Download University of Jaffna (University of Sri Lanka) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2019 February Microbiology Paper II Previous Question Paper
UNIVERSITY OF JAFFNA, SRI LANKA
ECOND EXAMINATION FOR MEDICAL DEGREES (2 nd )
February 2019
Microbiology Paper II
Date: 12. 02. 2019
Time allowed: 2 hours
Answer all four questions.
1 A 43-year-old lady was admitted to the Teaching Hospital, Jaffna with a history of high grade
fever for 6 days, headache and body aches. There were no rashes or jaundice noted on
examination but a painless esehar was noted in the axilla. After empirical treatment with
doxycycline, her fever dropped within 48 hours.
1.1
What is the most likely clinical diagnosis`?
(10 marks)
1.2
Mention the causative agent responsible for the clinical diagnosis given
by you in 1 .1
(10 marks)
.
1.3
Describe briefly the source and mode of transmission of the aetiological
agent given by you in 1.1.
(15 marks)
1.4
Describe the pathogenesis of the disease given by you in 1.1.
(20 marks)
1.5
Discuss the microbiological tests to confirm the diagiosis in this patient.
(25 marks)
1.6
Describe briefly the prevention of the disease given by you in 1.1.
(20 marks)
2
2.1
A 52- year-old fanner presented to the dermatology clinic with yellowish white discolouration
of distal and lateral ends ofnails of all fingers of both hands for the last five months. The
patient was treated with an antifungal agent_
2.1.1 What is the most likely clinical diagnosis for the above presentation?
(10 marks)
2.1.2 Name three fungal genera that might be responsible for the above lesion.
(15 marks)
2.1.3 What are the likely predisposing causes for this infection?
(15 marks)
2.1.4 Discuss the antifungal agents used in this patient.
(10 marks)
2.2
An `atopic' boy developed itchy red eyes, sneezing and a runny nose each time after playing in
the garden.
2.2.1 State the condition he has developed.
(05 marks)
2.2.2 Name the type of hypersensitivity reaction responsible for the above
(10 marks)
condition.
2,2.3 Describe the pathogenesis of the hypersensitivity reaction he has got.
(35 marks)
3
A 58 year old woman, presented with a history of fever associated with chills and rigors of three
days duration. She also complained of suprapubic pain and pain during rnicturition. On
examination she was febrile, and there was suprapubic tenderness but no loin tenderness.
3.1
What is the most probable diagnosis in this patient?
(10 marks)
3.2
List five common aetiological agents for this condition.
(10 marks)
3.3
Discuss the possible risk factors for the condition in this patient.
(25 marks)
3.4
Briefly describe how you would arrive at the microbiological diagnosis
(30 marks)
in this patient.
3.5
Discuss the principles of choosing empirical antibiotic therapy in this
(25 marks)
patient.
4
A 32 year old man is admitted to the medical ward with a history of nausea and loss of
appetite for two weeks. He had returned from Taiwan after a business trip one month
back. He does not have jaundice. The abdominal examination reveals hepatomegaly. His
physician wants to exclude hepatitis B infection.
4.1
Describe briefly the likely sources and modes of transmission of
hepatitis B virus in this patient.
(25 marks)
4.2
Describe briefly the sequelae of hepatitis B infection.
(20 marks)
4.3
State all the diagnostic viral markers of Hepatitis B infection and briefly (30 marks)
describe the clinical role of each.
4.4
Describe how this patient could have been prevented from Hepatitis B
(25 marks)
infection,
This post was last modified on 19 October 2021