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9292_2012_1_S281.doc
Rajiv Gandhi University of Health Sciences
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First Year M. Pharm Degree Examination – May 2012
[Time: 3 Hours] [Max. Marks: 100]
FORMULATION TECHNOLOGY AND VALIDATION
PAPER II
(RS 2 & RS 3)
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Q.P. CODE: 9292
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Write about various techniques involved in enhancing solubility of an API?
- Give an account on types of Baby care products and how will you formulate and evaluate baby lotion?
- Explain in detail validation procedure for Hot air oven and Autoclave?
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Write the importance of Accelerated Stability studies and how will you determine shelf life of a product?
- Describe different types of sustained release dosage forms. Add a note on the mechanism of drug release in these dosage forms.
- Describe validation of analytical procedures
- Describe different types of containers and closures for pharmaceuticals.
- Explain the importance of pre formulation studies. Describe crystal morphology and polymorphism.
- How will you carry out Dissolution testing for Tablets and capsules?
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SHORT NOTES 2 X 5 = 10 Marks
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- Write a note on classification of drugs pharmaceutical classification system and show how permeability for API can be improved?
- Discuss in detail about various Legislations for cosmetic products
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