(LQ 4269) FEBRUARY 2020 Sub. Code: 4269
B.PHARM. DEGREE EXAMINATION
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FOURTH YEARPAPER III ? PHARMACOLOGY - II
Q.P. Code: 564269
Time: Three hours Maximum: 100 Marks
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I. Elaborate on: (2 x 20 = 40)1. Classification of anti-tubercular drugs. Describe briefly mechanism of action
adverse drug reaction, and r apeutic uses of Isoniazid.
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2. a) Classify antihistamine drugs, discuss the mechanism of action, rapeutic usesand adverse effects of first generation H
1
receptor antagonist.
b) What are advantag es of second generation H
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1receptor antagonist?
II. Write notes on: (8 x 5 = 40)
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1. Proton pump inhibitors and its uses.2. Write notes on Metronidazole.
3. Write symptoms and trea tment of Lead poisoning.
4. Drugs used in th erapy of Migraine.
5. Write briefly on role of Fibri nolysis in Cardiovascular diseases.
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6. Discuss third generation Cephalosporin.7. Describe biological cloc ks and ir significance.
8. Advantages and disadvantages of Radioactive Iodine.
III. Short answers on: (10 x 2 = 20)
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1. Rationale of using prostaglandin analogue in peptic ulce
2. Adverse effects of Tetracycline.
3. Name two drugs used in Hepatitis and mention ir comm on adverse effects.
4. Comment usefulness of Sulfasalaz ine in inflammatory bowel disease.
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5. What is post marketing surveillance?6. Drugs for erectile dysfunction.
7. Role of substance ?P?.
8. Mention r apeutic uses of Mifepristone.
9. Name two antifungal antibiotics.
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10. Give example for parenteral Iron supplements.*******
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