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Rajiv Gandhi University of Health Sciences, Karnataka
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III Year B.Pharm Degree Examination – NOV 2017
PHARMACEUTICAL ENGINEERING
(RS - 4) Q.P. CODE: 2638
Time: Three Hours Max. Marks: 70 Marks
Your answers should be specific to the questions asked.
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Draw neat labeled diagrams wherever necessary.
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- Explain the construction and working of a forced circulation evaporator and fluid bed dryer.
- Explain the theory of centrifugation. Describe construction and working of the basket centrifuge.
- Explain the theory of liquid-liquid mixing. Write the principle and working of Silverson emulsifier.
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SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
- Write the construction and working of a freeze dryer based on sublimation.
- Explain the theory of evaporation. Mention the factors affecting rate of evaporation.
- Derive an equation for heat transmission through metal wall.
- State and explain the laws governing size reduction.
- Write the working of a ball mill explaining the importance of rpm.
- What are constant boiling mixtures? How are they separated?
- Explain the construction and working of cycloidal blower.
- Write the construction and working of a suitable crystallizer to obtain large crystals.
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SHORT ANSWERS 10 x 2 = 20 Marks
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- Differentiate centrifugal and peristaltic pump.
- Enlist the applications of molecular distillation.
- Fluid energy mill is better equipment for size reduction of thermolabile substance compared to hammer mill; substantiate the statement.
- Write the principle involved in flash distillation.
- Briefly explain sedimentation tank.
- Give an example for dimensional formula and dimensionless equation.
- Differentiate fixed and moving bed ion exchange methods.
- Explain biological corrosion.
- Why is humidity control important in pharmaceutical industries?
- Name the conveyor suitable for transporting solids a) to a long distance b) to elevate large quantity of materials in a closed condition
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