Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - MAY 2016
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[Time: 3 Hours] [Max. Marks: 100]
Molecular Biology
(Revised Scheme 4)
Q.P. CODE: 9351
Your answers should be specific to the questions asked.
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Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- What is gene mapping? Explain principle and process of mapping of any two human disease genes.
- Explain the principle, process and applications of gene cloning.
- Explain in detail how the signaling and communication take place between cells and their environment. Add a note on third messengers.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- What are the elements that control gene expression?
- Explain the structure and functions of plasma membrane.
- Explain the principle and applications of MTT assay.
- What is apoptosis? Explain various events and regulation of apoptosis.
- Write a note on gene therapy.
- Write notes on peptide chemistry and peptidomimetics.
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SHORT NOTES 2 X 5 = 10 Marks
- Explain principle and applications of western blotting assay.
- Write a note on nucleic acid technologies.
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