Download University of Jaffna MBBS 2012 January Pharmacology Paper II Question Paper

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ANSWER ALL THE FOUR QUESTIONS

1. Explain the pharmacological basis for

   1. using morphine in the immediate management of myocardial infarction. (40 Marks)
   2. combining levodopa and carbidopa. (30 Marks)

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   3. preferring low molecular heparins for the prophylaxis of thromboembolism over unfractionated heparin. (30 Marks)
2. 1. List the first-line antituberculous drugs. (20 Marks)
   2. Briefly describe the mechanism of action of each of the drug mentioned above. (40 Marks)
   3. Mention the important adverse effects of the drugs mentioned in 2.1. (20 Marks)

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   4. Outline the precautions you would take to prevent/ minimise the adverse effects mentioned above. (20 Marks)

3. Write an account on the therapeutic applications of

   1. aspirin. (30 Marks)
   2. benzodiazepines. (30 Marks)

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   3. glucocorticoids. (40 Marks)

4. A 18 year old girl collapsed at the outpatient department after receiving benzathine penicillin injection for rheumatic fever prophylaxis. Her blood pressure was 80/60 mmHg and respiratory system examination revealed stridor and wheeze. She was treated for anaphylactic shock.

   1. Explain the basis for the signs and symptoms of this patient. (30 Marks)
   2. List the drugs that are used to treat this patient. (20 Marks)

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   3. Explain the rationale for using the drugs mentioned in 4.2. to treat this patient. (40 Marks)
   4. Mention the alternative drugs that could be used for rheumatic fever prophylaxis for this patient. (10 Marks)

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