Download RGUHS Pharm-D 3rd Semester 2012 Sept 2865 Medicinal Chemsitry Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) Pharm.D (Doctor of Pharmacy) 3rd Semester 2012 Sept 2865 Medicinal Chemsitry Question Paper.

Med Chem 2865_2012_2_S266.doc
Rajiv Gandhi University of Health Sciences, Karnataka
III Year Pharma-D Degree Examination ? Sep 2012

Time: Three Hours Max. Marks: 70 Marks

MEDICINAL CHEMSITRY

Q.P. CODE: 2865

Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary

LONG ESSAYS 2 x 10 = 20 Marks
1.
Define antibiotics? Classify antibiotics and give one examples of drug with structure under
each class. Write the of development of acid resistant and extended spectrum penicillins
2.
Define and classify anti?infective agents with two examples of drugs with structures under
each class. Add note on structure activity relationships of quinolones
3
Classify antimalarial agents with examples. Write the mechanism of action, synthesis and
uses of chloroquine

SHORT ESSAYS 6 x 5 = 30 Marks
4.
Write the chemistry and mechanism of action of ACE inhibitors
5.
Give four chemical structures of drugs belong to oral hypoylycemic agents and outline the
synthesis of tolbutamide
6.
Classify diuretics with examples. Write the structure activity relationships of thiazide
diuretics
7.
Classify anti-Arrhythmic agents with examples. Write the synthesis of any one anti-
Arrhythmic agent
8.
Write the mode of action, chemical structure and therapeutic use of cycloserine
9.
Justify, sulfamethoxazole and trimethoprim combination is effective in antibacterial therapy
10.
Write the method of synthesis and applications of combinatorial synthesis
11.
Explain how antimetabolities act as antineoplastic agents with suitable examples

SHORT ANSWERS 10 x 2 = 20 Marks
12.
Write the chemical structure of sulfonamide used in ophthalmic infection
13.
Write the synthesis of hexyl resorcinol
14.
Write the chemical structure and uses of testosterone
15.
Mention the types of hyperlipoproteinemia
16.
Why tetracyclines are not effective in presence of milk and metals
17.
Write the chemical structure and uses of thyroxin
18.
Define scabicide with examples
19.
Write the chemical structure and uses of diethyl stilbosterol
20.
Write the mechanism of action of amino glycoside antibiotics
21.
Define prodrug with examples

*****
FirstRanker.com - FirstRanker's Choice