Download JNU 2020 Biotechnology (Sbth) Question Paper

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Application No:

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Exam Date: 05-Oct-2020

Exam Time: 15:00-18:00

Examination: 1. Course Code - Ph.D.

2. Field of Study - Biotechnology (SBTH)

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SECTION 1 - PART I

Question No.1 (Question Id - 9)

Which of the following compounds with the given molecular formula can show metamerism?

(A) C₄H₁₀O (Correct Answer)

(B) C₂H₆O

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(C) C₄H₈O

(D) C₆H₆O

Question No.2 (Question Id - 23)

A mass weighing 5 kg is pulled up through a rough inclined plane having an angle of 45° to the horizontal surface. If the mass has been pulled by a weightless string at an acceleration 3 cm s^-2 and the co-efficient of friction between the mass and the plane is given by 0.25 , find the pull on the string.

(A) 43.30 N

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(B) 43.45 kg m s^-1

(C) 43.30 kg m s^-1

(D) 43.45 N (Correct Answer)

Question No.3 (Question Id - 14)

How many words can be formulated by using all the letters of 'MONDAY' when the 1st letter is not 'M' ?

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(A) 120

(B) 720

(C) 240

(D) 600 (Correct Answer)

Question No.4 (Question Id - 20)

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Find the binary equivalent of the decimal number 121 :

(A) 0111 1001 (Correct Answer)

(B) 0110 1001

(C) 0101 1001

(D) 0111 1101

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Question No.5 (Question Id - 6)

The number of electrons in carbanion is :

(A) Four

(B) Five

(C) Six

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(D) Eight (Correct Answer)

Question No.6 (Question Id - 18)

Find the 7^th term of the GP series whose 1^st term is 2 and the common ratio 4:

(A) 16384

Question No.7 (Question Id - 10)

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Which of the following compound is not an aromatic compound?

(A) Compound A

(B) Compound B (Correct Answer)

(C) Compound C

(D) Compound D

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Question No.8 (Question Id - 19)

Find the determinant value of the matrix $\left[\begin{array}{ccc}3& 2& 6\\ 8& 4& 2\\ 6& 4& 12\end{array}\right]$ :

(A) 32

(B) 66

(C) 0 (Correct Answer)

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(D) 60

Question No.9 (Question Id - 17)

Find the equation of the circle which has the center on the point of intersection of the two lines 2x + y - 1 = 0 and 2y - x + 3 = 0 and a radius of 7 units.

(A) (x + 1)² + (y - 1)² = 7²

(B) (x + 1)² + (y + 1)² = 7²

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(C) (x - 1)² + (y + 1)² = 7² (Correct Answer)

(D) (x - 1)² + (y - 1)² = 7²

Question No.10 (Question Id - 12)

The straight line passing through the point (5, 2) makes an angle p/4 with the straight line 2x + 3y = 1 . The equation of the first straight line is given by :

(A) 5x + y +5=0

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(B) 5y + x - 5 = 0

(C) 5y + x - 15 = 0 (Correct Answer)

(D) 5x-y-5 = 0

Question No.11 (Question Id - 13)

An equation x² - 12x + k = 0, has two roots where one root is double the other. The value of k in the equation is :

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(A) 32 (Correct Answer)

(B) 16

(C) 9

(D) 64

Question No.12 (Question Id - 28)

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What should be the velocity of the satellite that has to be launched in the horizontal direction at a height of 600 km so that it can revolve around the earth ?

(A) 700 ms^-1

(B) 7000 ms^-1 (Correct Answer)

(C) 4900 ms^-1

(D) 490000 ms^-1

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Question No.13 (Question Id - 15)

Find the value of the integral ?₁^x(2x²-3x)dx:

(A) 0 (Correct Answer)

(B) 6

(C) 1

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(D) 9

Question No.14 (Question Id - 2)

Which of the following carbonate is more soluble in water at 298 K ?

(A) Lithium carbonate

(B) Sodium carbonate

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(C) Potassium carbonate

(D) Rubidium carbonate (Correct Answer)

Question No.15 (Question Id - 7)

Match the following:

List - I	List - II
A. Free radical	I. sp2 hybridised
B. Alkane	II. sp3 hybridised
C. Alkyne	III. sp hybridised

Choose the correct answer from the options given below :

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(A) A-I, B - II, C- III (Correct Answer)

(B) A-II, B - I, C- III

(C) A-III, B - II, C-I

(D) A-II, B - III, C-I

Question No.16 (Question Id - 3)

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Which of the following sulphate is least soluble in water?

(A) Beryllium sulphate

(B) Magnesium sulphate

(C) Calcium sulphate

(D) Barium sulphate (Correct Answer)

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Question No.17 (Question Id - 11)

If 3? = 7p, find the value of sin? - cos (2?) :

(A) (v3+1)/2 (Correct Answer)

(B) (-v3+1)/2

(C) (-v3-1)/2

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(D) (v3-1)/2

Question No.18 (Question Id - 8)

The order of carbocation stability is :

(A) Me < primary < secondary < tertiary (Correct Answer)

(B) Me > primary > secondary > tertiary

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(C) Me ˜ primary ˜ secondary < tertiary

(D) Me > primary ˜ secondary > tertiary

Question No.19 (Question Id - 29)

A condenser was designed using two glass plates having the dimension of 6 cm x 15 cm. If the relative permittivity of the glass is 7.2 and they were placed 3 mm apart calculate the capacitance of the designed capacitor. [e₀ = 8.85 x 10^-12 Fm^-1]

(A) 191.16 x 10^-10 F

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(B) 1.9116 pF

(C) 191.16 pF (Correct Answer)

(D) 19.116 pF

Question No.20 (Question Id - 1)

Electronegativity of an element is related to :

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(A) Effective nuclear charge

(B) Size of the atom

(C) Oxidation state

(D) Non-metallic character (Correct Answer)

Question No.21 (Question Id - 26)

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A train that was approaching towards the station at a velocity of 90 km/hr sounds a whistle with a frequency 900 Hz. What will be the apparent frequency of the whistle to a person standing at the station (Velocity of sound 332 ms^-1)?

(A) 973.29 Hz (Correct Answer)

(B) 885.25 Hz

(C) 543.6 Hz

(D) 1025.23 Hz

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Question No.22 (Question Id - 5)

Which of the following ligand can form a chelate ?

(A) Chloride

(B) Cyanide

(C) Amine

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(D) Oxalate (Correct Answer)

Question No.23 (Question Id - 27)

A metal ball weighing 1 kg is taken out of a furnace and immersed in a copper vessel of mass 200 g containing water of mass 500 g at 40° C. If the temperature of the water rises to 50° C calculate the temperature of the furnace.

[Sp heat capacity of the metal : 168 J kg^-1 K^-1, Sp heat capacity of copper : 420 J kg^-1 K^-1, Sp heat capacity of the water : 4200 J kg^-1 K^-1]

(A) 280°C

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(B) 360°C

(C) 140°C

(D) 180°C (Correct Answer)

Question No.24 (Question Id - 22)

A wire of length 2.5 m and a diameter of 0.5 mm is stretched by 1.4 mm when a load of 2.5 kg was hanged on it. Calculate the Young's modulus of the wire (g = 9.8 ms^-2):

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(A) 2.23 x 10¹¹ N

(B) 2.23 x 10⁵ N m^-2

(C) 2.23 x 10⁵ N

(D) 2.23 x 10¹¹ N m^-2 (Correct Answer)

Question No.25 (Question Id - 24)

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A child plays with a bubble maker and blows a bubble of a diameter of 4 cm. Find the total work done if the bubble has a surface tension 0.02 N m^-1.

(A) 2.0096 x 10^-4 J (Correct Answer)

(B) 2.0096 x 10^-4 N m²

(C) 1.0048 x 10^-4 N m²

(D) 1.0048 x 10^-4 J

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Question No.26 (Question Id - 16)

The value of log₃ log₂ log₂ 256 :

(A) log₃ 2

(B) log₂ 3

(C) 2 log₃ 2

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(D) log₃ 3 (Correct Answer)

Question No.27 (Question Id - 25)

A Carnot engine works as a refrigerator between the temperature 270 K and 330 K. If it receives 400 cal heat from the Freezing chamber calculate the amount of heat the engine has released to the higher temperature reservoir.

(A) 488.9 kcal

(B) 468.9 cal

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(C) 488.9 cal (Correct Answer)

(D) 468.9 kcal

Question No.28 (Question Id - 4)

Melting point (mp) of NaCl is 801 °C and LiCl is 605 °C. This could be explained based on the following reason :

(A) Reason 1: due to partial covalent character of LiCl, the mp is lower. (Correct Answer)

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(B) Reason 2: due to partial ionic character of LiCl, the mp is lower.

(C) Reason 3: Due to lower atomic number of LiCl, the mp is lower.

(D) Reason 4: Due to smaller size of Li, the mp is lower.

Question No.29 (Question Id - 21)

The angle between the two vectors a=2i+6j and b=4i+8j is given by:

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(A) tan^-1 (5/7)

(B) tan^-1 (1/7) (Correct Answer)

(C) cos^-1 (3/5v2)

(D) cos^-1 (1/5v2)

Question No.30 (Question Id - 30)

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The Equation of an alternating e.m.f is 25 sin 50 pt. The mean value and the rms value are given by:

(A) E mean = 31.84 V E rms = 17.68 V

(B) E mean = 15.92 V E rms = 35.36 V

(C) E mean = 31.84 V E rms = 35.36 V

(D) E mean = 15.92 V E rms = 17.68 V (Correct Answer)

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SECTION 2 - PART II

Question No.1 (Question Id - 146)

The following reaction is an example of which type of metabolic reaction.

(A) Group Transfer Reaction

(B) Isomerization (Correct Answer)

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(C) Rearrangement

(D) Elimination

Question No.2 (Question Id - 53)

The dissociation constant for the binding of ligand A to a protein P was observed to be 0.001 M at 37°C. The free energy change upon binding of A to P would be nearly :

(A) - 1.0 kcal/mol

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(B) - 1.8 kcal/mol

(C) + 2.4 kcal/mol

(D) -4.2 kcal/mol (Correct Answer)

Question No.3 (Question Id - 87)

Which of these immunoglobulins can form a dimer ?

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(A) IgG

(B) IgA (Correct Answer)

(C) IgM

(D) IgD

Question No.4 (Question Id - 134)

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Del factor in sterilization process is a measure of :

(A) Fractional reduction in viable organism count (Correct Answer)

(B) Fractional increase in viable organism count

(C) Fractional activation energy of the process

(D) Fractional reduction in nutrient degradation constant

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Question No.5 (Question Id - 128)

The database used in tblastX consists of :

(A) Protein

(B) DNA (Correct Answer)

(C) RNA

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(D) None of the above

Question No.6 (Question Id - 93)

Which one of the following lipids can be expected to be preferentially associated with lipid rafts ?

(A) Phosphatidylethanolamine

(B) Phosphatidic acid

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(C) Lysophosphatidic acid

Question No.7 (Question Id - 79)

How does genetically wall-less bacteria mycoplasma stain with Gram stain ?

(A) Gram positive

(B) Gram negative (Correct Answer)

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(C) Pseudo Gram Positive

(D) No color

Question No.8 (Question Id - 40)

In the following resonance structures, which statement is correct with respect to stability?

(A) Form A is more stable than the others (Correct Answer)

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(B) Form B is more stable than the others

(C) Form C is more stable than the others

(D) All forms are equally stable. Because these are resonance forms.

Question No.9 (Question Id - 100)

Given below are two statements :

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Statement I:

High cholesterol in the blood contributes to the formation of atherosclerosis plaques in the blood vessels

Statement II :

Individuals with defective LDL receptor gene have increased risk of a heart attack

In the light of the above statements, choose the correct answer from the options given below :

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(A) Both Statement I and Statement II are correct (Correct Answer)

(B) Both Statement I and Statement II are incorrect

(C) Statement I is correct but Statement II is incorrect

(D) Statement I is incorrect but Statement II is correct

Question No.10 (Question Id - 137)

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In the cross-flow filtration technique, the flow of liquid across the membrane is not affected by :

(A) Temperature

(B) Viscosity

(C) Pressure

(D) Gravitational constant (Correct Answer)

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Question No.11 (Question Id - 125)

Given below are two statements, one is labelled as Assertion A and the other is labelled as Reason R

Assertion A:

HMM is more sensitive than PSI-BLAST

Reason R:

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PSI-BLAST specify a full probabilistic model which makes it slow

In the light of the above statement, choose the correct answer from the options given below :

(A) Both A and R are true and R is the correct explanation of A

(B) Both A and R are true but R is not the correct explanation of A

(C) A is true but R is false (Correct Answer)

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(D) A is false but R is true

Question No.12 (Question Id - 145)

In the arginine biosynthesis pathway shown below, mutant will not be able to catalyse that specific step depicted with the respective arrow. Which mutant will grow in the presence of Ornithine ?

Precursor ? Ornithine ? Citrulline ? Arginine

Mutant 1 Mutant 2 Mutant 3

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(A) Mutant 1 (Correct Answer)

(B) Mutant 2

(C) Mutant 3

(D) Mutant 2 and 3

Question No.13 (Question Id - 148)

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The energy required to destabilize existing chemical bonds is called ___________ energy.

(A) activation (Correct Answer)

(B) destabilization

(C) kinetic

(D) free

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Question No.14 (Question Id - 130)

The broad subject area that captures and visualizes the sequence variation that occurs in homologous DNA, RNA, or protein molecules:

(A) Maximum parsimony

(B) Sequence Alignment

(C) Structural Bioinformatics

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(D) Molecular Phylogeny (Correct Answer)

Question No.15 (Question Id - 77)

Thermoplasma can grow at high temperature over 85°C because their membranes are stable due to presence of:

(A) Bilayer of C20 diethers

(B) C40 tetraether monolayer (Correct Answer)

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(C) C20 diester hydrocarbon chains

(D) C40 tetraester hydrocarbon

Question No.16 (Question Id - 81)

Which cytokine plays a role in both the innate and adaptive immunity ?

(A) TNF

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(B) IL-2

(C) IL-12

(D) IFN-? (Correct Answer)

Question No.17 (Question Id - 89)

Which of the following constitutes a part of both the innate and adaptive immunity?

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(A) T cell

(B) B cell

(C) NK cells

Question No.18 (Question Id - 140)

For the production of recombinant protein at industrial scale using microbial systems, which of the following strategies is not well suited to achieve higher expression yields ?

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(A) Use of strong and inducible promoters

(B) Use of strong terminator (Correct Answer)

(C) Use of codon optimization strategy

(D) Use of high cell density cultivation strategy

Question No.19 (Question Id - 86)

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The immunoglobulin fold consists of a pair of :

(A) a-helices

(B) ß-sheets (Correct Answer)

(C) disordered loops

(D) a-helix and ß-sheet

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Question No.20 (Question Id - 37)

Which of the following is a Lewis acid ?

(A) BF₃ (Correct Answer)

(B) HCl

(C) CH₃CO₂H

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(D) C₆H₅CO₂H

Question No.21 (Question Id - 104)

Cellular nucleases break an ester bonds present in a :

(A) Phosphomonodiester bond

(B) Phosphodiester bond (Correct Answer)

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(C) Phosphotriester bond

(D) Nucleoside unit

Question No.22 (Question Id - 121)

Orthologous sequences are defined as :

(A) Homologous sequences in the same species which have similar and often redundant functions

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(B) Homologous sequences that share little amino acid identity but share great structural similarity

(C) Homologous sequences in the same species that arose through gene duplication

(D) Homologous sequences in different species that share an ancestral gene (Correct Answer)

Question No.23 (Question Id - 91)

Which one of the following properties of a lipid molecule has a major influence on the curvature of the membrane ?

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(A) Cross section area of the head group of the lipid molecule

(B) Ratio of the cross section area of the head group to acyl chains (Correct Answer)

(C) Length of the acyl chains

(D) Saturation of the acyl chains

Question No.24 (Question Id - 82)

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The events in the generation of T cell dependent antibody responses are :

A. T: B cell interaction

B. Antigen taken up by dendritic cells and presented to T_H cells

C. B cell differentiation: IgG secretion and Isotype switching

D. Activated T cells migrate to the follicle following a chemical gradient

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E. Activated B cells migrate back to the follicle. Germinal centers are formed within the follicles and are the sites of affinity maturation and memory B cell generation.

Choose the correct order of sequence of the events from the options given below :

(A) BDACE (Correct Answer)

(B) BADCE

(C) BDCAE

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(D) BCADE

Question No.25 (Question Id - 44)

Which of the following is a high-through put approach used widely in studying biology?

(A) Mass Spectrometry (Correct Answer)

(B) Gene knockout

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(C) Side-directed mutagenesis

(D) Gel filtration

Question No.26 (Question Id - 31)

For an element which of the following property is not a measurable quantity ?

(A) Electronegativity (Correct Answer)

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(B) Electron gain enthalpy

(C) Ionization potential

(D) Atomic radius

Question No.27 (Question Id - 110)

DNA rolling circular amplification machinery is mainly utilized for replication of :

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(A) Fungal genome

(B) Animal genome

(C) Plant genome

(D) Phage genome (Correct Answer)

Question No.28 (Question Id - 66)

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Which of the following molecule is known as the glucose sensor ?

(A) Hexokinase

(B) Glucokinase

(C) Phosphorylase (Correct Answer)

(D) Phosphorylase kinase

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Question No.29 (Question Id - 69)

The most abundant organic compound in the biosphere is :

(A) Cellulose (Correct Answer)

(B) Keratin

(C) Glycogen

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(D) Glucose

Question No.30 (Question Id - 32)

Which of the following hydroxide is amphoteric in nature ?

(A) Beryllium hydroxide (Correct Answer)

(B) Magnesium hydroxide

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(C) Calcium hydroxide

(D) Barium hydroxide

Question No.31 (Question Id - 132)

Determine the specific growth rate (µ) of the microorganism having a doubling time of 45 minutes:

(A) 0.75 h^-1

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(B) 0.52 h^-1

(C

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