UNIVERSITY OF JAFFNA, SRI LANKA
SECOND EXAMINATION FOR MEDICAL DEGREES (PART 1) February 2012
MICROBIOLOGY — Paper II
Date: 21.02.2012
Time: 2 hours
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9.00 - 11.00am
ANSWER ALL FOUR QUESTIONS
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A 35 year old man presented to the Jaffna Teaching Hospital with fever & headache of 3 days duration. On clinical examination, he was found to have splenomegaly and an eschar on the perineal region.
- What is the most likely diagnosis? (IOMarks)
- State the etiological agent of this disease (IOMarks)
- Describe the pathogenesis of this disease (35Marks)
- List the laboratory investigations to diagnose this disease. (15Marks)
- Mention the treatment of this disease (IOMarks)
- Describe briefly the prevention of this disease (20Marks)
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Explain the pathogenesis of the following infective diseases:
- Gas gangrene (35Marks)
- Tuberculosis (35Marks)
- Dengue haemorrhagic fever (DHF) (30Marks)
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A 40 year old man presented to the STD clinic with urethral discharge
- List the possible causative agents (10 Marks)
- Explain the laboratory tests for confirmation of each of the microorganism mentioned in 3.1 (30 Marks)
- Name the drug of choice and alternative drug for each of the organism mentioned in 3.1 (25 Marks)
- Describe the mode of transmission and preventive measures of AIDS (35Marks)
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- "Blood culture is better than the SAT for the diagnosis of Typhoid fever" Discuss the above statement (30Marks)
- Briefly compare and contrast the Hepatitis A & B viruses in relation to morphology and transmission (20Marks)
- Write notes on the following
- Cryptococcosis (20 Marks)
- Delayed hypersensitive reaction (30 Marks)
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