UNIVERSITY OF JAEENARSRI.JMANKA
SECOND EXAMINATION FOR MEDICAL DEGREES—PART II (2nd) December 2012
PHARMACOLOGY - Paper II
Date: 13.12.2012. Time: 02 hours
ANSWER ALL THE FOUR QUESTIONS
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Explain the pharmacokinetic basis for
- unexpected pregnancy in women on combined oral contraceptive pills following the use of broad spectrum antibiotics. (40 Marks)
- using probenacid in the treatment of chronic gout. (30 Marks)
- reduced efficacy of clopidogrel when taken with omeprazole. (30 Marks)
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- Classify the drugs used in the treatment of bronchial asthma. (20 Marks)
- Describe the mechanism of action of each group of drugs mentioned in 2.1. (40 Marks)
- Mention the different preparations available for each drug used in the treatment of bronchial asthma. (40 Marks)
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Write an account on
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- therapeutic applications of carbamazepine. (30 Marks)
- adverse effects of methotrexate. (30 Marks)
- drug interactions of warfarin. (40 Marks)
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Twenty year old girl with diabetes was admitted to the emergency unit in confused state. On examination respiratory rate was 35/ minute and she was dehydrated. Mother said that her daughter had stopped taking the medicine for diabetes for some time. The patient was treated for diabetic ketoacidosis.
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- List the therapeutic agents that you would use in the immediate management of this patient. (20 Marks)
- Explain the rationale for using the therapeutic agents mentioned in 2.1. for this patient. (40 Marks)
- Name the drug that you would prescribe for this patient on discharge. (10 Marks)
- Write the advice that you would give to this patient on discharge. (30 Marks)
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