Download RGUHS Pharm-D 3rd Semester 2014 Jan 2865 Medicinal Chemsitry Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) Pharm.D (Doctor of Pharmacy) 3rd Semester 2014 Jan 2865 Medicinal Chemsitry Question Paper.

Rajiv Gandhi University of Health Sciences, Karnataka
III Year Pharma-D Degree Examination ? Jan 2014

Time: Three Hours Max. Marks: 70 Marks

MEDICINAL CHEMSITRY

Q.P. CODE: 2865

Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary

LONG ESSAYS 2 x 10 = 20 Marks
1.
What are antihypertensive agents? Classify them giving examples. Give the synthetic route
of propranolol.
2.
Discuss SAR of tetracyclines. Give their mechanism of action.
3
Classify local anti-infective agents with examples. Write the SAR and mechanism of action
of alcohols.

SHORT ESSAYS 6 x 5 = 30 Marks
4.
Explain the chemical degradation reactions of penicillins.
5.
Write about the lipophilic parameters used in QSAR.
6.
Discuss the chemistry and mechanism of action of antifungal antibiotics.
7.
Write briefly about the chemistry and mechanism of action of anticoagulants.
8.
Give the synthesis and uses of: (i) Furosemide (ii) Chloroquine.
9.
Write an account on folate reductase inhibitors.
10.
Discuss the chemistry and therapeutic uses of glucocorticoids.
11.
Classify antiviral agents. Give the mechanism of action of zidovudine.

SHORT ANSWERS 10 x 2 = 20 Marks
12.
Write any two structures and uses of vasodilators.
13.
Define prodrug with an example.
14.
What is synergism? Give example.
15.
Beta lactamase inhibitors
16.
Drug drug interaction of quinolone antibacterials
17.
Give the synthesis and uses of metronidazole.
18.
What is crystalluria? How to overcome it?
19.
Sulfonamides used in burn therapy.
20.
Give the structure and mechanism of action of enalapril.
21.
Outline the synthetic route for ethacrynic acid.

*****
FirstRanker.com - FirstRanker's Choice