Rajiv Gandhi University of Health Sciences, Karnataka
First Year Pharma-D Examination – Feb/March 2011
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Time: Three Hours
Max. Marks: 70 Marks
MEDICAL BIOCHEMISTRY
Q.P. CODE: 2853
Your answers should be specific to the questions asked
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Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- Describe in detail the various stages involved in the biosynthesis of purines and its metabolism
- What are Enzymes? Write the IUB classification of Enzymes with examples. Discuss the various factors affecting the enzyme activity
- Describe in detail the biosynthetic pathway of cholesterol
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SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
- Discuss the production of Bile pigments. Discuss in detail various types of Jaundice
- What is ELISA? Discuss the principle and various methods involved in the ELISA technique
- Discuss in detail ß oxidation of fatty acids
- Write the biochemical reactions involved in the pathway in the biological oxidation
- What is Gluconeogenesis? Write the biochemical reactions in the formation of ketone bodies and their biochemical significance
- Write in brief the various coenzymes involved
- Write the catabolism of any two
- Write in detail the kidney function tests
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SHORT ANSWERS 10 x 2 = 20 Marks
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- Discuss the various methods employed in the estimation of calcium & chlorides in the biological fluids
- What are Uncouplers of Electron Transport Chain
- What is diabetes mellitus & diabetes insipidus
- Differentiate between ketogenesis and ketolysis
- What is oxidative phosphorylation
- Write the importance of alpha ketoglutarate in Ammonia detoxification
- What is Gout? Write its clinical manifestations
- Discuss the test for excretory function of kidneys
- Differentiate between good & bad cholesterol
- What is galactose tolerance test
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