RGUHS M.Pharm Last 10 Years 2011-2021 Previous Question Papers || Rajiv Gandhi University of Health Sciences
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First Year M.Pharm Degree Examination - NOV 2016
[Time: 3 Hours] [Max. Marks: 100]
BIOPHARMACEUTICS AND PHARMACOKINETICS
(RS 2 & RS 3)
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Q.P. CODE : 9283
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Classify and explain dosage form related factors affecting drug absorption.
- Write a note on Phase I reactions of biotransformation.
- Deduce equations to obtain pharmacokinetic parameters of a drug administered by oral route, the drug undergoing absorption by first order kinetics and body acting as a single compartment.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- What are the causes of non-linearity?
- What are in-vitro and in-vivo methods of determining absorption?
- Write a note on measurement of bioavailability.
- Explain factors affecting excretion of drugs.
- Explain the basic concept of Therapeutic Drug Monitoring.
- Explain pH partition hypothesis.
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SHORT NOTES 2 X 5 = 10 Marks
- Discuss induction of drug metabolizing enzymes.
- How are ionic/ionizable drugs absorbed?
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