Download OU (Osmania University) M.Pharma-Ph.Chemistry (Master of Pharmacy) 1st Sem 2018 1295PCI Chemistry Of Natural Products Previous Question Paper
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Code No. 1295/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutical Chemistry) I-Semester (PCI) (Supple.) Examination,
August 2018
Subject: Chemistry of Natural Products
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Discuss the structural elucidation of morphine (OR) reserpine. (15)
2 Discuss how natural products acted as leads while designing the drugs?
Explain by taking any three categories of drugs.
3 (a) What are flavanoids? Discuss the structural elucidation of quercetin.
(b) Discuss the chemistry and mechanism of contraceptive steroids. (7+8)
4 What are isoprene and special isoprene rules? Discuss the structural elucidation
of any one monoterpeniod and one diderpenoid. (15)
5 Write the approximate spectral values for the following natural drugs in IR,
1
HNMR and
13
CNMR spectra. (5x3)
(a) Morphine
(b) Any one Digitalis glycoside
(c) Benzyl penicillin
(d) Quercetin
(e) Vitamin ? D
6 Write a note on : (3x5)
(a) Recombinant DNA technology and drug discovery
(b) Chemistry of Vitamin A
(c) Stereochemistry and nomenclature of steroids
7 (a) Explain how natural products acted as leads in the discovery of newb -lactam
antibiotics and macrolide antibiotics.
(b) Discuss the structural elucidation of Ephedrine. (7+8)
8 (a) List t the active constituents that are isolated from the following crude
drugs with their medicinal use
(i) Pterocarpus marsupiam
(ii) Swertia chirata
(iii) Phyllanthus niruri
(iv) Curcuma longa Linn (8)
(b)Write a note on Gene therapy. (7)
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This post was last modified on 19 July 2020