Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination – NOVEMBER 2015
[Time: 3 Hours] ADVANCED PHARMACEUTICAL ANALYSIS PAPER IV (RS2 & RS3) [Max. Marks: 100]
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Q.P. CODE: 9294
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Define and classify the various Thermoanalytical Methods of Analysis.
- Discuss the methodology involved in Microbiological assay of Vitamin B12 and Calcium pantothenate.
- Explain the bioassay of (a) Pertusis Vaccine, (b) Diphtheria Antitoxin.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Discuss the application of Enzyme Immunoassay.
- Explain briefly the various Analytical Method Validation Parameters.
- Write the methodology involved in tests for effectiveness of Antimicrobial Preservatives.
- Explain the bioassay of rabies vaccine.
- Explain the principle and methodology involved in Pyrogen testing.
- Explain WHO guidelines for analysis of crude drugs.
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SHORT NOTES 2 X 5 = 10 Marks
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- Instrumental methods of analysis
- Analysis of heavy metals
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