Download University of Jaffna MBBS 2021 January Microbiology Paper II Question Paper

Download University of Jaffna (University of Sri Lanka) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2021 January Microbiology Paper II Previous Question Paper

UNIVERSITY OF JAFFNA, SRI LANKA
SECOND EXAMINATION FOR MEDICAL DEGREES PART I (1st)
JANUARY 2021
Microbiology Paper II
Date: 05.01.2021.
Time allowed: 2 hours
Answer all four questions.
Answer each question in a separate answer book.
1.
A 45-year-old patient developed rapidly spreading pain and swelling of the lower
limb following a prick injury. On examination, severe edema of the lower limb was
noted with erythema, blistering and bullae formation. Gas gangrene was clinically
suspected.
1.1
State the most likely anaerobic bacteria contributing to this
presentation.
(10 marks)
1.2
Describe the pathogenesis of this condition.
(60 marks)
1.3
State three principles in managing this patient.
(30 marks)
2.
A 28-year-old man presented to the dermatology clinic with an itchy rash in the
On examination, the rash was found to be an annular, scaly lesion with a slightly
elevated reddish edge and sharp border. The dermatologist started empirical
treatment with antifungal drugs.
2.1
What is the most likely clinical diagnosis for the above stated
condition?
(10 marks)
2.2
Name three fungal genera that might be responsible for the above
lesion.
(15 marks)
2.3
Name two other sites where the same fungal genera may cause
infection.
(10 marks)
2.4
Describe the specimen collection from all three sites and
transport to identify the fungal aetiology in this patient.
(40 marks)
2.5
Describe the antifungal agents used to treat the infections in all
three sites.
(25 marks)

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3. A 36-year-old man was diagnosed as infected with HIV.
3.1
Describe the possible sour' ces, modes of transmission and
risk factors for this infection in this man.
(30 marks)
3.2
Describe briefly the pathogenesis of HIV infection and
its possible consequences in this man.
(20 marks)
3.3
Describe the tests used for screening, confirmation
and monitoring the progress of HIV infection.
(20 marks)
3.4
A nursing officer accidentally got a needle stick injury
while collecting blood from this patient. Describe the post
exposure management for this nursing officer.
(30 marks)
4. 4.1 Explain the term 'sepsis.'
(10 marks)

4.2 Briefly describe the pathogenesis of sepsis.
(40 marks)

4.3 State the bedside clinical criteria of sepsis (gSOFA) and indicate how
organ dysfunction is recognized using the qS0FA score.
(20 marks)
4.4.1 Name 5 likely source of sepsis in a 70 year old ventilated patient
in the Intensive Care Unit (ICU).
(15 marks)
4.4.2 State what samples you would send the microbiology laboratory

from this patient to identify the bacterial cause of sepsis.
(15 marks)

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