Download GTU BE/B.Tech 2019 Summer 6th Sem New 2160401 Advanced Molecular Biology Ii Question Paper

Download GTU (Gujarat Technological University) BE/BTech (Bachelor of Engineering / Bachelor of Technology) 2019 Summer 6th Sem New 2160401 Advanced Molecular Biology Ii Previous Question Paper

1
Seat No.: ________ Enrolment No.___________
GUJARAT TECHNOLOGICAL UNIVERSITY
BE - SEMESTER ?VI(NEW) ? EXAMINATION ? SUMMER 2019
Subject Code:2160401 Date:10/05/2019
Subject Name:Advanced Molecular Biology-II
Time:10:30 AM TO 01:00 PM Total Marks: 70
Instructions:
1. Attempt all questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

MARKS

Q.1 (a) Explain mismatch repair. 3
(b) What are types of mutation? 4
(c) How can detection and selection of mutants be done? 7



Q.2 (a) What is epistasis? 3
(b) What is SOS response? 4
(c) Explain genetics of M13 virus. 7


OR

(c) What is catabolite repression? 7
Q.3 (a) Chemical mutagens. 3
(b) Explain Splicing of GU-AG intron. 4
(c) Explain positive and negative regulation of transcription 7


OR
Q.3 (a) Draw and name the genes of Lac operon system 3
(b) Write a short note on Tn3 transposon in E.coli 4
(c) Draw structure of Retrovirus and explain its life cycle. 7
Q.4 (a) Draw and name the genes of Trp operon system 3
(b) Draw and explain hairpin mechanism of strand cleavage and
integration of Tn5.
4
(c) Explain types of transposable elements. 7


OR
Q.4 (a) How does acetylation and phosphorylation help in gene
expression regulation.
3
(b) Explain FISH for physical maps. 4
(c) What are integrons? 7
Q.5 (a) Define: Allele, Genotype and phenotype. 3
(b) What is difference between linked genes and unlinked genes? 4
(c) Explain the spliciosome mediated splicing in detail. 7


OR
Q.5 (a) Write the principle of chain termination DNA sequencing. 3
(b) What is DNA fingerprinting? 4
(c) Explain Maxam-Gilbert?s Method of DNA sequencing. 7


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