Rajiv Gandhi University of Health Sciences, Karnataka
First Year M. Pharm Degree Examination – May 2016
Time: Three Hours
--- Content provided by FirstRanker.com ---
Max. Marks: 100 Marks
BIOPHARMACEUTICS AND PHARMACOKINETICS
(Revised Scheme 4)
Q.P. CODE: 9338
Your answers should be specific to the questions asked.
--- Content provided by FirstRanker.com ---
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
2 x 20 = 40 Marks
- Discuss the various factors affecting drug absorption.
- Derive an expression for calculating various pharmacokinetic parameters for a drug administered as I.V infusion and follows one compartment kinetics.
- Explain the determination of various pharmacokinetic parameters in multiple dosing with respect to I.V and oral route.
--- Content provided by FirstRanker.com ---
SHORT ESSAYS (Answer any FIVE)
5 x 10 = 50 Marks
- Describe the various in vitro dissolution testing models.
- Discuss any two methods for the estimation of Km and Vmax.
- Explain the protocol for bioequivalence studies
- Explain Phase I reactions in biotransformation of drugs.
- Explain the method of residuals to determine the absorption rate constant. Mention its limitations.
- Discuss MRT for various compartment models.
--- Content provided by FirstRanker.com ---
SHORT NOTES
2 x 5 = 10 Marks
- Plasma Proteins
- Concept of Clearance
--- Content provided by FirstRanker.com ---
For more, visit: FirstRanker.com
This download link is referred from the post: RGUHS M.Pharm Last 10 Years 2011-2021 Previous Question Papers || Rajiv Gandhi University of Health Sciences
--- Content provided by FirstRanker.com ---