Download MBBS 2nd Year WBUHS MBBS Pathology Paper II 2023 March April Question Paper

Full Marks : 100

Time : 3 hours

Attempt all questions. The figures in the margin indicate full marks.

1. a) A 6 year old boy developed puffiness of face, oliguria and mild hypertension two weeks after an attack of sore throat. 2+5+5+3
   1. What is the provisional diagnosis?
   2. What is the pathogenesis of the condition?

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   3. What laboratory investigations to be done to confirm the diagnosis?
   4. Mention the fates of this condition.
   b) A 65 year old male smoker developed cough, occasional hemoptysis and marked weight loss in 4-6 weeks. Chest X-ray shows an opacity in right upper lobe. On examination one moderately enlarged, firm lymph node was found over the neck. 1+5+6+3
   1. What may be the provisional diagnosis?
   2. How will you proceed for a quick confirmation of your suspicion?
   3. How will you classify this condition histologically?

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   4. What may be the complications in this case?
2. Answer the following: 3×10
   1. Describe the pathogenesis of carcinoma of cervix.
   2. Describe the pathogenesis of peptic ulcer.
   3. Discuss the pathogenesis of nodular hyperplasia of prostate.

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3. Write short notes on: 2x5
   1. Leiomyoma of uterus.
   2. Pleomorphic salivary adenoma.
4. Explain the following statements: 5×4
   1. Crohn's disease and ulcerative colitis have macroscopic and microscopic differences.

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   2. Phyllodes tumor of breast is not always benign in behaviour.
   3. Alcoholism is not always a pre-requisite for cirrhosis.
   4. Diagnostic features of carcinoid tumour are specific.
   5. Sequestrum leads to involucrum formation.

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5. Choose the correct option for each of the following: 10x1
   1. The cardinal features of Tetralogy of Fallot include all of the followings except:
      1. Atrial septal defect.
      2. Ventricular septal defect.
      3. Obstruction to right ventricular outflow tract.
      4. Right ventricular hypertrophy.

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   2. Which of the following statements is true for renal cell carcinoma:
      1. It is not related to cigarette smoking.
      2. Clear cell type of RCC is usually hereditary.
      3. Most likely arise from glomerular epithelial cells.
      4. Its characteristic tendency is to invade the renal vein.

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   3. In Rheumatoid Arthritis, bone resorption is contributed by which cytokine?
      1. IFN-gamma.
      2. IL-17.
      3. RANKL.
      4. TNF.

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   4. Modified macrophages of brain are:
      1. Schwann cell.
      2. Microglia.
      3. Astrocytes.
      4. Ganglion.

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   5. Emphysema associated most with alpha I antitrypsin deficiency is:
      1. Panacinar.
      2. Centriacinar.
      3. Distal acinar.
      4. Irregular.

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   6. Long standing cases of Crohn's disease may develop the following complications except:
      1. Malabsorption.
      2. Toxic megacolon.
      3. Fistula formation.
      4. Stricture formation.

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   7. Arias stella reaction occurs in:
      1. Ectopic tubal gestation only.
      2. All ectopic gestations.
      3. Uterine gestation.
      4. Uterine as well as ectopic gestation.

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   8. Astrocytoma occurring in children is commonly:
      1. Fibrillary.
      2. Pilocytic.
      3. Anaplastic.
      4. Glioblastoma multiforme.

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   9. Krukenberg's tumour may have all primary tumours listed below except:
      1. Breast.
      2. Stomach.
      3. Liver.
      4. Pancreas.

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   10. In an undescended testis, the following tumor develops most often :
       1. Seminoma.
       2. Teratoma.
       3. Choriocarcinoma.
       4. Yolk sac tumor.

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