Professional Examination 2018
MBBS
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Subject: Pharmacology-1
Instructions:
- All questions are compulsory.
- Write the question number once only.
- MCQ question paper.
- Use blue/black ball point pen only.
- Mark the answer with a dark ink. If he/she overwrites/strikes or put white ink on the cross once marked, it will not be evaluated.
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Time: 30 Minutes
Total MCQs: 16
1. If a drug has short duration of action, the action can be prolonged by all except:
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- Enteric coating
- Interfering with renal excretion
- Inhibiting drug metabolism
2. Following are pro drugs except:
- Enalapril
- Ranitidine
- Levodopa
- Sulindac
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3. Which of the following factor is most commonly related to the selection of dosage?
- Age
- Sex
- Weight
- Body surface area
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4. After prolonged treatment following drugs should be gradually withdrawn (except):
- Clonidine
- Alpha methyl dopa
- Chlorthiazide
- Prednisolone
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5. Following are the effect of the Acetylcholine (except):
- Constriction of bronchi
- Increase of heart rate
- Increased peristalsis
- Miosis
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6. Which of the following drug is most suitable for the treatment of Myasthenia Gravis?
- Physostigmine
- Atropine
- Pyridostigmine
- Pralidoxime
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7. Noradrenaline release is controlled by:
- Presynaptic autoreceptors
- Postsynaptic receptors
- Nucleic receptors
- Silent receptors
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8. Which antihypertensive agent is used for management of hypertensive emergencies?
- Prazosin
- Glyceryl trinitrate
- Verapamil
- Atenolol
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9. Ankle oedema produced by Amlodipine is:
- Permanent
- Resistant to diuretic
- Relieved by diuretics
- Observed in all patients
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10. Fenofibrates actions exclude:
- Reduce triglyceride level
- Increase HDL-C level
- Decrease lipoprotein lipase activity
- Decrease LDL level
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11. Spironolactone and ACE inhibitors are not used concurrently because of danger of:
- Hyperglycemia
- Hyperkalemia
- Hypokalemia
- Hypoglycemia
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12. All of the following antihistaminic has anticholinergic action except:
- Cetrizin
- Promethazine
- Diphenhydramine
- Cyproheptadine
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13. Drugs used for prophylaxis of migraine are - all except:
- B-blocker
- NSAID
- Tricyclic antidepressant
- Flunarizine
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14. Regarding peripherally acting muscle relaxants all are correct except:
- Given IV
- Used for short term purposes
- Blocks Neuromuscular transmission
- Causes CNS depression
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15. Sucralfate acts by:
- Acting against Pylon
- Physical barrier
- As antacid
- Decreasing acid secretion
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16. Stimulant purgative is contraindicated in:
- Pregnancy
- Preparation of bowel
- With anthelmintics
- Atonic constipation
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