Download Hemwati Nandan Bahuguna Uttarakhand Medical Education University (HNBUMU) Medical Entrance Exam 2020 Jan Biochemistry Question Paper With Answer Previous Question Paper With Solution
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Biochemistry??? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place?:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Biochemistry??? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place?:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
1. Two Vitamin whose derivatives are involved in transformation of serine to glycine
are:
a. ?B
6
?ad?B
12
?
b. ?B
12
?and?nicotinamie?
c. ?Folic?acid?and?B
6
?
d. ?Folic?acid?and?B
12
?
2. Which vitamin is synthesized by intestinal bacteria?
a. ?Vit?B?
b. ?Vit?A?
c. ?Vit?D?
d. ?Vit?K?
3. Which vitamin is related to a co-factor in glycine metabolism is:
a. ?Vit?E?
b. ???Folic?acid?
c. ?Thiamine?
d. ?Cobalamine?
4. Biological activity of tocopherols has been attributed, in part to their actions as:
a. ?Antioxidant?
b. ?Anticoagulants?
c. ?Provitamin?
d. ?Antidotes?for?selenium?poisoning?
5. Vitamin C is present in largest amount in the body in:
a. ?Eye?
b. ?Kidneys?
c. ?Testes?
d. Adrenal?cortex?
?
6. The following vitamin is important in non-oxidative decarboxylation,
transamination and transsulfuration reactions:
a. ?Riboflavin?
b. ?Thiamine?
c. ?Pyridoxine?
d. ?Pantothenic?acid?
?
7. Most of vitamin B
12
in the body is stored as:
a. ?Methyl?B
12
?
b. ?Hydroxy?B
12
?
c. ?Cyano?cobalamine?
d. ?None?of?the?above?
?
8. Beri-beri is caused due to the deficiency of:
a. ?Thiamine?
b. Pyridoxine?
c. ?Ascorbic?acid?
d. ?Riboflavin?
?
9. Which of the following is not true of Vit D?
a. ?Its?active?form?is?calcitriol?
b. ?Increase?calcium?absorption?from?the?intestines?
c. ?Its?deficiency?results?in?rickets?
d. ?Its?decrease?cause?phosphate?reabsorption?from?the?kidneys?
?
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Biochemistry??? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place?:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
1. Two Vitamin whose derivatives are involved in transformation of serine to glycine
are:
a. ?B
6
?ad?B
12
?
b. ?B
12
?and?nicotinamie?
c. ?Folic?acid?and?B
6
?
d. ?Folic?acid?and?B
12
?
2. Which vitamin is synthesized by intestinal bacteria?
a. ?Vit?B?
b. ?Vit?A?
c. ?Vit?D?
d. ?Vit?K?
3. Which vitamin is related to a co-factor in glycine metabolism is:
a. ?Vit?E?
b. ???Folic?acid?
c. ?Thiamine?
d. ?Cobalamine?
4. Biological activity of tocopherols has been attributed, in part to their actions as:
a. ?Antioxidant?
b. ?Anticoagulants?
c. ?Provitamin?
d. ?Antidotes?for?selenium?poisoning?
5. Vitamin C is present in largest amount in the body in:
a. ?Eye?
b. ?Kidneys?
c. ?Testes?
d. Adrenal?cortex?
?
6. The following vitamin is important in non-oxidative decarboxylation,
transamination and transsulfuration reactions:
a. ?Riboflavin?
b. ?Thiamine?
c. ?Pyridoxine?
d. ?Pantothenic?acid?
?
7. Most of vitamin B
12
in the body is stored as:
a. ?Methyl?B
12
?
b. ?Hydroxy?B
12
?
c. ?Cyano?cobalamine?
d. ?None?of?the?above?
?
8. Beri-beri is caused due to the deficiency of:
a. ?Thiamine?
b. Pyridoxine?
c. ?Ascorbic?acid?
d. ?Riboflavin?
?
9. Which of the following is not true of Vit D?
a. ?Its?active?form?is?calcitriol?
b. ?Increase?calcium?absorption?from?the?intestines?
c. ?Its?deficiency?results?in?rickets?
d. ?Its?decrease?cause?phosphate?reabsorption?from?the?kidneys?
?
10. The action of vitamin K in formation of clotting factor is through:
a. ?Post?transcription?
b. ?Post?translation?
c. ?Golgi?complex?
d. ?Endoplasmic?reticulum?
?
11. Specific disease caused by vitamin B
1
deficiency
a. ?Pellagra?
b. Angular?cheilitis?
c. ?Megaloblastic?anemia?
d. ?Peripheral?polyneuritis?
?
12. Deficiency of vitamin A causes the following except:
a. ?Night?blindness?
b. ?Corneal?dryness?
c. ?Bitot's?spots?
d. ?Myopia?
?
13. Active form of vitamin D in kidney is:?
a. ?1?dihydroxy?cholecalciferol?
b. ?25?hydroxy?cholecalciferol?
c. ?1,25?dihydroxy?cholecalciferol?
d. ?7?dihydroxy?calciferol?
?
14. Tertiary structure of protein is maintained by all except:
a. ?H
2
?bond?
b. ?Hydrophobic?
c. ?Ionic?bond?
d. ??None?of?the?above?
?
15. Which of the following is a derived a derived protein:
a. ?Protamines?
b. ?Peptones?
c. Prolamines?
d. ?Lactalbumin?
?
16. Quaternary structure of protein is:
a. ?The?arrangement?sequence?of?amino?acids?in?the?polypeptide?chain?
b. ?Inter?relation?between?amino?acids?in?a?single?polypeptide?chain?
c. ?Inter?relation?of?amino?acids?in?2?polypeptide?chains?
d. ?The? inter? relation? and? arrangement? of? polypeptides? in? a? protein?with? more?than? 2?
polypeptide?chains?
?
17. Indole ring is present in:
a. ?Tryptophan?
b. Valine?
c. ?Methionine?
d. ?Histidine?
?
18. The following is false about tryptophan:
a. ?Non?essential?amino?acid?
b. ?Involved?in?serotonin?synthesis?
c. Involved?in?niacin?synthesis?
d. Involved?in?melatonin?in?synthesis?
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Biochemistry??? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place?:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
1. Two Vitamin whose derivatives are involved in transformation of serine to glycine
are:
a. ?B
6
?ad?B
12
?
b. ?B
12
?and?nicotinamie?
c. ?Folic?acid?and?B
6
?
d. ?Folic?acid?and?B
12
?
2. Which vitamin is synthesized by intestinal bacteria?
a. ?Vit?B?
b. ?Vit?A?
c. ?Vit?D?
d. ?Vit?K?
3. Which vitamin is related to a co-factor in glycine metabolism is:
a. ?Vit?E?
b. ???Folic?acid?
c. ?Thiamine?
d. ?Cobalamine?
4. Biological activity of tocopherols has been attributed, in part to their actions as:
a. ?Antioxidant?
b. ?Anticoagulants?
c. ?Provitamin?
d. ?Antidotes?for?selenium?poisoning?
5. Vitamin C is present in largest amount in the body in:
a. ?Eye?
b. ?Kidneys?
c. ?Testes?
d. Adrenal?cortex?
?
6. The following vitamin is important in non-oxidative decarboxylation,
transamination and transsulfuration reactions:
a. ?Riboflavin?
b. ?Thiamine?
c. ?Pyridoxine?
d. ?Pantothenic?acid?
?
7. Most of vitamin B
12
in the body is stored as:
a. ?Methyl?B
12
?
b. ?Hydroxy?B
12
?
c. ?Cyano?cobalamine?
d. ?None?of?the?above?
?
8. Beri-beri is caused due to the deficiency of:
a. ?Thiamine?
b. Pyridoxine?
c. ?Ascorbic?acid?
d. ?Riboflavin?
?
9. Which of the following is not true of Vit D?
a. ?Its?active?form?is?calcitriol?
b. ?Increase?calcium?absorption?from?the?intestines?
c. ?Its?deficiency?results?in?rickets?
d. ?Its?decrease?cause?phosphate?reabsorption?from?the?kidneys?
?
10. The action of vitamin K in formation of clotting factor is through:
a. ?Post?transcription?
b. ?Post?translation?
c. ?Golgi?complex?
d. ?Endoplasmic?reticulum?
?
11. Specific disease caused by vitamin B
1
deficiency
a. ?Pellagra?
b. Angular?cheilitis?
c. ?Megaloblastic?anemia?
d. ?Peripheral?polyneuritis?
?
12. Deficiency of vitamin A causes the following except:
a. ?Night?blindness?
b. ?Corneal?dryness?
c. ?Bitot's?spots?
d. ?Myopia?
?
13. Active form of vitamin D in kidney is:?
a. ?1?dihydroxy?cholecalciferol?
b. ?25?hydroxy?cholecalciferol?
c. ?1,25?dihydroxy?cholecalciferol?
d. ?7?dihydroxy?calciferol?
?
14. Tertiary structure of protein is maintained by all except:
a. ?H
2
?bond?
b. ?Hydrophobic?
c. ?Ionic?bond?
d. ??None?of?the?above?
?
15. Which of the following is a derived a derived protein:
a. ?Protamines?
b. ?Peptones?
c. Prolamines?
d. ?Lactalbumin?
?
16. Quaternary structure of protein is:
a. ?The?arrangement?sequence?of?amino?acids?in?the?polypeptide?chain?
b. ?Inter?relation?between?amino?acids?in?a?single?polypeptide?chain?
c. ?Inter?relation?of?amino?acids?in?2?polypeptide?chains?
d. ?The? inter? relation? and? arrangement? of? polypeptides? in? a? protein?with? more?than? 2?
polypeptide?chains?
?
17. Indole ring is present in:
a. ?Tryptophan?
b. Valine?
c. ?Methionine?
d. ?Histidine?
?
18. The following is false about tryptophan:
a. ?Non?essential?amino?acid?
b. ?Involved?in?serotonin?synthesis?
c. Involved?in?niacin?synthesis?
d. Involved?in?melatonin?in?synthesis?
?
19. Non essential amino acids are not:
a. ?Used?by?the?body?
b. Forming?part?of?the?proteins?
c. ?Required?in?the?diet?
d. ?Absorbed?in?the?intestines?
?
20. The major fuel for the brain after several weeds of starvation:
a. ?Glucose?
b. ?Fatty?acid?
c. Beta?hydroxy?butyrate?
d. ?Glycerol?
?
21. One of the following is nonessential amino acid:
a. ?Tyrosine?
b. ?Valine?
c. ?Methionine?
d. ?Cystine?
?
22. The process by which a base sequence of messenger RNA is synthesized (by a RNA
polymerase) on a template of complementary DNA is called:
a. ?Transcription?
b. ?Transduction?
c. ?Translation?
d. ?Translocation?
?
23. Hydroxylation of proline require the following except:
a. ?Fe
+2
?
b. ?O
2
?
c. ?Ascorbic?acid?
d. ?Succinate?
?
24. The process of transfer of information from the RNA to the proteins is called:
a. ?Mutation?
b. ?Translation?
c. ?Transcription?
d. ?Conjugation?
?
25. The amino acid, which is used is the estimation of collagen is:
a. ?Hydroxyproline?
b. ?Proline?
c. ?Lysine?
d. ?Glycine?
?
26. Which of the following is present in the plasma but absent in the serum?
a. ?Albumin?
b. Globulin?
c. ?Lecithin?
d. Firbinogen?
?
27. Synthesis of protein occurs on:
a. ?Mitochondria?
b. Poly?ribosomes?
c. Nucleus?
d. Golgi?bodies?
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Biochemistry??? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place?:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
1. Two Vitamin whose derivatives are involved in transformation of serine to glycine
are:
a. ?B
6
?ad?B
12
?
b. ?B
12
?and?nicotinamie?
c. ?Folic?acid?and?B
6
?
d. ?Folic?acid?and?B
12
?
2. Which vitamin is synthesized by intestinal bacteria?
a. ?Vit?B?
b. ?Vit?A?
c. ?Vit?D?
d. ?Vit?K?
3. Which vitamin is related to a co-factor in glycine metabolism is:
a. ?Vit?E?
b. ???Folic?acid?
c. ?Thiamine?
d. ?Cobalamine?
4. Biological activity of tocopherols has been attributed, in part to their actions as:
a. ?Antioxidant?
b. ?Anticoagulants?
c. ?Provitamin?
d. ?Antidotes?for?selenium?poisoning?
5. Vitamin C is present in largest amount in the body in:
a. ?Eye?
b. ?Kidneys?
c. ?Testes?
d. Adrenal?cortex?
?
6. The following vitamin is important in non-oxidative decarboxylation,
transamination and transsulfuration reactions:
a. ?Riboflavin?
b. ?Thiamine?
c. ?Pyridoxine?
d. ?Pantothenic?acid?
?
7. Most of vitamin B
12
in the body is stored as:
a. ?Methyl?B
12
?
b. ?Hydroxy?B
12
?
c. ?Cyano?cobalamine?
d. ?None?of?the?above?
?
8. Beri-beri is caused due to the deficiency of:
a. ?Thiamine?
b. Pyridoxine?
c. ?Ascorbic?acid?
d. ?Riboflavin?
?
9. Which of the following is not true of Vit D?
a. ?Its?active?form?is?calcitriol?
b. ?Increase?calcium?absorption?from?the?intestines?
c. ?Its?deficiency?results?in?rickets?
d. ?Its?decrease?cause?phosphate?reabsorption?from?the?kidneys?
?
10. The action of vitamin K in formation of clotting factor is through:
a. ?Post?transcription?
b. ?Post?translation?
c. ?Golgi?complex?
d. ?Endoplasmic?reticulum?
?
11. Specific disease caused by vitamin B
1
deficiency
a. ?Pellagra?
b. Angular?cheilitis?
c. ?Megaloblastic?anemia?
d. ?Peripheral?polyneuritis?
?
12. Deficiency of vitamin A causes the following except:
a. ?Night?blindness?
b. ?Corneal?dryness?
c. ?Bitot's?spots?
d. ?Myopia?
?
13. Active form of vitamin D in kidney is:?
a. ?1?dihydroxy?cholecalciferol?
b. ?25?hydroxy?cholecalciferol?
c. ?1,25?dihydroxy?cholecalciferol?
d. ?7?dihydroxy?calciferol?
?
14. Tertiary structure of protein is maintained by all except:
a. ?H
2
?bond?
b. ?Hydrophobic?
c. ?Ionic?bond?
d. ??None?of?the?above?
?
15. Which of the following is a derived a derived protein:
a. ?Protamines?
b. ?Peptones?
c. Prolamines?
d. ?Lactalbumin?
?
16. Quaternary structure of protein is:
a. ?The?arrangement?sequence?of?amino?acids?in?the?polypeptide?chain?
b. ?Inter?relation?between?amino?acids?in?a?single?polypeptide?chain?
c. ?Inter?relation?of?amino?acids?in?2?polypeptide?chains?
d. ?The? inter? relation? and? arrangement? of? polypeptides? in? a? protein?with? more?than? 2?
polypeptide?chains?
?
17. Indole ring is present in:
a. ?Tryptophan?
b. Valine?
c. ?Methionine?
d. ?Histidine?
?
18. The following is false about tryptophan:
a. ?Non?essential?amino?acid?
b. ?Involved?in?serotonin?synthesis?
c. Involved?in?niacin?synthesis?
d. Involved?in?melatonin?in?synthesis?
?
19. Non essential amino acids are not:
a. ?Used?by?the?body?
b. Forming?part?of?the?proteins?
c. ?Required?in?the?diet?
d. ?Absorbed?in?the?intestines?
?
20. The major fuel for the brain after several weeds of starvation:
a. ?Glucose?
b. ?Fatty?acid?
c. Beta?hydroxy?butyrate?
d. ?Glycerol?
?
21. One of the following is nonessential amino acid:
a. ?Tyrosine?
b. ?Valine?
c. ?Methionine?
d. ?Cystine?
?
22. The process by which a base sequence of messenger RNA is synthesized (by a RNA
polymerase) on a template of complementary DNA is called:
a. ?Transcription?
b. ?Transduction?
c. ?Translation?
d. ?Translocation?
?
23. Hydroxylation of proline require the following except:
a. ?Fe
+2
?
b. ?O
2
?
c. ?Ascorbic?acid?
d. ?Succinate?
?
24. The process of transfer of information from the RNA to the proteins is called:
a. ?Mutation?
b. ?Translation?
c. ?Transcription?
d. ?Conjugation?
?
25. The amino acid, which is used is the estimation of collagen is:
a. ?Hydroxyproline?
b. ?Proline?
c. ?Lysine?
d. ?Glycine?
?
26. Which of the following is present in the plasma but absent in the serum?
a. ?Albumin?
b. Globulin?
c. ?Lecithin?
d. Firbinogen?
?
27. Synthesis of protein occurs on:
a. ?Mitochondria?
b. Poly?ribosomes?
c. Nucleus?
d. Golgi?bodies?
?
28. Which of the following amino acids is quickly converted to tyrosine?
a. ?Arginine?
b. Glycinec?
c. Phenylalanine?
d. Leucine?
?
29. Alkaptonuria, an inherited metabolic disorder of L0tyrosine metabolism is due to
lack of:?
a. ?Parahydroxy?phenyl?pyruvate?Hydroxylase?
b. ?Tyrosine?transaminase?
c. ?Homogentisate?oxidase?
d. ?Tyrosine?oxidase?
?
30. During phagocytosis, the metabolic process called respiratory burst involves the
activation of:
a. ?Oxidase?
b. ?Hydrolase?
c. ?Peroxidase?
d. ?Dehydrogenase?
?
31. Heme is converted to bilirubin mainly in:
a. ?Kidney?
b. Liver?
c. ?Spleen?
d. ?Bone?marrow?
?
32. Fatty acid oxidation occurs in:
a. ?Cytoplasm?
b. ?Microsomes?
c. ?Mitochondria?
d. ?All?of?the?above?
?
33. Which of the following fatty acids are not syntehsised in human body:
a. ?Oleic,?linoleic?and?linolenic?acid?
b. ?Arachidonic,?linolenic?and?linoleic?acid?
c. ?Palmitic?Oleic?and?arachidonic?
d. ?Linoleic,?arachidonic?and?stearic?acid?
?
34. A fatty acid that is not synthesized in man is:
a. ?Linoleic?acid?
b. ?Oleic?acid?
c. ?Palmitic?acid?
d. ?Stearic?acid?
?
35. The lipoprotein particles that have the highest percentage concentration of
cholesterol is:
a. ?Chylomicron?
b. ?VLDL?(Very?low?density?lipoprotein)?
c. ?LDL?(Low?density?lipoprotein)?
d. ?HDL?(High?density?lipoprotein)?
?
?
?
?
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Biochemistry??? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place?:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
1. Two Vitamin whose derivatives are involved in transformation of serine to glycine
are:
a. ?B
6
?ad?B
12
?
b. ?B
12
?and?nicotinamie?
c. ?Folic?acid?and?B
6
?
d. ?Folic?acid?and?B
12
?
2. Which vitamin is synthesized by intestinal bacteria?
a. ?Vit?B?
b. ?Vit?A?
c. ?Vit?D?
d. ?Vit?K?
3. Which vitamin is related to a co-factor in glycine metabolism is:
a. ?Vit?E?
b. ???Folic?acid?
c. ?Thiamine?
d. ?Cobalamine?
4. Biological activity of tocopherols has been attributed, in part to their actions as:
a. ?Antioxidant?
b. ?Anticoagulants?
c. ?Provitamin?
d. ?Antidotes?for?selenium?poisoning?
5. Vitamin C is present in largest amount in the body in:
a. ?Eye?
b. ?Kidneys?
c. ?Testes?
d. Adrenal?cortex?
?
6. The following vitamin is important in non-oxidative decarboxylation,
transamination and transsulfuration reactions:
a. ?Riboflavin?
b. ?Thiamine?
c. ?Pyridoxine?
d. ?Pantothenic?acid?
?
7. Most of vitamin B
12
in the body is stored as:
a. ?Methyl?B
12
?
b. ?Hydroxy?B
12
?
c. ?Cyano?cobalamine?
d. ?None?of?the?above?
?
8. Beri-beri is caused due to the deficiency of:
a. ?Thiamine?
b. Pyridoxine?
c. ?Ascorbic?acid?
d. ?Riboflavin?
?
9. Which of the following is not true of Vit D?
a. ?Its?active?form?is?calcitriol?
b. ?Increase?calcium?absorption?from?the?intestines?
c. ?Its?deficiency?results?in?rickets?
d. ?Its?decrease?cause?phosphate?reabsorption?from?the?kidneys?
?
10. The action of vitamin K in formation of clotting factor is through:
a. ?Post?transcription?
b. ?Post?translation?
c. ?Golgi?complex?
d. ?Endoplasmic?reticulum?
?
11. Specific disease caused by vitamin B
1
deficiency
a. ?Pellagra?
b. Angular?cheilitis?
c. ?Megaloblastic?anemia?
d. ?Peripheral?polyneuritis?
?
12. Deficiency of vitamin A causes the following except:
a. ?Night?blindness?
b. ?Corneal?dryness?
c. ?Bitot's?spots?
d. ?Myopia?
?
13. Active form of vitamin D in kidney is:?
a. ?1?dihydroxy?cholecalciferol?
b. ?25?hydroxy?cholecalciferol?
c. ?1,25?dihydroxy?cholecalciferol?
d. ?7?dihydroxy?calciferol?
?
14. Tertiary structure of protein is maintained by all except:
a. ?H
2
?bond?
b. ?Hydrophobic?
c. ?Ionic?bond?
d. ??None?of?the?above?
?
15. Which of the following is a derived a derived protein:
a. ?Protamines?
b. ?Peptones?
c. Prolamines?
d. ?Lactalbumin?
?
16. Quaternary structure of protein is:
a. ?The?arrangement?sequence?of?amino?acids?in?the?polypeptide?chain?
b. ?Inter?relation?between?amino?acids?in?a?single?polypeptide?chain?
c. ?Inter?relation?of?amino?acids?in?2?polypeptide?chains?
d. ?The? inter? relation? and? arrangement? of? polypeptides? in? a? protein?with? more?than? 2?
polypeptide?chains?
?
17. Indole ring is present in:
a. ?Tryptophan?
b. Valine?
c. ?Methionine?
d. ?Histidine?
?
18. The following is false about tryptophan:
a. ?Non?essential?amino?acid?
b. ?Involved?in?serotonin?synthesis?
c. Involved?in?niacin?synthesis?
d. Involved?in?melatonin?in?synthesis?
?
19. Non essential amino acids are not:
a. ?Used?by?the?body?
b. Forming?part?of?the?proteins?
c. ?Required?in?the?diet?
d. ?Absorbed?in?the?intestines?
?
20. The major fuel for the brain after several weeds of starvation:
a. ?Glucose?
b. ?Fatty?acid?
c. Beta?hydroxy?butyrate?
d. ?Glycerol?
?
21. One of the following is nonessential amino acid:
a. ?Tyrosine?
b. ?Valine?
c. ?Methionine?
d. ?Cystine?
?
22. The process by which a base sequence of messenger RNA is synthesized (by a RNA
polymerase) on a template of complementary DNA is called:
a. ?Transcription?
b. ?Transduction?
c. ?Translation?
d. ?Translocation?
?
23. Hydroxylation of proline require the following except:
a. ?Fe
+2
?
b. ?O
2
?
c. ?Ascorbic?acid?
d. ?Succinate?
?
24. The process of transfer of information from the RNA to the proteins is called:
a. ?Mutation?
b. ?Translation?
c. ?Transcription?
d. ?Conjugation?
?
25. The amino acid, which is used is the estimation of collagen is:
a. ?Hydroxyproline?
b. ?Proline?
c. ?Lysine?
d. ?Glycine?
?
26. Which of the following is present in the plasma but absent in the serum?
a. ?Albumin?
b. Globulin?
c. ?Lecithin?
d. Firbinogen?
?
27. Synthesis of protein occurs on:
a. ?Mitochondria?
b. Poly?ribosomes?
c. Nucleus?
d. Golgi?bodies?
?
28. Which of the following amino acids is quickly converted to tyrosine?
a. ?Arginine?
b. Glycinec?
c. Phenylalanine?
d. Leucine?
?
29. Alkaptonuria, an inherited metabolic disorder of L0tyrosine metabolism is due to
lack of:?
a. ?Parahydroxy?phenyl?pyruvate?Hydroxylase?
b. ?Tyrosine?transaminase?
c. ?Homogentisate?oxidase?
d. ?Tyrosine?oxidase?
?
30. During phagocytosis, the metabolic process called respiratory burst involves the
activation of:
a. ?Oxidase?
b. ?Hydrolase?
c. ?Peroxidase?
d. ?Dehydrogenase?
?
31. Heme is converted to bilirubin mainly in:
a. ?Kidney?
b. Liver?
c. ?Spleen?
d. ?Bone?marrow?
?
32. Fatty acid oxidation occurs in:
a. ?Cytoplasm?
b. ?Microsomes?
c. ?Mitochondria?
d. ?All?of?the?above?
?
33. Which of the following fatty acids are not syntehsised in human body:
a. ?Oleic,?linoleic?and?linolenic?acid?
b. ?Arachidonic,?linolenic?and?linoleic?acid?
c. ?Palmitic?Oleic?and?arachidonic?
d. ?Linoleic,?arachidonic?and?stearic?acid?
?
34. A fatty acid that is not synthesized in man is:
a. ?Linoleic?acid?
b. ?Oleic?acid?
c. ?Palmitic?acid?
d. ?Stearic?acid?
?
35. The lipoprotein particles that have the highest percentage concentration of
cholesterol is:
a. ?Chylomicron?
b. ?VLDL?(Very?low?density?lipoprotein)?
c. ?LDL?(Low?density?lipoprotein)?
d. ?HDL?(High?density?lipoprotein)?
?
?
?
?
36. Fat provides ____% of body?s calories
a. ?40%?
b. ?30%?
c. ?50%?
d. ?75%?
?
37. The major lipids that make up the cell membrane are:
a. ?Triglycerides?
b. ?Phospholipids?
c. ?Sphingomyelins?
d. ?Fatty?acids?
?
38. The following is not a phospholipid:
a. ?Sphingomyelin?
b. ?Lecithin?
c. ?Cerebroside?
d. ?Cephalin?
?
39. Which of the following is a phospholipid:
a. ?Glycogen?
b. ?Sphingomyelin?
c. ?Prostaglandin?
d. ?Oleic?acid?
?
40. In Niemann-Pick?s disease the following substrance accumulate in CNS in excess:
a. ?Glycerophosphatides?
b. ?Phosphoinositides?
c. ?Phosphosphingosides?
d. ?Glycerosphingosides?
?
41. The lipid, which acumulates in fatty liver, is:
a. ?Triglycerides?
b. ?FFA?
c. ?Lipoprotein?
d. ?Cholesterol?
?
42. The product of oxidation of odd chainfatty acids is:
a. ?Aceto?acetyl?CoA?
b. ?Malonyl?CoA?
c. ?Propionyl?CoA?
d. ?Fumaryl?CoA?
?
43. The ketone bodies, which are excreted in diabetic ketoacidosis?
a. ?Acetoacetic?acid?and?pyruvic?acid?
b. ?Acetoacetic?acid?and?oxalocacetic?acid?
c. ?Acetoacetic?acid?and?alpha?ketoglutaric?acid?
d. ?Acetoacetic?acid?and?beta?hydroxyl?butyric?acid?
?
?
44. The precursor of cholesterol synthesis is:
a. ?Acetic?acid?
b. ?Acetyl?CoA?
c. ?Oxalo?acetic?acid?
d. ?Pyruvate?
?
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Biochemistry??? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place?:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
1. Two Vitamin whose derivatives are involved in transformation of serine to glycine
are:
a. ?B
6
?ad?B
12
?
b. ?B
12
?and?nicotinamie?
c. ?Folic?acid?and?B
6
?
d. ?Folic?acid?and?B
12
?
2. Which vitamin is synthesized by intestinal bacteria?
a. ?Vit?B?
b. ?Vit?A?
c. ?Vit?D?
d. ?Vit?K?
3. Which vitamin is related to a co-factor in glycine metabolism is:
a. ?Vit?E?
b. ???Folic?acid?
c. ?Thiamine?
d. ?Cobalamine?
4. Biological activity of tocopherols has been attributed, in part to their actions as:
a. ?Antioxidant?
b. ?Anticoagulants?
c. ?Provitamin?
d. ?Antidotes?for?selenium?poisoning?
5. Vitamin C is present in largest amount in the body in:
a. ?Eye?
b. ?Kidneys?
c. ?Testes?
d. Adrenal?cortex?
?
6. The following vitamin is important in non-oxidative decarboxylation,
transamination and transsulfuration reactions:
a. ?Riboflavin?
b. ?Thiamine?
c. ?Pyridoxine?
d. ?Pantothenic?acid?
?
7. Most of vitamin B
12
in the body is stored as:
a. ?Methyl?B
12
?
b. ?Hydroxy?B
12
?
c. ?Cyano?cobalamine?
d. ?None?of?the?above?
?
8. Beri-beri is caused due to the deficiency of:
a. ?Thiamine?
b. Pyridoxine?
c. ?Ascorbic?acid?
d. ?Riboflavin?
?
9. Which of the following is not true of Vit D?
a. ?Its?active?form?is?calcitriol?
b. ?Increase?calcium?absorption?from?the?intestines?
c. ?Its?deficiency?results?in?rickets?
d. ?Its?decrease?cause?phosphate?reabsorption?from?the?kidneys?
?
10. The action of vitamin K in formation of clotting factor is through:
a. ?Post?transcription?
b. ?Post?translation?
c. ?Golgi?complex?
d. ?Endoplasmic?reticulum?
?
11. Specific disease caused by vitamin B
1
deficiency
a. ?Pellagra?
b. Angular?cheilitis?
c. ?Megaloblastic?anemia?
d. ?Peripheral?polyneuritis?
?
12. Deficiency of vitamin A causes the following except:
a. ?Night?blindness?
b. ?Corneal?dryness?
c. ?Bitot's?spots?
d. ?Myopia?
?
13. Active form of vitamin D in kidney is:?
a. ?1?dihydroxy?cholecalciferol?
b. ?25?hydroxy?cholecalciferol?
c. ?1,25?dihydroxy?cholecalciferol?
d. ?7?dihydroxy?calciferol?
?
14. Tertiary structure of protein is maintained by all except:
a. ?H
2
?bond?
b. ?Hydrophobic?
c. ?Ionic?bond?
d. ??None?of?the?above?
?
15. Which of the following is a derived a derived protein:
a. ?Protamines?
b. ?Peptones?
c. Prolamines?
d. ?Lactalbumin?
?
16. Quaternary structure of protein is:
a. ?The?arrangement?sequence?of?amino?acids?in?the?polypeptide?chain?
b. ?Inter?relation?between?amino?acids?in?a?single?polypeptide?chain?
c. ?Inter?relation?of?amino?acids?in?2?polypeptide?chains?
d. ?The? inter? relation? and? arrangement? of? polypeptides? in? a? protein?with? more?than? 2?
polypeptide?chains?
?
17. Indole ring is present in:
a. ?Tryptophan?
b. Valine?
c. ?Methionine?
d. ?Histidine?
?
18. The following is false about tryptophan:
a. ?Non?essential?amino?acid?
b. ?Involved?in?serotonin?synthesis?
c. Involved?in?niacin?synthesis?
d. Involved?in?melatonin?in?synthesis?
?
19. Non essential amino acids are not:
a. ?Used?by?the?body?
b. Forming?part?of?the?proteins?
c. ?Required?in?the?diet?
d. ?Absorbed?in?the?intestines?
?
20. The major fuel for the brain after several weeds of starvation:
a. ?Glucose?
b. ?Fatty?acid?
c. Beta?hydroxy?butyrate?
d. ?Glycerol?
?
21. One of the following is nonessential amino acid:
a. ?Tyrosine?
b. ?Valine?
c. ?Methionine?
d. ?Cystine?
?
22. The process by which a base sequence of messenger RNA is synthesized (by a RNA
polymerase) on a template of complementary DNA is called:
a. ?Transcription?
b. ?Transduction?
c. ?Translation?
d. ?Translocation?
?
23. Hydroxylation of proline require the following except:
a. ?Fe
+2
?
b. ?O
2
?
c. ?Ascorbic?acid?
d. ?Succinate?
?
24. The process of transfer of information from the RNA to the proteins is called:
a. ?Mutation?
b. ?Translation?
c. ?Transcription?
d. ?Conjugation?
?
25. The amino acid, which is used is the estimation of collagen is:
a. ?Hydroxyproline?
b. ?Proline?
c. ?Lysine?
d. ?Glycine?
?
26. Which of the following is present in the plasma but absent in the serum?
a. ?Albumin?
b. Globulin?
c. ?Lecithin?
d. Firbinogen?
?
27. Synthesis of protein occurs on:
a. ?Mitochondria?
b. Poly?ribosomes?
c. Nucleus?
d. Golgi?bodies?
?
28. Which of the following amino acids is quickly converted to tyrosine?
a. ?Arginine?
b. Glycinec?
c. Phenylalanine?
d. Leucine?
?
29. Alkaptonuria, an inherited metabolic disorder of L0tyrosine metabolism is due to
lack of:?
a. ?Parahydroxy?phenyl?pyruvate?Hydroxylase?
b. ?Tyrosine?transaminase?
c. ?Homogentisate?oxidase?
d. ?Tyrosine?oxidase?
?
30. During phagocytosis, the metabolic process called respiratory burst involves the
activation of:
a. ?Oxidase?
b. ?Hydrolase?
c. ?Peroxidase?
d. ?Dehydrogenase?
?
31. Heme is converted to bilirubin mainly in:
a. ?Kidney?
b. Liver?
c. ?Spleen?
d. ?Bone?marrow?
?
32. Fatty acid oxidation occurs in:
a. ?Cytoplasm?
b. ?Microsomes?
c. ?Mitochondria?
d. ?All?of?the?above?
?
33. Which of the following fatty acids are not syntehsised in human body:
a. ?Oleic,?linoleic?and?linolenic?acid?
b. ?Arachidonic,?linolenic?and?linoleic?acid?
c. ?Palmitic?Oleic?and?arachidonic?
d. ?Linoleic,?arachidonic?and?stearic?acid?
?
34. A fatty acid that is not synthesized in man is:
a. ?Linoleic?acid?
b. ?Oleic?acid?
c. ?Palmitic?acid?
d. ?Stearic?acid?
?
35. The lipoprotein particles that have the highest percentage concentration of
cholesterol is:
a. ?Chylomicron?
b. ?VLDL?(Very?low?density?lipoprotein)?
c. ?LDL?(Low?density?lipoprotein)?
d. ?HDL?(High?density?lipoprotein)?
?
?
?
?
36. Fat provides ____% of body?s calories
a. ?40%?
b. ?30%?
c. ?50%?
d. ?75%?
?
37. The major lipids that make up the cell membrane are:
a. ?Triglycerides?
b. ?Phospholipids?
c. ?Sphingomyelins?
d. ?Fatty?acids?
?
38. The following is not a phospholipid:
a. ?Sphingomyelin?
b. ?Lecithin?
c. ?Cerebroside?
d. ?Cephalin?
?
39. Which of the following is a phospholipid:
a. ?Glycogen?
b. ?Sphingomyelin?
c. ?Prostaglandin?
d. ?Oleic?acid?
?
40. In Niemann-Pick?s disease the following substrance accumulate in CNS in excess:
a. ?Glycerophosphatides?
b. ?Phosphoinositides?
c. ?Phosphosphingosides?
d. ?Glycerosphingosides?
?
41. The lipid, which acumulates in fatty liver, is:
a. ?Triglycerides?
b. ?FFA?
c. ?Lipoprotein?
d. ?Cholesterol?
?
42. The product of oxidation of odd chainfatty acids is:
a. ?Aceto?acetyl?CoA?
b. ?Malonyl?CoA?
c. ?Propionyl?CoA?
d. ?Fumaryl?CoA?
?
43. The ketone bodies, which are excreted in diabetic ketoacidosis?
a. ?Acetoacetic?acid?and?pyruvic?acid?
b. ?Acetoacetic?acid?and?oxalocacetic?acid?
c. ?Acetoacetic?acid?and?alpha?ketoglutaric?acid?
d. ?Acetoacetic?acid?and?beta?hydroxyl?butyric?acid?
?
?
44. The precursor of cholesterol synthesis is:
a. ?Acetic?acid?
b. ?Acetyl?CoA?
c. ?Oxalo?acetic?acid?
d. ?Pyruvate?
?
45. Which is not seen in HMG CoA pathway?
a. ?Pyruvate?
b. ?Cholesterol?
c. ?Mevalonate?
d. ?Acetyl?CoA?
?
46. Lipid from tissue is carried to liver by:
a. ?LDL?
b. ?VLDL?
c. ?HDL?
d. ?Chylomicrons?
?
47. Detoxification of drugs is controlled by:
a. ?Cytochrome?
b. ?Cytochrome?P450?
c. ?Cytochrome?C?
d. ?Cytochrome?A?
?
48. In Cytochrome p450, P stands for:
a. ?Structural?proteins?
b. ?Substrate?protiens?
c. ?Pigment?
d. ?Polyme?
?
49. Detoxification or protective synthesis occurs by:
a. ?Oxidation?
b. ?Reduction?
c. ?Conjugation?
d. ?Any?of?the?above?
?
50. Which of the following about biological membrane is true?
a. ?Lipid?moiety?is?amphipathic?
b. ?Rigid?assembly?of?protein,?lipid?and?carbohydrate?
c. ?Symmertrical?bi?leaflet?structures?
d. ?Lipid?and?protein?moiety?are?held?by?covalent?interactions?
?
51. The major driving force for formation of membrane lipid bilayer is:
a. ?Hydrogen?bonding?
b. ?Hydrophobic?interactions?
c. ?Vander?wall?forces?
d. ?Not?known?
?
52. Normal blood PH is:
a. ?6.8???7.0?
b. ?7.0???7.12?
c. ?7.38???7.4?
d. ?7.7???8.0?
?
53. The most important buffer in RBC is:
a. ?O
2
?Hb?+Na?hemoglobinate?
b. ?O
2
Hb?+K?hemoglobinate?
c. ?H
2
CO
3
?+?KHCO
3
?
d. ?H
2
CO
3
?+NAHCO
3
?
?
?
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Biochemistry??? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place?:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
1. Two Vitamin whose derivatives are involved in transformation of serine to glycine
are:
a. ?B
6
?ad?B
12
?
b. ?B
12
?and?nicotinamie?
c. ?Folic?acid?and?B
6
?
d. ?Folic?acid?and?B
12
?
2. Which vitamin is synthesized by intestinal bacteria?
a. ?Vit?B?
b. ?Vit?A?
c. ?Vit?D?
d. ?Vit?K?
3. Which vitamin is related to a co-factor in glycine metabolism is:
a. ?Vit?E?
b. ???Folic?acid?
c. ?Thiamine?
d. ?Cobalamine?
4. Biological activity of tocopherols has been attributed, in part to their actions as:
a. ?Antioxidant?
b. ?Anticoagulants?
c. ?Provitamin?
d. ?Antidotes?for?selenium?poisoning?
5. Vitamin C is present in largest amount in the body in:
a. ?Eye?
b. ?Kidneys?
c. ?Testes?
d. Adrenal?cortex?
?
6. The following vitamin is important in non-oxidative decarboxylation,
transamination and transsulfuration reactions:
a. ?Riboflavin?
b. ?Thiamine?
c. ?Pyridoxine?
d. ?Pantothenic?acid?
?
7. Most of vitamin B
12
in the body is stored as:
a. ?Methyl?B
12
?
b. ?Hydroxy?B
12
?
c. ?Cyano?cobalamine?
d. ?None?of?the?above?
?
8. Beri-beri is caused due to the deficiency of:
a. ?Thiamine?
b. Pyridoxine?
c. ?Ascorbic?acid?
d. ?Riboflavin?
?
9. Which of the following is not true of Vit D?
a. ?Its?active?form?is?calcitriol?
b. ?Increase?calcium?absorption?from?the?intestines?
c. ?Its?deficiency?results?in?rickets?
d. ?Its?decrease?cause?phosphate?reabsorption?from?the?kidneys?
?
10. The action of vitamin K in formation of clotting factor is through:
a. ?Post?transcription?
b. ?Post?translation?
c. ?Golgi?complex?
d. ?Endoplasmic?reticulum?
?
11. Specific disease caused by vitamin B
1
deficiency
a. ?Pellagra?
b. Angular?cheilitis?
c. ?Megaloblastic?anemia?
d. ?Peripheral?polyneuritis?
?
12. Deficiency of vitamin A causes the following except:
a. ?Night?blindness?
b. ?Corneal?dryness?
c. ?Bitot's?spots?
d. ?Myopia?
?
13. Active form of vitamin D in kidney is:?
a. ?1?dihydroxy?cholecalciferol?
b. ?25?hydroxy?cholecalciferol?
c. ?1,25?dihydroxy?cholecalciferol?
d. ?7?dihydroxy?calciferol?
?
14. Tertiary structure of protein is maintained by all except:
a. ?H
2
?bond?
b. ?Hydrophobic?
c. ?Ionic?bond?
d. ??None?of?the?above?
?
15. Which of the following is a derived a derived protein:
a. ?Protamines?
b. ?Peptones?
c. Prolamines?
d. ?Lactalbumin?
?
16. Quaternary structure of protein is:
a. ?The?arrangement?sequence?of?amino?acids?in?the?polypeptide?chain?
b. ?Inter?relation?between?amino?acids?in?a?single?polypeptide?chain?
c. ?Inter?relation?of?amino?acids?in?2?polypeptide?chains?
d. ?The? inter? relation? and? arrangement? of? polypeptides? in? a? protein?with? more?than? 2?
polypeptide?chains?
?
17. Indole ring is present in:
a. ?Tryptophan?
b. Valine?
c. ?Methionine?
d. ?Histidine?
?
18. The following is false about tryptophan:
a. ?Non?essential?amino?acid?
b. ?Involved?in?serotonin?synthesis?
c. Involved?in?niacin?synthesis?
d. Involved?in?melatonin?in?synthesis?
?
19. Non essential amino acids are not:
a. ?Used?by?the?body?
b. Forming?part?of?the?proteins?
c. ?Required?in?the?diet?
d. ?Absorbed?in?the?intestines?
?
20. The major fuel for the brain after several weeds of starvation:
a. ?Glucose?
b. ?Fatty?acid?
c. Beta?hydroxy?butyrate?
d. ?Glycerol?
?
21. One of the following is nonessential amino acid:
a. ?Tyrosine?
b. ?Valine?
c. ?Methionine?
d. ?Cystine?
?
22. The process by which a base sequence of messenger RNA is synthesized (by a RNA
polymerase) on a template of complementary DNA is called:
a. ?Transcription?
b. ?Transduction?
c. ?Translation?
d. ?Translocation?
?
23. Hydroxylation of proline require the following except:
a. ?Fe
+2
?
b. ?O
2
?
c. ?Ascorbic?acid?
d. ?Succinate?
?
24. The process of transfer of information from the RNA to the proteins is called:
a. ?Mutation?
b. ?Translation?
c. ?Transcription?
d. ?Conjugation?
?
25. The amino acid, which is used is the estimation of collagen is:
a. ?Hydroxyproline?
b. ?Proline?
c. ?Lysine?
d. ?Glycine?
?
26. Which of the following is present in the plasma but absent in the serum?
a. ?Albumin?
b. Globulin?
c. ?Lecithin?
d. Firbinogen?
?
27. Synthesis of protein occurs on:
a. ?Mitochondria?
b. Poly?ribosomes?
c. Nucleus?
d. Golgi?bodies?
?
28. Which of the following amino acids is quickly converted to tyrosine?
a. ?Arginine?
b. Glycinec?
c. Phenylalanine?
d. Leucine?
?
29. Alkaptonuria, an inherited metabolic disorder of L0tyrosine metabolism is due to
lack of:?
a. ?Parahydroxy?phenyl?pyruvate?Hydroxylase?
b. ?Tyrosine?transaminase?
c. ?Homogentisate?oxidase?
d. ?Tyrosine?oxidase?
?
30. During phagocytosis, the metabolic process called respiratory burst involves the
activation of:
a. ?Oxidase?
b. ?Hydrolase?
c. ?Peroxidase?
d. ?Dehydrogenase?
?
31. Heme is converted to bilirubin mainly in:
a. ?Kidney?
b. Liver?
c. ?Spleen?
d. ?Bone?marrow?
?
32. Fatty acid oxidation occurs in:
a. ?Cytoplasm?
b. ?Microsomes?
c. ?Mitochondria?
d. ?All?of?the?above?
?
33. Which of the following fatty acids are not syntehsised in human body:
a. ?Oleic,?linoleic?and?linolenic?acid?
b. ?Arachidonic,?linolenic?and?linoleic?acid?
c. ?Palmitic?Oleic?and?arachidonic?
d. ?Linoleic,?arachidonic?and?stearic?acid?
?
34. A fatty acid that is not synthesized in man is:
a. ?Linoleic?acid?
b. ?Oleic?acid?
c. ?Palmitic?acid?
d. ?Stearic?acid?
?
35. The lipoprotein particles that have the highest percentage concentration of
cholesterol is:
a. ?Chylomicron?
b. ?VLDL?(Very?low?density?lipoprotein)?
c. ?LDL?(Low?density?lipoprotein)?
d. ?HDL?(High?density?lipoprotein)?
?
?
?
?
36. Fat provides ____% of body?s calories
a. ?40%?
b. ?30%?
c. ?50%?
d. ?75%?
?
37. The major lipids that make up the cell membrane are:
a. ?Triglycerides?
b. ?Phospholipids?
c. ?Sphingomyelins?
d. ?Fatty?acids?
?
38. The following is not a phospholipid:
a. ?Sphingomyelin?
b. ?Lecithin?
c. ?Cerebroside?
d. ?Cephalin?
?
39. Which of the following is a phospholipid:
a. ?Glycogen?
b. ?Sphingomyelin?
c. ?Prostaglandin?
d. ?Oleic?acid?
?
40. In Niemann-Pick?s disease the following substrance accumulate in CNS in excess:
a. ?Glycerophosphatides?
b. ?Phosphoinositides?
c. ?Phosphosphingosides?
d. ?Glycerosphingosides?
?
41. The lipid, which acumulates in fatty liver, is:
a. ?Triglycerides?
b. ?FFA?
c. ?Lipoprotein?
d. ?Cholesterol?
?
42. The product of oxidation of odd chainfatty acids is:
a. ?Aceto?acetyl?CoA?
b. ?Malonyl?CoA?
c. ?Propionyl?CoA?
d. ?Fumaryl?CoA?
?
43. The ketone bodies, which are excreted in diabetic ketoacidosis?
a. ?Acetoacetic?acid?and?pyruvic?acid?
b. ?Acetoacetic?acid?and?oxalocacetic?acid?
c. ?Acetoacetic?acid?and?alpha?ketoglutaric?acid?
d. ?Acetoacetic?acid?and?beta?hydroxyl?butyric?acid?
?
?
44. The precursor of cholesterol synthesis is:
a. ?Acetic?acid?
b. ?Acetyl?CoA?
c. ?Oxalo?acetic?acid?
d. ?Pyruvate?
?
45. Which is not seen in HMG CoA pathway?
a. ?Pyruvate?
b. ?Cholesterol?
c. ?Mevalonate?
d. ?Acetyl?CoA?
?
46. Lipid from tissue is carried to liver by:
a. ?LDL?
b. ?VLDL?
c. ?HDL?
d. ?Chylomicrons?
?
47. Detoxification of drugs is controlled by:
a. ?Cytochrome?
b. ?Cytochrome?P450?
c. ?Cytochrome?C?
d. ?Cytochrome?A?
?
48. In Cytochrome p450, P stands for:
a. ?Structural?proteins?
b. ?Substrate?protiens?
c. ?Pigment?
d. ?Polyme?
?
49. Detoxification or protective synthesis occurs by:
a. ?Oxidation?
b. ?Reduction?
c. ?Conjugation?
d. ?Any?of?the?above?
?
50. Which of the following about biological membrane is true?
a. ?Lipid?moiety?is?amphipathic?
b. ?Rigid?assembly?of?protein,?lipid?and?carbohydrate?
c. ?Symmertrical?bi?leaflet?structures?
d. ?Lipid?and?protein?moiety?are?held?by?covalent?interactions?
?
51. The major driving force for formation of membrane lipid bilayer is:
a. ?Hydrogen?bonding?
b. ?Hydrophobic?interactions?
c. ?Vander?wall?forces?
d. ?Not?known?
?
52. Normal blood PH is:
a. ?6.8???7.0?
b. ?7.0???7.12?
c. ?7.38???7.4?
d. ?7.7???8.0?
?
53. The most important buffer in RBC is:
a. ?O
2
?Hb?+Na?hemoglobinate?
b. ?O
2
Hb?+K?hemoglobinate?
c. ?H
2
CO
3
?+?KHCO
3
?
d. ?H
2
CO
3
?+NAHCO
3
?
?
?
54. To keep blood PH at 7.4 the HCO
3
: H
2
CO
3
ratio should be:
a. ?20?:?1?
b. ?30?:?1?
c. ?15?:?1?
d. ?1?:?1?
?
55. In ECF main electrolyte is:
a. ?Na+?
b. ?K+?
c. ?Cl?
d. ?Proteins?
?
56. Most importent compansatory mechanism in metabolic acidosis:
a. ?Hyperventilation?
b. ?Increased?NH3?excretion?by?kidneys?
c. ?Increased?urinary?phosphates?
d. ?Increased?HCO3?Production?
?
57. The main function of mitochondria is:
a. ?Protein?synthesis?
b. ?Oxidation?
c. ?Electron?transfer?
d. ?Fat?synthesis?
?
58. Which cell organelle contains DNA
a. ?Mitochondrion?
b. ?Golgi?body?
c. ?Endoplasmic?reticulum?
d. ?Centriole?
?
59. Cell membrane consists of:
a. ?Lipids?and?proteins?
b. ?Lipids?only?
c. ?Protein?only?
d. ?None?of?the?above?
?
60. Golgi bodies function are:
a. ?Protein?lipid?synthesis?
b. ?Protein?synthesis?
c. ?Sorting?of?glycoproteins?
d. ?None?of?the?above?
?
?
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This post was last modified on 21 September 2020