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Download University of Jaffna MBBS 2013 August Pharmacology Paper II Question Paper

Download University of Jaffna (University of Sri Lanka) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2013 August Pharmacology Paper II Previous Question Paper

This post was last modified on 19 October 2021

UNIVERSITY OF JAFFNA, SRI LANKA

SECOND EXAMINATION FOR MEDICAL DEGREES PART II (1s')

August 2013

PHARMACOLOGY - Paper II

Date: 29.08.2013

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Time: 02 hours

ANSWER ALL THE FOUR QUESTIONS.

Answer each Question in separate answer book.

  1. Explain the pharmacological basis for using

    • 1.1. benzathinepenicillin in prophylaxis of rheumatic fever. (25 marks)
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    • 1.2. high dose atorvastatin in the immediate treatment of myocardial (25 marks) infarction.
    • 1.3. misoprostol to prevent NSAIDs-induced peptic ulcer disease. (25marks)
    • 1.4. sodium cromoglycate in the management of exercise induced asthma. (25marks)
    • 2.1. Describe the pharmacokinetics of
      • 2.1.1. carbamazepine. (20 marks)
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      • 2.1.2. sodium valproate. (20 marks)
    • 2.2. Explain briefly the pharmacodynamics of
      • 2.2.1. carbamazepine. (10 marks)
      • 2.2.2. sodium valproate. (10 marks)
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    • 2.3. List two (02) clinically important adverse drug reactions of
      • 2.3.1. carbamazepine. (10 marks)
      • 2.3.2. sodium valproate. (10 marks)
    • 2.4. Discuss the term "risk versus benefit assessment" in the context of (20 marks) antiepileptic drug treatment.
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    • 3.1. Classify insulins based on the duration of action with example. (30 marks)
    • 3.2. Describe the insulin regimens used in the treatment of type 1 diabetes mellitus. (45 marks)
    • 3.3. Write the advice that you would give to the patients when prescribing (25 marks) insulin.
  3. Mrs. Ranjani was a 25 year old housewife. She underwent cardiac valve replacement 2 years ago and her cardiac functions were stable. She was on warfarin 10mg daily. Mrs. Ranjani wanted to have a baby.

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    • 4.1. Describe the anticoagulant therapy that you would plan for her during (30 marks) pregnancy.
    • 4.2. Explain the rationale for preferring the anticoagulant mentioned in 4.1. for this patient. (30 marks)
    • 4.3. Describe the precautions that have to be taken when using the drugs mentioned in 4.1. (40 marks)

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