Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination - May 2011
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[Time: 3 Hours] [Max. Marks: 100]
MEDICINAL CHEMISTRY - II (NATURAL PRODUCTS)
PAPER IV
(RS 2 & RS 3)
Q.P. CODE: 9234
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Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Elucidate the structure of emetine.
- Classify semi synthetic penicillins. Give the SAR of ß-Lactam antibiotics.
- a) Classify female sex hormones with suitable examples.
b) Give the SAR of progesterone.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- a) Give the classification of cardiac-glycosides with their structures.
b) Discuss the chemical degradation of cardiac glycosides. - a) Classify adrenal cortex hormones.
b) Write the synthesis of cortisone from sermegetoanin. - Write the synthesis of reserpine.
- Give five important chemical constituents from a) Salacia reticulata b) Swertia Chirata c) Pterocarpus supium. Mention their medicinal uses.
- Write the synthesis of any three non-steroidal synthetic oestrogenic hormones. Give their medicinal importance.
- Give the chemistry of anti parasitic purine and pyrimidines related agents.
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SHORT NOTES 2 X 5 = 10 Marks
- Anti fungal agents
- Morphine derivatives and their identification tests.
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