Download OU M.Pharma Ph.Chemistry 2nd Sem 2020 6116PCI Pharmaceutical Process Chemistry Question Paper

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Code No. 6116/PCI

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FACULTY OF PHARMACY

M. Pharmacy (Pharm. Chemistry) II-Semester (PCI) (Suppl.) Examination, January 2020

Subject: Pharmaceutical Process Chemistry

Time: 3 Hrs Max. Marks: 75

Note: Answer any five questions. All questions carry equal marks.

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1. (a) Explain in detail validation of Large scale process. (7)
   (b) Write the types and sources of impurities in API. (8)
2. (a) Write a note on types of extraction. (8)
   (b) Discuss the factors affecting the evaporation. (7)
3. (a) Write the kinetics and mechanism of aromatic nitration. (8)
   

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   (b) Write a note on types of oxidation reaction and oxidizing agents. (7)
4. (a) Explain the production of statins. (7)
   (b) Discuss the case study on Industrial reduction process. (8)
5. (a) Write a detail note on MSDS. (8)
   (b) Discuss abt effluents and management system in industries. (7)

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6. (a) Explain the kinetics of halogenations reaction. (6)
   (b) Write abt hazards labels of chemicals and personal protection equipment. (9)
7. (a) Discuss abt cost effective routes, reagents selection and families to reagents useful for scale-up. (8)
   (b) Explain hydrogen transfer reactions in reduction. (7)
8. (a) Write the importance of OHSAS. (8)
   

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   (b) Explain the production of ‘streptomycin by fermentation. (7)

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