Download OU (Osmania University) M.Pharma-Ph.Chemistry (Master of Pharmacy) 2nd Semester 2019 13167PCI Advanced Spectral Analysis Previous Question Paper
- -
Code No. 13167/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutical Chemistry) II-Semester (PCI) (Suppl.) Examination,
February 2019
Subject : Advanced Spectral Analysis
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 a) Write down the wood ward ? Fieser rules for 1,3-butadienes and ? ? , -Carbonyl
Compnds. Calculate the ? max for the following.
b) How do y know the presence of C ? N, NH
2
, OH, SO
2
and NO
2
grps in IR?
(Indicate the wave number ranges). (10+5)
2 Discuss abt any two 2 -D NMR techniques in interpretation of structure of organic
compnds.
3. a) Discuss the fragmentation patterns of following functional grps in mas s
Spectrometry
a) Alkanes b) Carbonyl compnds c) Amines d) Alcohols.
b) Explain Mc Lafferty rearrangement.
c) How do y defect the isotopic peaks in mass spectrometry? (8+4+3)
4. Discuss the principle, instrumentation and applications of any two of the following:
a) GC-MS b) HPTLC c) Flash chromatography
5. Discuss the principle, instrumentation and applications of
a) DSC b) Raman Spectroscopy
6. a) Explain the principle and applications of ELISA
b) Discuss radio immune assay of insulin (8+7)
7. Write a note on the following (any two)
a) Super Critical fluid chromatography
b) LC-MS
c) Ion-exclusion chromatography
8. a) Draw a rgh ?HNMR Sp ectra for the following with proton splitting pattern
b) Where shall we expect the C=O strechings for the following aromatic compnds?
a) Aldehydes b) Ketones c) Carboxylic acids d) esters
e) ? ?lactams f) amides g) anhydrides
h) ? ? , ? Unsaturated carbonyl compnds (8)
*******
FirstRanker.com - FirstRanker's Choice
- -
Code No. 13167/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutical Chemistry) II-Semester (PCI) (Suppl.) Examination,
February 2019
Subject : Advanced Spectral Analysis
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 a) Write down the wood ward ? Fieser rules for 1,3-butadienes and ? ? , -Carbonyl
Compnds. Calculate the ? max for the following.
b) How do y know the presence of C ? N, NH
2
, OH, SO
2
and NO
2
grps in IR?
(Indicate the wave number ranges). (10+5)
2 Discuss abt any two 2 -D NMR techniques in interpretation of structure of organic
compnds.
3. a) Discuss the fragmentation patterns of following functional grps in mas s
Spectrometry
a) Alkanes b) Carbonyl compnds c) Amines d) Alcohols.
b) Explain Mc Lafferty rearrangement.
c) How do y defect the isotopic peaks in mass spectrometry? (8+4+3)
4. Discuss the principle, instrumentation and applications of any two of the following:
a) GC-MS b) HPTLC c) Flash chromatography
5. Discuss the principle, instrumentation and applications of
a) DSC b) Raman Spectroscopy
6. a) Explain the principle and applications of ELISA
b) Discuss radio immune assay of insulin (8+7)
7. Write a note on the following (any two)
a) Super Critical fluid chromatography
b) LC-MS
c) Ion-exclusion chromatography
8. a) Draw a rgh ?HNMR Sp ectra for the following with proton splitting pattern
b) Where shall we expect the C=O strechings for the following aromatic compnds?
a) Aldehydes b) Ketones c) Carboxylic acids d) esters
e) ? ?lactams f) amides g) anhydrides
h) ? ? , ? Unsaturated carbonyl compnds (8)
*******
- -
Code No. 1221/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharm. Chemistry) II-Semester (PCI) (Main) Examination,
August 2018
Subject : Advanced Spectral Analysis
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 a) Discuss any two 2DNMR (NOESY, COSY, HETCOR) techniques of and explain
their importance in structural interpretation of organic compnds.
2 a) Write the wood ward ? Fieser rules for ? ? , -Carbonyl Compnds and 1, 3 ?
butadiene?s. Calculate ? max for the following compnds.
b) Explain the importance of meta stable ion peaks and isotopic peaks in mass
spectroscopy. (9+6)
3 Discuss the principle, instrumentation and applications of any two of the following
a) LC-MS b) HPTLC c) Super Critical fluid Chromotography.
4 Explain principle instrumentation and applications of any two of the following
techniques
a) DSC b) TGA c) Raman Spectroscopy (3x5)
5 a) Discuss the fragmentation of important functional grps in mass spectroscopy.
b) Explain MC Lafferty rearrangement and ring rule (10+5)
6 a) Explain the principle and applications of any two of the following instrumentation
techniques:
a) Flash chromcotography
b) LC-FTIR
c) Ion exclusion chromatography
7 Write a note on any two of the following
a) ELISA and its applications
b) Radioiumuno assay of insulin
c) Bioassays
..2
FirstRanker.com - FirstRanker's Choice
- -
Code No. 13167/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutical Chemistry) II-Semester (PCI) (Suppl.) Examination,
February 2019
Subject : Advanced Spectral Analysis
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 a) Write down the wood ward ? Fieser rules for 1,3-butadienes and ? ? , -Carbonyl
Compnds. Calculate the ? max for the following.
b) How do y know the presence of C ? N, NH
2
, OH, SO
2
and NO
2
grps in IR?
(Indicate the wave number ranges). (10+5)
2 Discuss abt any two 2 -D NMR techniques in interpretation of structure of organic
compnds.
3. a) Discuss the fragmentation patterns of following functional grps in mas s
Spectrometry
a) Alkanes b) Carbonyl compnds c) Amines d) Alcohols.
b) Explain Mc Lafferty rearrangement.
c) How do y defect the isotopic peaks in mass spectrometry? (8+4+3)
4. Discuss the principle, instrumentation and applications of any two of the following:
a) GC-MS b) HPTLC c) Flash chromatography
5. Discuss the principle, instrumentation and applications of
a) DSC b) Raman Spectroscopy
6. a) Explain the principle and applications of ELISA
b) Discuss radio immune assay of insulin (8+7)
7. Write a note on the following (any two)
a) Super Critical fluid chromatography
b) LC-MS
c) Ion-exclusion chromatography
8. a) Draw a rgh ?HNMR Sp ectra for the following with proton splitting pattern
b) Where shall we expect the C=O strechings for the following aromatic compnds?
a) Aldehydes b) Ketones c) Carboxylic acids d) esters
e) ? ?lactams f) amides g) anhydrides
h) ? ? , ? Unsaturated carbonyl compnds (8)
*******
- -
Code No. 1221/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharm. Chemistry) II-Semester (PCI) (Main) Examination,
August 2018
Subject : Advanced Spectral Analysis
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 a) Discuss any two 2DNMR (NOESY, COSY, HETCOR) techniques of and explain
their importance in structural interpretation of organic compnds.
2 a) Write the wood ward ? Fieser rules for ? ? , -Carbonyl Compnds and 1, 3 ?
butadiene?s. Calculate ? max for the following compnds.
b) Explain the importance of meta stable ion peaks and isotopic peaks in mass
spectroscopy. (9+6)
3 Discuss the principle, instrumentation and applications of any two of the following
a) LC-MS b) HPTLC c) Super Critical fluid Chromotography.
4 Explain principle instrumentation and applications of any two of the following
techniques
a) DSC b) TGA c) Raman Spectroscopy (3x5)
5 a) Discuss the fragmentation of important functional grps in mass spectroscopy.
b) Explain MC Lafferty rearrangement and ring rule (10+5)
6 a) Explain the principle and applications of any two of the following instrumentation
techniques:
a) Flash chromcotography
b) LC-FTIR
c) Ion exclusion chromatography
7 Write a note on any two of the following
a) ELISA and its applications
b) Radioiumuno assay of insulin
c) Bioassays
..2
- -
Code No. 1221/PCI
-2-
8. a) Draw a rgh ?HNMR Spectra for the following compnds with proton splitting
b) How do y interp ret the following functional grps in IR? (any six)
i) NO
2
ii) SO
2
iii) NH
2
iV) R -
O
II
C - OR V) CONH
Vi) COOH Vii) CN Viii) CHO ix) -
O
II
C - V) OH (9+6)
*******
Code No. 1221/PCI
-2-
8. a) Draw a rgh ?HNMR Spectra for the following compnds with proton splitting
b) How do y interp ret the following functional grps in IR? (any six)
i) NO
2
ii) SO
2
iii) NH
2
iV) R -
O
II
C - OR V) CONH
Vi) COOH Vii) CN Viii) CHO ix) -
O
II
C - V) OH (9+6)
*******
Code No. 1221/PCI
-2-
8. a) Draw a rgh ?HNMR Spectra for the following compnds with proton splitting
b) How do y interp ret the following functional grps in IR? (any six)
i) NO
2
ii) SO
2
iii) NH
2
iV) R -
O
II
C - OR V) CONH
Vi) COOH Vii) CN Viii) CHO ix) -
O
II
C - V) OH (9+6)
*******
FirstRanker.com - FirstRanker's Choice
This post was last modified on 19 July 2020