Download MBBS 2nd Year WBUHS MBBS Microbiology Paper I 2023 March April Question Paper

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The West Bengal University of Health Sciences

MBBS 2nd Professional Examination (New Regulation) March - April 2023

Subject: Microbiology

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Paper: 1

Attempt all questions. The figures in the margin indicate full marks.

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Full Marks: 100 Time: 3 hours

1. a) A 9 year old girl is admitted in the pediatric ward with history of fever not touching the baseline and is increasing gradually over the past 6 days. She was having pain in abdomen, loss of appetite and general weakness. On examination, she was found to have a temperature of 101°F, pallor, coated tongue, mild splenomegaly and abdominal tenderness.
   1. What is the clinical condition?
   2. What are the likely bacterial agents involved?
   3. How will you establish the etiological diagnosis in the laboratory?

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   4. Outline the treatment guideline in this case.
   5. Can you prevent such infection? 1+2+8+2+2
   b) A male patient from Bihar attended OPD with fever, anemia and huge enlarged spleen for last 6 months. He is also having blackish discoloration of the skin.
   1. What is the most probable diagnosis and what is the vector?
   2. Which protozoa is responsible for this?
   3. Describe the immunopathogenesis of the disease. 2-2-6+5

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   4. How will you diagnose the case in the laboratory?
   
   


2. a)
   1. How will you collect the sample for the laboratory confirmation of B.T. Malaria.

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   2. Discuss with labeled diagram of any one form of parasite, present in this condition. 4+6
   b) Describe cold sterilization. Give examples. Mention five commonly used disinfectants and their recommended concentration. 5+5
   c) Briefly describe the mechanism of anaphylaxis. Enumerate the chemical mediators released in such reactions with their significant roles. 5+5
   



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3. Write short notes on: 5+5
   1. Type II Hypersensitivity.
   2. Importance of properly labeled sample and adequate information in requisition form.
   
   



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4. Explain the following statements: 5 x 4
   1. Clinical manifestations of acute rheumatic fever develop after 3 weeks following streptococcal sore throat.
   2. A knowledge about endemic titre is important to interpret the result of Widal Test.
   3. For lab diagnosis of dengue, duration of fever has got immense importance.
   4. All morphological forms of P. falciparum are not usually detected in peripheral blood smear.
   5. Ascariasis can lead to development of acute abdomen.

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5. Choose the correct option for each of the following: 10 x 1
   1. Which strategy is followed for the diagnosis of HIV infection in an asymptomatic individual:
      1. Strategy I.
      2. Strategy II A.

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      3. Strategy II В.
      4. Strategy III.
   2. Cryptococcus neoformans is a
      1. Dimorphic fungus.
      2. True yeast.

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      3. Yeast like fungus.
      4. Mould.
   3. All are antigen presenting cell except:
      1. Dendritic cell.
      2. B lymphocyte.

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      3. Macrophage.
      4. Cytotoxic T lymphocyte.
   4. Influenza virus contains the following antigens:
      1. Haemaglutinin.
      2. Neuraminidase.

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      3. M protein.
      4. All of the above.
   5. Which one is incorrect statement in relation to mutual drug resistance:
      1. Resistance to one drug at a time.
      2. Low degree of resistance.

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      3. Resistance is not transferable to other organism.
      4. Resistance cannot be prevented by combination of drugs.
   6. All of the following are examples of device associated infection (DAI) except:
      1. VAP
      2. SSI.

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      3. CRBSI.
      4. CAUTI.
   7. All of the following are examples of agglutination reaction except:
      1. Paul Bunnel test.
      2. Weil-Felix reaction.

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      3. Widal test.
      4. Kahn test.
   8. All of the following are examples of transport media except:
      1. Cary Blair media.
      2. Venkatraman - Ramakrishnan media.

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      3. Thioglycollate broth.
      4. Autoclaved sea water.
   9. Polar flagella is found in following bacteria:
      1. Salmonella.
      2. Staphylococcus.

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      3. Pseudomonas.
      4. Brucella.
   10. Selective media for Pseudomonas is:
       1. Cetrimide agar.
       2. MYP agar.

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       3. Mannitol salt agar.
       4. XLD agar.
   
   

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