Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - NOV 2016
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Advanced Pharmacology and Toxicology
(Revised Scheme 4)
Q.P. CODE: 9349
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
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LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- What is cardiac arrhythmia? Give the classification of Anti arrhythmic drugs with example and discuss the pharmacology, toxicology and uses of Calcium channel blockers. Note on adverse reaction of quinidine.
- a) Classify Antiepileptic drugs with examples.
b) Explain the mechanism of action, therapeutic uses and adverse effects of Phenytoin and Carbamazepine. - Classify analgesics with example and describe Opioid receptors and give the pharmacology of Opioid analgesics.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Define Peptic ulcer. Classify anti-ulcer drugs.
- Explain Cardiotonics with example.
- Describe G-protein coupled receptors.
- Explain the mechanism of action of tricyclic antidepressant drugs and pathophysiology of depression.
- Give a note on ACE inhibitors.
- What is organ toxicity? What are the therapeutic drugs involved in Nephrotoxicity and Reproductive toxicity.
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SHORT NOTES 2 X 5 = 10 Marks
- Rifampicin
- Aminoglycoside antibiotics
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