapy
152.
Human insulins
153.

--- Content provided by FirstRanker.com ---

Sulfasalazine
154.
HT antagonists
155.
Antipseudomonal penicillins

--- Content provided by FirstRanker.com ---

156.
alpha reductase inhibitors
157.
Radioactive iodine
158.

--- Content provided by FirstRanker.com ---

Treatment of acne vulgaris
159.
Short course chemotherapy in tuberculosis
160.
Plasma expanders

--- Content provided by FirstRanker.com ---

161.
Drugs for Gastroesophageal reflux disease
162.
Rifampin
163.

--- Content provided by FirstRanker.com ---

Classification of anti cancer drugs
164.
Metformin
165.
Therapeutic uses and adverse effects of Gonadotropins

--- Content provided by FirstRanker.com ---

166.
Artemisinin based combination therapy
167.
Albendazole
168.

--- Content provided by FirstRanker.com ---

Sitagliptin
169.
Fourth generation cephalosporins
170.
Mention four anticoagulants used in vitro

--- Content provided by FirstRanker.com ---

171.
Mention four therapeutic uses of vitamin D
172.
Give four examples of Fluroquinolones
173.

--- Content provided by FirstRanker.com ---

Mention four antiretroviral drugs
174.
Mention four antimalarial drugs
175.
Mention four contraindication for heparin

--- Content provided by FirstRanker.com ---

176.
Mention four HMG-COA reductase inhibitors
177.
Mention four antiamoebic drugs
178.

--- Content provided by FirstRanker.com ---

Mention four first line Anti tubercular agents
179.
Mention four topical antifungal drugs
180.
Name four microtubule damaging agents used for chemotherapy for cancer

--- Content provided by FirstRanker.com ---

181.
Danazol

---

182.
Artemisinin derivatives in Malaria
183.

--- Content provided by FirstRanker.com ---

Ezetimibe
184.
Thrombolytic drugs
185.
Methotrexate

--- Content provided by FirstRanker.com ---

186.
Cotrimoxazole
187.
Clinical uses of Somatostatin and Octreotide
188.

--- Content provided by FirstRanker.com ---

Classify antiemetic agents
189.
Low molecular weight heparin
190.
British Anti lewisite

--- Content provided by FirstRanker.com ---

191.
Drug regimen in H Pylori
192.
Lepra reaction
193.

--- Content provided by FirstRanker.com ---

Why imipenem is administered with cilastatin?
194.
Mebendazole
195.
Adverse effects of Aminoglycosides

--- Content provided by FirstRanker.com ---

196.
Therapeutic uses of Metronidazole
197.
Mechanism of action of Sulfonylureas
198.

--- Content provided by FirstRanker.com ---

Hepatitis B vaccine
199.
Vitamin K
200.
Mechanism of action of Cotrimoxazole

--- Content provided by FirstRanker.com ---

201.
Mention four uses of corticosteroids
202.
Mention four factors affecting the absorption of iron
203.

--- Content provided by FirstRanker.com ---

Vinca alkaloids
204.
Oxytocin
205.
Bulk purgatives

--- Content provided by FirstRanker.com ---

206.
Prokinetic drugs
207.
Paclitaxel
208.

--- Content provided by FirstRanker.com ---

Domperidone
209.
Erythropoetin
210.
Statins

--- Content provided by FirstRanker.com ---

211.
Mention four drugs for Scabies
212.
Mention the toxicities of quinolones
213.

--- Content provided by FirstRanker.com ---

Mention four oral hypoglycemic drugs Mention their mechanisms of
action
214.
Mention four uses of thyroid hormone
215.

--- Content provided by FirstRanker.com ---

Antimotility drugs
216.
Two uses and two adverse effects of Vitamin D
217.
Mupirocin

--- Content provided by FirstRanker.com ---

---

218.
Write four immunosuppressant's and their uses
219.
Mention four newer oral anti-diabetic drugs
220.

--- Content provided by FirstRanker.com ---

Treatment of scabies
221.
Triple regimen for HPylori infection
222.
Advantages and contraindications of OCP

--- Content provided by FirstRanker.com ---

223.
Mechanism of action and therapeutic uses and adverse effects of lovastatin
224.
Mechanism of action, uses and adverse effects of methotrexate
225.

--- Content provided by FirstRanker.com ---

Enumerate insulin analogs Write their indications and advantages
226.
Mechanism of action, uses and adverse effects of metronidazole
227.
Bisphosphonates

--- Content provided by FirstRanker.com ---

228.
Mention four drugs used for acne
229.
Write two adverse effects and two contraindications of corticosteroids
230.

--- Content provided by FirstRanker.com ---

Write four general toxicities of cytotoxic drugs
231.
Write four adverse effects of oral contraceptive pills
232.
Two advantages and two disadvantages of radioactive iodine

--- Content provided by FirstRanker.com ---

233.
Mechanism of action and uses of antioxidants
234.
Mention the mechanism of action and adverse effects of Flouroquinolones
235.

--- Content provided by FirstRanker.com ---

Antibacterial spectrum of cefotaxime
236.
Mechanism of action and adverse effects of cyclophosphamide
237.
Topical therapy used in psoriasis

--- Content provided by FirstRanker.com ---

238.
Newer insulins
239.
Selective Estrogen Receptor Modulators (SERM)
240.

--- Content provided by FirstRanker.com ---

Discuss the mechanism of action, indications of desferrioxamine
241.
Drugs used in gastro esophageal reflux disease
242.
Discuss the principle and guidelines in the treatment of HIV

--- Content provided by FirstRanker.com ---

243.
Propylthiouracil
244.
Antimotility drugs
245.

--- Content provided by FirstRanker.com ---

Discuss the mechanism of action, and adverse effects of aminoglycosides
246.
Discuss the mechanism of action, uses and adverse effects of terbinafine
247.
Discuss in detail about pharmacokinetic drug interactions with suitable

--- Content provided by FirstRanker.com ---

examples
248.
Mention four therapeutic uses of octreotide
249.
Mention two anti-fibrinolytic drugs and two of their uses

--- Content provided by FirstRanker.com ---

250.
Mechanism of action and adverse effects of atorvastatin
251.
Anti-bacterial spectrum of azithromycin
252.

--- Content provided by FirstRanker.com ---

Mention four therapeutic uses of rifampicin
253.
Role of clofazimine in leprosy

---

254.
Mechanism of action and uses of finasteride

--- Content provided by FirstRanker.com ---

255.
Hepatitis B vaccine
256.
Discuss the status of oral hypoglycemic drugs in type diabetes mellitus
257.

--- Content provided by FirstRanker.com ---

Cyclosporine
258.
Highly active anti-retroviral therapy
259.
Mention the mechanism of action, uses and adverse effects of acyclovir

--- Content provided by FirstRanker.com ---

260.
Mechanism of action and adverse effects of metformin
261.
Mechanism of action and therapeutic uses of metoclopramide
262.

--- Content provided by FirstRanker.com ---

Nucleoside reverse transcriptase inhibitors in treatment of HIV
263.
Discuss alkylating agents used as anti-cancer drugs
264.
Radioactive iodine

--- Content provided by FirstRanker.com ---

265.
Short course chemotherapy in the treatment of tuberculosis
266.
Name two calcineurin inhibitors and list two uses of the calcineurin
inhibitors

--- Content provided by FirstRanker.com ---

267.
Name two new insulin delivery devices
268.
Two uses of penicillamine
269.

--- Content provided by FirstRanker.com ---

Name two drugs which are third generation cephalosporins
270.
Name two drugs used in the suppressive prophylaxis of malaria
271.
Name two adverse effects of aminoglycosides

--- Content provided by FirstRanker.com ---

272.
Clinical uses of desferrioxamine
273.
Name any four antiplatelet drugs
274.

--- Content provided by FirstRanker.com ---

Name any two bisphosphonates and mention any two of their uses
275.
Cyclosporine
276.
Name any four antiemetics

--- Content provided by FirstRanker.com ---

277.
Anti-pseudomonal penicillins
278.
Deflazacort
279.

--- Content provided by FirstRanker.com ---

Directly observed shortcourse treatment for TB
280.
Mechanism of action, adverse events and therapeutic uses of erythromycin
281.
Prostaglandin analogues used in treatment of peptic ulcer

--- Content provided by FirstRanker.com ---

282.
Treatment of psoriasis
283.
Injectable contraceptives
284.

--- Content provided by FirstRanker.com ---

Proteasome inhibitors
285.
Third generation Cephalosporins
286.
Drugs acting on glucagon like peptide receptors

--- Content provided by FirstRanker.com ---

287.
Mycophenolatemofetil
288.
Chemoprophylaxis of Tuberculosis
289.

--- Content provided by FirstRanker.com ---

Mention uses and advance effects of Methyl Prednisolone

---

290.
Write any regimens for prophylaxis of surgical site infection
291.
What is Teicoplanin? Write its mechanism of action and uses

--- Content provided by FirstRanker.com ---

292.
Write any drug interactions of Pyridoxine
293.
Write two mechanism of action and uses of Paclitaxel
294.

--- Content provided by FirstRanker.com ---

Treatment of acute Amoebic dysentery

***************************************

---