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Rajiv Gandhi University of Health Sciences, Karnataka
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I Year Pharma-D Examination – Mar 2013
Time: Three Hours
Max. Marks: 70 Marks
MEDICAL BIOCHEMISTRY
Q.P. CODE: 2853
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Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- What are enzymes & coenzymes? Classify them with examples. Give the importance of Michaelis - Menten equation in enzyme kinetics
- Discuss in detail catabolism of any three Aminoacids
- Write the biochemical reactions involved in TCA cycle along with the energetics
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SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
- Discuss various types of enzyme inhibitions with examples
- Discuss in detail Glycogenesis & Glycogenolysis
- Write the various stages of urea cycle
- What are Lipoproteins? Give its composition & functions
- Describe the principle & methodology in the determination of hormones by RIA
- What is Hyperchloremic acidosis? Give the clinical importance of low & high serum chloride levels. Write the principle & reactions involved in the estimation of chlorides in various biological samples
- Discuss in detail various types of Jaundice and formation of Bile pigments
- Add a note on metabolism of purine nucleotides
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SHORT ANSWERS 10 x 2 = 20 Marks
- Write the principle involved in the estimation of creatinine in urine
- What is glucose tolerance test? Give its importance
- What is fatty liver? Write its clinical manifestations
- What is Hyperammonemia type 1 & Hyperammonemia type 2
- What is protein turn over & nitrogen balance
- Give the test for hepatic dysfunction
- Write the physiological importance of LDL & HDL
- Write the biochemical reactions involved in the conversion of UMP to TMP
- Write the importance of various RNAs in protein synthesis
- Differentiate between serum lipids & lipoproteins
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