Download OU M.Pharma Pharmacology 2nd Sem 2019 13173PCI Principles Of Drug Discovery Question Paper

Download OU (Osmania University) M.Pharma-Pharmacology (Master of Pharmacy) 2nd Semester 2019 13173PCI Principles Of Drug Discovery Previous Question Paper

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Code No: 13173/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmacology) II-Semester (PCI) (Suppl.) Examination,
February 2019
Subject: Principles of Drug Discovery
Time: 3 Hrs Max. Marks : 75
Note: Answer any five questions. All questions carry equal marks.
1. a) Write a note on economics of drug discovery. 7
b) Describe abt role of zinc finger proteins in target identification and validation. 8
2. a) Write a note on combinatorial chemistry. 8
b) Explain in brief abt reporter gene assay. 7
3. a) Write a note on drug likeness screening. 5
b) Explain in detail abt rational drug design. 10
4. a) Write a note on rigid docking. 5
b) Describe in brief abt QSAR. 10
5. a) Write the significance of Prodrug design. 5
b) Describe abt the COMFA and COMSIA. 10
6. a) Explain in brief abt role of bioinf ormatics in drug discovery. 6
b) Describe the computational prediction of structure. 9
7. a) Write a note on scintillation proximity assay. 6
b) Describe the concept of pharmacophore based screening. 9
8. a) Write a note on statistical methods in QSAR. 8
b) Describe in brief abt rational of Prodrug design. 7
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