UNIVERSITY OF JAFFNA, SRI LANKA
SECOND EXAMINATION FOR MEDICAL DEGREES PART II (SECOND)
JANUARY 2012
Pharmacology - Paper II
Date: 02.02.2012.
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Time: 02 hours
ANSWER ALL THE FOUR QUESTIONS
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Explain the pharmacological basis for
- using morphine in the immediate management of myocardial infarction. (40 Marks)
- combining levodopa and carbidopa. (30 Marks)
- preferring low molecular heparins for the prophylaxis of thromboembolism over unfractionated heparin. (30 Marks)
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- List the first-line antituberculous drugs. (20 Marks)
- Briefly describe the mechanism of action of each of the drug mentioned above. (40 Marks)
- Mention the important adverse effects of the drugs mentioned in 2.1. (20 Marks)
- Outline the precautions you would take to prevent/ minimise the adverse effects mentioned above. (20 Marks)
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Write an account on the therapeutic applications of
- aspirin. (30 Marks)
- benzodiazepines. (30 Marks)
- glucocorticoids. (40 Marks)
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A 18 year old girl collapsed at the outpatient department after receiving benzathine penicillin injection for rheumatic fever prophylaxis. Her blood pressure was 80/60 mmHg and respiratory system examination revealed stridor and wheeze. She was treated for anaphylactic shock.
- Explain the basis for the signs and symptoms of this patient. (30 Marks)
- List the drugs that are used to treat this patient. (20 Marks)
- Explain the rationale for using the drugs mentioned in 4.2. to treat this patient. (40 Marks)
- Mention the alternative drugs that could be used for rheumatic fever prophylaxis for this patient. (10 Marks)
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