Rajiv Gandhi University of Health Sciences, Karnataka
First Year M. Pharm Degree Examination – NOV 2016
Time: Three Hours
--- Content provided by FirstRanker.com ---
Max. Marks: 100 Marks
MEDICINAL CHEMISTRY-II (Natural Products)
(Revised Scheme 4)
Q.P. CODE: 9348
Your answers should be specific to the questions asked.
--- Content provided by FirstRanker.com ---
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 20 = 40 Marks
- a) Describe in detail the theoretical and practical aspects of microbial conversions.
b) Enumerate the different reactions possible by microbial conversions. (10+10) - a) Describe the significance of structural features, mechanism of action and classification of a) Cephalosporins b) Other β lactam antibiotics.
--- Content provided by FirstRanker.com ---
b) Show how the structure of emetine has been arrived at. (10+10) - a) Describe the physiological role of sex hormones. Write their structures. Describe the SAR and development of anabolic agents for treatment of infertility.
b) Classify adrenal cortex hormones; give their therapeutic role. Discuss the structural modifications done to obtain useful medicinal agents. (12+8)
SHORT ESSAYS (Answer any FIVE) 5 x 10 = 50 Marks
- Depict the metabolism of Purines and Pyrimidines
- Establish the structure of Morphine.
- Discuss the chemistry of vitamin B1 with suitable illustrations.
- Describe the chemistry and development of β -lactamase stable cephalosporins.
- Describe the chemistry of carotenoids and discuss the constitution of Vitamin A.
- Elucidate the structure of Reserpine.
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
SHORT NOTES 2 x 5 = 10 Marks
- Describe the chemistry and MOA of antiparasitic Purine and Pyrimidine related compounds.
- Discuss the biosynthesis and structure of Vitamin D.
*****
--- Content provided by FirstRanker.com ---
This download link is referred from the post: RGUHS M.Pharm Last 10 Years 2011-2021 Previous Question Papers || Rajiv Gandhi University of Health Sciences
--- Content provided by FirstRanker.com ---