OU M.Pharm Question Papers Last 10 Years 2010-2020 || Osmania University
Code. No: 6106/PCI
FACULTY OF PHARMACY
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M. Pharmacy (Pharmaceutics) II-Semester (PCI) (Suppl.) Examination, January 2020
Subject: Molecular Pharmaceutics (Nano Technology and Targeted Drug Delivery Systems)
Time: 3 Hrs Max. Marks: 75
Note: Answer any Five Questions. All Questions Carry Equal Marks.
- (a) Define drug targeting? What are the ideal characteristics of a carrier? 6
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(b) Explain different types of drug targeting in detail? 9 - Explain different types of tumor targeting methods in detail? 15
- (a) Explain various transport mechanisms across Blood brain barrier? 5
(b) Describe in detail invasive and non-invasive brain targeting methods? 10 - (a) Describe hybridoma technology of Mab preparation? 8
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(b) How will you characterize monoclonal antibodies? 7 - (a) What are liposomes? Explain the role of cholesterol in the preparation of liposomes? 5
(b) Explain any five (5) methods of preparation of liposomes? Add a note on fate of liposomes? 10 - What are aquasomes? Describe in detail method of preparation and characterization of aquasomes? 15
- (a) What are aerosols? Explain various propellants used in the manufacturing of aerosols 7
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(b) Describe in detail evaluation methods of nasal drug delivery system? 8 - (a) What are gene drug delivery systems? Explain in detail viral and non viral gene transfer methods? 9
(b) Write a note on liposomal gene drug delivery system? 6
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