Rajiv Gandhi University of Health Sciences, Karnataka

III Year Pharm-D Degree Examination – NOV 2016

Time: Three Hours                              Max. Marks: 70 Marks

PHARMACOLOGY –II

Q.P. CODE: 2861

Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary.

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LONG ESSAYS (Answer any two)                                                                   2 x 10 = 20 Marks

1. Classify anti-malarial drugs with examples. Add a note on mefloquine and artemisinin derivatives
2. Explain RNA processing in detail
3. Classify diuretics with examples. Explain the pharmacology of loop diuretics

SHORT ESSAYS (Answer any six)                                                                   6 x 5 = 30 Marks

4. Write a note on 'lac operon'
5. Explain briefly about the various `altered gene functions'

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6. Explain 'flow of genetic information'
7. Adverse effects and uses of aminoglycosides
8. Write a note on 'Biosensors'
9. Explain the pharmacology of Vinca alkaloids
10. Write a note on chronic toxicity studies

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11. Write the pharmacology of acyclovir

SHORT ANSWERS                                                                   10 x 2 = 20 Marks

12. Gene sequencing
13. Adverse effects of warfarin
14. Therapeutic uses of clopidogrel
15. JNK pathway of signal transduction

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16. Structure of chromosome
17. Tazobactam
18. Name four immunostimulants
19. Name four macrolide antibiotics
20. Mechanism of action of methotrexate

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21. Distinguish between thrombolytics and anticoagulants

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